{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T06:11:20Z","timestamp":1783923080500,"version":"3.55.0"},"reference-count":22,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T00:00:00Z","timestamp":1783900800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100011176","name":"Peking Union Medical College","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100011176","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Cardiovasc. Med."],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Vasodepressor syncope is a common subtype of reflex syncope. Although lifestyle modification, trigger avoidance, physical counterpressure manoeuvres, and orthostatic training are recommended, post-discharge nursing pathways that translate this evidence into individualized home-based care remain insufficiently described.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation<\/jats:title>\n                    <jats:p>We report two patients with tilt-test-confirmed vasodepressor syncope. Patient A was a 58-year-old man with recurrent brief syncopal episodes, fall-related injury, and insufficient prodrome recognition and self-monitoring. Patient B was a 74-year-old woman with recurrent dizziness and syncope-like episodes, blood pressure variability, cerebrovascular comorbidity, and higher anxiety related to unpredictable episodes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Intervention<\/jats:title>\n                    <jats:p>An evidence-based personalized nursing care pathway was developed using guideline recommendations, syncope-related clinical studies, and individualized patient assessment. The intervention included lifestyle modification, fluid and salt intake guidance, physical counterpressure manoeuvre training, orthostatic\/tilt training, blood pressure and heart-rate self-monitoring, trigger management, family involvement, and psychological support. Follow-up was performed by telephone and outpatient review over 3 weeks.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Outcomes<\/jats:title>\n                    <jats:p>No syncope recurrence, fall event, or other major discomfort occurred during the 3-week follow-up. Patient A showed improvement in EQ-5D-5L index from 0.720 to 0.906 and EQ VAS from 58 to 75; GAD-7 decreased from 8 to 5 and FES-I from 48 to 32. Patient B showed improvement in EQ-5D-5L index from 0.467 to 0.651 and EQ VAS from 48 to 66; GAD-7 decreased from 15 to 10 and FES-I from 44 to 36.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>A structured personalized nursing care pathway may support self-management, fall-prevention behaviours, and patient-reported outcomes in vasodepressor syncope. As this report involves only two cases and a short follow-up, the absence of recurrence should be interpreted as an early observation requiring prospective verification.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fcvm.2026.1780380","type":"journal-article","created":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T05:35:32Z","timestamp":1783920932000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Implementation of evidence-based personalized nursing care for Two patients With vasodepressor syncope: a case report"],"prefix":"10.3389","volume":"13","author":[{"given":"Yunfeng","family":"Bai","sequence":"first","affiliation":[{"name":"Department of Nursing, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tianchao","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Nursing, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Fu","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nan","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinjuan","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Nursing, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,7,13]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1016\/j.ejim.2023.03.025","article-title":"Vasovagal syncope: an overview of pathophysiological mechanisms","volume":"112","author":"Longo","year":"2023","journal-title":"Eur J Intern Med"},{"key":"B2","doi-asserted-by":"publisher","first-page":"1883","DOI":"10.1093\/eurheartj\/ehy037","article-title":"ESC Scientific document group. 2018 ESC guidelines for the diagnosis and management of syncope","volume":"39","author":"Brignole","year":"2018","journal-title":"Eur Heart J"},{"key":"B3","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1007\/s10286-011-0119-5","article-title":"Consensus statement on the definition of orthostatic hypotension, neurally mediated syncope and postural tachycardia syndrome","volume":"21","author":"Freeman","year":"2011","journal-title":"Clin Auton Res"},{"key":"B4","doi-asserted-by":"publisher","first-page":"727","DOI":"10.3390\/jcm13030727","article-title":"Recent advances and future directions in syncope management: a comprehensive narrative review","volume":"13","author":"Martone","year":"2024","journal-title":"J Clin Med"},{"key":"B5","doi-asserted-by":"publisher","first-page":"590","DOI":"10.1111\/jce.16546","article-title":"Syncope: advances in diagnosis and treatment 2024","volume":"36","author":"Sutton","year":"2025","journal-title":"J Cardiovasc Electrophysiol"},{"key":"B6","doi-asserted-by":"publisher","first-page":"e60","DOI":"10.1161\/CIR.0000000000000499","article-title":"2017 ACC\/AHA\/HRS guideline for the evaluation and management of patients with syncope","volume":"136","author":"Shen","year":"2017","journal-title":"Circulation"},{"key":"B7","doi-asserted-by":"publisher","first-page":"123","DOI":"10.15420\/ecr.2015.10.2.1","article-title":"Home orthostatic training in elderly patients with vasovagal syncope: a prospective randomised controlled trial","volume":"10","author":"Podd","year":"2015","journal-title":"Eur Cardiol"},{"key":"B8","doi-asserted-by":"publisher","first-page":"1652","DOI":"10.1016\/j.jacc.2006.06.059","article-title":"PC-Trial Investigators. 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