{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T06:36:59Z","timestamp":1762929419506,"version":"3.45.0"},"reference-count":20,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T00:00:00Z","timestamp":1762905600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004735","name":"Natural Science Foundation of Hunan Province","doi-asserted-by":"publisher","award":["2025JJ80988"],"award-info":[{"award-number":["2025JJ80988"]}],"id":[{"id":"10.13039\/501100004735","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Cardiovasc. Med."],"abstract":"<jats:p>We describe the management of a middle-aged male with hyperthyroidism who presented acute inferior myocardial infarction (AIMI) complicated by third-degree atrioventricular (AV) block. The symptoms of AIMI in the patient were atypical. However, his atypical presentation raised clinical suspicion. The electrocardiogram (ECG) was immediately conducted to confirm the patient's AIMI and third-degree AV block. Further coronary angiography revealed that the patient's right coronary artery was completely occluded at the second bend. A stent was placed in the right coronary artery. Following anti-thyroid therapy, the patient's clinical symptoms improved. This case underscores the importance of recognizing atypical presentations in hyperthyroid patients and is followed by a literature review exploring the mechanisms by which thyroid dysfunction influences coronary artery disease (CAD).<\/jats:p>","DOI":"10.3389\/fcvm.2025.1692856","type":"journal-article","created":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T06:32:52Z","timestamp":1762929172000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Case Report: Acute inferior myocardial infarction and third-degree atrioventricular block in a patient with hyperthyroidism"],"prefix":"10.3389","volume":"12","author":[{"given":"Qing","family":"Qiu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fen","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"RuYi","family":"Zhong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miao","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2025,11,12]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"3","DOI":"10.14797\/mdcj-6-2-3","article-title":"The cardiovascular effects of hyperthyroidism","volume":"6","author":"Nabbout","year":"2010","journal-title":"Methodist Debakey Cardiovasc J"},{"key":"B2","doi-asserted-by":"publisher","first-page":"379","DOI":"10.1111\/j.0954-6820.1960.tb17392.x","article-title":"Myocardial infarction in thyrotoxicosis","volume":"166","author":"Burstein","year":"1960","journal-title":"Acta Med Scand"},{"key":"B3","doi-asserted-by":"publisher","first-page":"2892","DOI":"10.1161\/CIRCULATIONAHA.118.036859","article-title":"Thyroid and cardiovascular disease: research agenda for enhancing knowledge, prevention, and treatment","volume":"139","author":"Cappola","year":"2019","journal-title":"Circulation"},{"key":"B4","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1210\/er.2006-0043","article-title":"The clinical significance of subclinical thyroid dysfunction","volume":"29","author":"Biondi","year":"2008","journal-title":"Endocr Rev"},{"key":"B5","doi-asserted-by":"publisher","first-page":"1756","DOI":"10.3390\/jcm13061756","article-title":"The influence of hyperthyroidism on the coagulation and on the risk of thrombosis","volume":"13","author":"Antonijevic","year":"2024","journal-title":"J Clin Med"},{"key":"B6","doi-asserted-by":"publisher","first-page":"700","DOI":"10.1136\/hrt.74.6.700","article-title":"Severe coronary vasospasm associated with hyperthyroidism causing myocardial infarction","volume":"74","author":"Masani","year":"1995","journal-title":"Br Heart J"},{"key":"B7","doi-asserted-by":"publisher","first-page":"137","DOI":"10.4103\/HEARTVIEWS.HEARTVIEWS_202_20","article-title":"Acute myocardial infarction attributed to coronary artery embolism in a patient with atrial fibrillation secondary to thyrotoxicosis - an underrecognized entity: a case report and literature review","volume":"22","author":"Abed","year":"2021","journal-title":"Heart Views"},{"key":"B8","first-page":"62","volume-title":"Practical