{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T08:54:54Z","timestamp":1773392094574,"version":"3.50.1"},"reference-count":31,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T00:00:00Z","timestamp":1773360000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Cardiovasc. Med."],"abstract":"<jats:p>\n                    Marfan syndrome (MFS) is a congenital connective tissue disorder whose cardiovascular manifestations primarily affect the ascending aorta, presenting as ascending aortic aneurysm, aortic annulus dilation, aortic valve insufficiency, and aortic dissection (\n                    <jats:xref>1<\/jats:xref>\n                    ). It has a poor prognosis and a high mortality rate.This article reports a case of a patient with MFS and acute Stanford type A aortic dissection. Hematoma compression led to left main coronary artery occlusion, resulting in a large myocardial infarction and severe low cardiac output syndrome. The patient was ultimately treated with a modified axillary artery cannulation for ECMO bridging therapy. This case study focuses on the advantages of ECMO cannulation using an axillary artery bridging graft over traditional peripheral and central cannulation, this cannulation technique offers advantages such as optimized hemodynamics, significantly reduced risk of limb ischemia, fewer infectious complications, and improved cerebral and coronary perfusion, making it one of the more ideal ECMO cannulation strategies. Despite initial success with ECMO support, the patient ultimately abandoned a left ventricular assist device (LVAD) and heart transplantation for financial reasons, resulting in clinical death. This case explores a modified axillary artery cannulation method to achieve antegrade blood flow, avoiding the complications of severe left ventricular afterload and left ventricular dilatation.\n                  <\/jats:p>","DOI":"10.3389\/fcvm.2026.1735797","type":"journal-article","created":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T06:47:53Z","timestamp":1773384473000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Case Report: Improved axillary artery cannulation and extracorporeal membrane oxygenation bridging therapy for cardiogenic shock caused by Marfan syndrome combined with aortic dissection"],"prefix":"10.3389","volume":"13","author":[{"given":"Fangfang","family":"Qiu","sequence":"first","affiliation":[{"name":"Department of Critical Care Medicine, the Fourth Affiliated Hospital of School of Medicine, and International School of Medicine, International Institutes of Medicine, Zhejiang University","place":["Yiwu, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lihan","family":"Luo","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine, the Fourth Affiliated Hospital of School of Medicine, and International School of Medicine, International Institutes of Medicine, Zhejiang University","place":["Yiwu, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junchao","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Cardio-Thoracic Surgery, The Fourth Affiliated Hospital of School of Medicine, and International School of Medicine, International Institutes of Medicine, Zhejiang University","place":["Yiwu, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jinshan","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Cardio-Thoracic Surgery, The Fourth Affiliated Hospital of School of Medicine, and International School of Medicine, International Institutes of Medicine, Zhejiang University","place":["Yiwu, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2026,3,13]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"476","DOI":"10.1136\/jmg.2009.072785","article-title":"The revised Ghent nosology for the Marfan syndrome","volume":"47","author":"Loeys","year":"2010","journal-title":"J Med Genet"},{"key":"B2","doi-asserted-by":"publisher","first-page":"1509","DOI":"10.1016\/j.jacc.2010.02.010","article-title":"2010 ACCF\/AHA\/AATS\/ACR\/ASA\/SCA\/SCAI\/SIR\/STS\/SVM guidelines for the diagnosis and management of patients with thoracic aortic disease","volume":"55","author":"Hiratzka","year":"2010","journal-title":"J Am Coll Cardiol"},{"key":"B3","doi-asserted-by":"publisher","first-page":"1","DOI":"10.12968\/hmed.2023.0366","article-title":"Diagnosis and management of acute aortic dissection in the emergency 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