{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,24]],"date-time":"2026-02-24T08:42:56Z","timestamp":1771922576762,"version":"3.50.1"},"reference-count":21,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T00:00:00Z","timestamp":1768867200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Cardiovasc. Med."],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      Aortic arch aneurysms involving branch vessels traditionally require open surgery with cardiopulmonary bypass, which poses prohibitive risks for octogenarians with complex comorbidities. This case demonstrates the successful application of total endovascular aortic repair (TEVAR) with three dimensional (3D) printing-assisted triple-vessel\n                      <jats:italic>in situ<\/jats:italic>\n                      fenestration and a diameter-restricting technique in an 85-year-old patient with a giant (9.0\u2005cm) aortic arch aneurysm involving the left subclavian artery.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation<\/jats:title>\n                    <jats:p>\n                      The involvement of the three arch branches (brachiocephalic trunk, left common carotid artery, and left subclavian artery) necessitated precise revascularization. In comparison with traditional\n                      <jats:italic>in situ<\/jats:italic>\n                      fenestration, 3D printing-guided\n                      <jats:italic>ex vivo<\/jats:italic>\n                      fenestration enabled pre-release stent modeling on a 1:1 aortic arch replica (error &amp;lt;1\u2005mm), allowing anatomically tailored fenestration positioning and eliminating blind puncture-related complications. A proximal stent diameter-restricting technique addressed the challenging anchoring zone gradient (33.6\u2009\u2192\u200927.3\u2005mm), improving stent apposition and reducing type I endoleak risk. Intraoperative multiaccess reconstruction (femoral\/axillary\/cervical approach) achieved complete aneurysm exclusion. Postoperative computed tomography angiography on day 4 confirmed patent branches and absence of endoleaks, while 6-month follow-up demonstrated stable stent position and no neurological complications.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      This case highlights that TEVAR with 3D printing-assisted\n                      <jats:italic>ex vivo<\/jats:italic>\n                      fenestration and a diameter-restricting technique can serve as a viable alternative to open surgery for high-risk octogenarians with complex aortic arch aneurysms, overcoming traditional limitations of\n                      <jats:italic>in situ<\/jats:italic>\n                      fenestration while preserving cerebral perfusion. Further studies are warranted to validate this approach in larger populations.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fcvm.2025.1650003","type":"journal-article","created":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T06:32:23Z","timestamp":1768890743000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["3D printing-assisted triple-vessel in situ fenestration combined with a diameter-restricting technique for a complex giant aortic arch aneurysm in an octogenarian: a case report and technical innovation"],"prefix":"10.3389","volume":"12","author":[{"given":"Xueshi","family":"Yin","sequence":"first","affiliation":[{"name":"The Department of Clinical Medicine, North Sichuan Medical College","place":["Nanchong, Sichuan, China"]},{"name":"Department of Cardiovascular Surgery, Suining Central Hospital","place":["Suining, Sichuan, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hanlin","family":"Chen","sequence":"additional","affiliation":[{"name":"The Department of Clinical Medicine, North Sichuan Medical College","place":["Nanchong, Sichuan, China"]},{"name":"Department of Cardiovascular Surgery, Suining Central Hospital","place":["Suining, Sichuan, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jing","family":"Ge","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Suining Central Hospital","place":["Suining, Sichuan, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Long","family":"Tang","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Suining Central Hospital","place":["Suining, Sichuan, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianping","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, 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