{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T07:05:18Z","timestamp":1784099118816,"version":"3.55.0"},"reference-count":21,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T00:00:00Z","timestamp":1784073600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Cardiovasc. Med."],"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This randomized controlled trial evaluated the effects of an early, graduated mobilization program on functional recovery (primary endpoint: postoperative day-5 forced vital capacity [FVC]; secondary endpoints: activities of daily living [ADL] scores, handgrip strength, Short Physical Performance Battery [SPPB] scores, postoperative pulmonary complications [PPCs], and postoperative length of stay) in patients undergoing on-pump coronary artery bypass grafting (CABG).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Between March to September 2025, 92 patients underwent on-pump CABG; after screening, 80 consecutive eligible patients (sample size calculated based on PPC incidence,\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200942 per group before attrition adjustment) were randomized 1:1 using a random number table with allocation concealment to a control group (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200940) or an intervention group (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200940).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      On postoperative day 5, the intervention group demonstrated significantly better FVC, ADL scores, handgrip strength, and SPPB scores (all\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&amp;lt;\u20090.05). PPC incidence was markedly lower (10% vs. 62.5%,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&amp;lt;\u20090.0001), and postoperative length of stay was shorter (7.13\u2009\u00b1\u20092.36 vs. 9.18\u2009\u00b1\u20092.66 days,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.0006).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The early graduated mobilization program was safe, feasible, and associated with improved short-term functional recovery, reduced PPCs, and shorter postoperative hospital stay after on-pump CABG. Larger multicenter studies with longer follow-up are required to confirm long-term safety and effectiveness.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fcvm.2026.1801971","type":"journal-article","created":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T06:10:59Z","timestamp":1784095859000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Impact of an early, graduated mobilization program on recovery and postoperative outcomes after cardiac revascularization with extracorporeal circulation"],"prefix":"10.3389","volume":"13","author":[{"given":"Jiaqi","family":"Liu","sequence":"first","affiliation":[{"name":"Cardiac Surgery Department, The First Hospital of Jilin University","place":["Changchun, Jilin Province, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mi","family":"Jiang","sequence":"additional","affiliation":[{"name":"Cardiac Surgery Department, The First Hospital of Jilin University","place":["Changchun, Jilin Province, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuewen","family":"Zhao","sequence":"additional","affiliation":[{"name":"Cardiac Surgery Department, The First Hospital of Jilin University","place":["Changchun, Jilin Province, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yingdan","family":"Liang","sequence":"additional","affiliation":[{"name":"Cardiac Surgery Department, The First Hospital of Jilin University","place":["Changchun, Jilin Province, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Liu","sequence":"additional","affiliation":[{"name":"Cardiac Surgery Department, The First Hospital of Jilin University","place":["Changchun, Jilin Province, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruijin","family":"Pan","sequence":"additional","affiliation":[{"name":"Cardiac Surgery Department, The First Hospital of 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