{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T09:21:27Z","timestamp":1772788887305,"version":"3.50.1"},"reference-count":7,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T00:00:00Z","timestamp":1772755200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Cardiovasc. Med."],"abstract":"<jats:p>Isolated right ventricular infarction (RVI) is an underrecognized clinical entity that often mimics anteroseptal myocardial infarction due to its characteristic ST-segment elevation (STE) in precordial leads. We report the case of a 55-year-old man who presented with acute chest pain and STE in leads V1 and V2. Despite typical anteroseptal infarction patterns, the electrocardiogram (ECG) revealed decremental STE (V1\u2009&amp;gt;\u2009V2), concomitant STE in lead III, and reciprocal ST depression in lateral leads. Coronary angiography confirmed proximal occlusion of the non-dominant right coronary artery. This case highlights the diagnostic challenges of isolated RVI and underscores key ECG features that distinguish it from anteroseptal infarction. Early recognition is imperative to avoid detrimental therapies (e.g., vasodilators) and to prioritize reperfusion and preload optimization.<\/jats:p>","DOI":"10.3389\/fcvm.2026.1731030","type":"journal-article","created":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T06:40:20Z","timestamp":1772779220000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Chest pain with elevated ST segment in lead V1: a case report"],"prefix":"10.3389","volume":"13","author":[{"given":"Zhongyong","family":"He","sequence":"first","affiliation":[{"name":"Department of Cardiology, Mianyang People\u2019s Hospital","place":["Mianyang, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaobo","family":"Pu","sequence":"additional","affiliation":[{"name":"Department of Cardiology, West China Hospital, Sichuan University","place":["Chengdu, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lijun","family":"Zeng","sequence":"additional","affiliation":[{"name":"Department of General Internal Medicine, West China Second University Hospital, Sichuan University","place":["Chengdu, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2026,3,6]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"473","DOI":"10.1002\/clc.4960230721","article-title":"Right ventricular infarction\u2013diagnosis and treatment","volume":"23","author":"Haji","year":"2000","journal-title":"Clin Cardiol"},{"key":"B2","doi-asserted-by":"publisher","first-page":"1211","DOI":"10.1056\/NEJM199404283301707","article-title":"Right ventricular infarction","volume":"330","author":"Kinch","year":"1994","journal-title":"N Engl J Med"},{"key":"B3","doi-asserted-by":"publisher","first-page":"740","DOI":"10.2459\/JCM.0b013e32835853a3","article-title":"Pathophysiology and ECG patterns of isolated right ventricular infarction with nondominant right coronary artery","volume":"14","author":"Iannetta","year":"2013","journal-title":"J Cardiovasc Med"},{"key":"B4","volume-title":"The ECG in Emergency Decision Making","author":"Wellens","year":"2006"},{"key":"B5","doi-asserted-by":"publisher","first-page":"140","DOI":"10.1016\/0002-9149(88)91380-x","article-title":"Value of the ST-T segment in lead V4R in inferior wall acute myocardial infarction to predict the site of coronary arterial occlusion","volume":"62","author":"Braat","year":"1988","journal-title":"Am J Cardiol"},{"key":"B6","doi-asserted-by":"publisher","first-page":"1327","DOI":"10.1161\/01.cir.72.6.1327","article-title":"Comparative effects of volume loading, dobutamine, and nitroprusside in patients with predominant right ventricular infarction","volume":"72","author":"Dell\u2019Italia","year":"1985","journal-title":"Circulation"},{"key":"B7","doi-asserted-by":"publisher","first-page":"1517","DOI":"10.1093\/europace\/eup234","article-title":"Distinguishing the right coronary artery from the left circumflex coronary artery as the infarct-related artery in patients undergoing primary percutaneous coronary intervention for acute inferior myocardial infarction","volume":"11","author":"Verouden","year":"2009","journal-title":"Europace"}],"container-title":["Frontiers in Cardiovascular Medicine"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fcvm.2026.1731030\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T06:40:22Z","timestamp":1772779222000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fcvm.2026.1731030\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,6]]},"references-count":7,"alternative-id":["10.3389\/fcvm.2026.1731030"],"URL":"https:\/\/doi.org\/10.3389\/fcvm.2026.1731030","relation":{},"ISSN":["2297-055X"],"issn-type":[{"value":"2297-055X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,6]]},"article-number":"1731030"}}