{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T02:09:43Z","timestamp":1789610983021,"version":"build-2803163510"},"reference-count":79,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,11,20]],"date-time":"2025-11-20T00:00:00Z","timestamp":1763596800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Cardiovasc. Med."],"abstract":"<jats:p>To explore the potential benefits of Stellate ganglion block (SGB) in regulating the central and peripheral systems, as well as its potential as a treatment option for these diseases. We conducted a comprehensive search in PubMed, Web of Science, and Google Scholar libraries using the following keywords: stellate ganglion block, sympathetic nervous system, cardiovascular diseases, cerebrovascular diseases, and perioperative stress response. We selected and critically reviewed research articles published in English related to SGB modulation for the treatment of central and peripheral disease. The collected literature was classified according to content and reviewed in combination with experimental results and clinical cases. SGB can help regulate the cardiovascular and cerebrovascular systems by blocking sympathetic signals, reducing overactivation of the sympathetic nervous system linked to cardiovascular diseases. This local nerve block technique could be a treatment option for these conditions.<\/jats:p>","DOI":"10.3389\/fcvm.2025.1706435","type":"journal-article","created":{"date-parts":[[2025,11,20]],"date-time":"2025-11-20T13:19:31Z","timestamp":1763644771000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":6,"title":["The potential role of stellate ganglion block in impacting the central and peripheral systems: a narrative review"],"prefix":"10.3389","volume":"12","author":[{"given":"Zhongjie","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingzi","family":"An","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2025,11,20]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"300","DOI":"10.1161\/hypertensionaha.120.14521","article-title":"Neuronal 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