Endocrinology","author":"Liu","year":"1997"},{"key":"B9","doi-asserted-by":"publisher","first-page":"664","DOI":"10.3969\/j.issn.1002-1949.2011.07.025","article-title":"Clinical analysis of patients with hyperthyroidism complicated with acute myocardial infarction","volume":"31","author":"Chen","year":"2011","journal-title":"Chin J Emerg Med"},{"key":"B10","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1093\/ehjcr\/ytaa191","article-title":"A case report of myocardial infarction with non-obstructive coronary artery disease: graves\u2019 disease-induced coronary artery vasospasm","volume":"4","author":"Klomp","year":"2020","journal-title":"Eur Heart J Case Rep"},{"key":"B11","doi-asserted-by":"publisher","first-page":"140","DOI":"10.14740\/jmc3473","article-title":"Coronary vasospasm-induced myocardial infarction: an uncommon presentation of unrecognized hyperthyroidism","volume":"11","author":"Ataallah","year":"2020","journal-title":"J Med Cases"},{"key":"B12","doi-asserted-by":"publisher","first-page":"e57","DOI":"10.1016\/j.ijcard.2011.06.034","article-title":"Repeated sudden cardiac death in coronary spasm: is IVUS helpful to decide treatment strategy?","volume":"154","author":"Park","year":"2012","journal-title":"Int J Cardiol"},{"key":"B13","doi-asserted-by":"publisher","first-page":"16-0063","DOI":"10.1530\/EDM-16-0063","article-title":"A rare case of gestational thyrotoxicosis as a cause of acute myocardial infarction","volume":"2016","author":"Nannaka","year":"2016","journal-title":"Endocrinol Diabetes Metab Case Rep"},{"key":"B14","doi-asserted-by":"publisher","first-page":"e26408","DOI":"10.7759\/cureus.26408","article-title":"Thyrotoxicosis-related left main coronary artery spasm presenting as acute coronary syndrome","volume":"14","author":"Anjum","year":"2022","journal-title":"Cureus"},{"key":"B15","doi-asserted-by":"publisher","first-page":"8127","DOI":"10.12998\/wjcc.v9.i27.8127","article-title":"Acute coronary syndrome with severe atherosclerotic and hyperthyroidism: a case report","volume":"9","author":"Zhu","year":"2021","journal-title":"World J Clin Cases"},{"key":"B16","doi-asserted-by":"publisher","first-page":"1333","DOI":"10.1089\/thy.2010.0180","article-title":"Relationships between thyroid function and lipid status or insulin resistance in a pediatric population","volume":"20","author":"Nader","year":"2010","journal-title":"Thyroid"},{"key":"B17","doi-asserted-by":"publisher","first-page":"384","DOI":"10.4183\/aeb.2024.384","article-title":"Iodinated contrast media induced thyroid storm and acute coronary syndrome: a case report","volume":"20","author":"Bjekic-Macut","year":"2024","journal-title":"Acta Endocrinol"},{"key":"B18","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1159\/000517175","article-title":"2021 European thyroid association guidelines for the management of iodine-based contrast Media-induced thyroid dysfunction","volume":"10","author":"Bednarczuk","year":"2021","journal-title":"Eur Thyroid J"},{"key":"B19","doi-asserted-by":"publisher","first-page":"473","DOI":"10.3760\/cma.j.cn112148-20241021-00631","article-title":"[Expert consensus on the diagnosis and management of cardiovascular disease complicated with thyroid dysfunction]","volume":"53","year":"2025","journal-title":"Zhonghua Xin Xue Guan Bing Za Zhi"},{"key":"B20","doi-asserted-by":"publisher","first-page":"221","DOI":"10.4103\/heartviews.heartviews_8_22","article-title":"Acute ST-elevation myocardial infarction in patient with severe uncontrolled hyperthyroidism complicated by thyroid storm","volume":"23","author":"Al Khodari","year":"2022","journal-title":"Heart Views"}],"container-title":["Frontiers in Cardiovascular Medicine"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fcvm.2025.1692856\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T06:32:56Z","timestamp":1762929176000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fcvm.2025.1692856\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,12]]},"references-count":20,"alternative-id":["10.3389\/fcvm.2025.1692856"],"URL":"https:\/\/doi.org\/10.3389\/fcvm.2025.1692856","relation":{},"ISSN":["2297-055X"],"issn-type":[{"value":"2297-055X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11,12]]},"article-number":"1692856"}}