{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T05:18:21Z","timestamp":1787894301308,"version":"build-2784847793"},"reference-count":28,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T00:00:00Z","timestamp":1787875200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Cardiovasc. Med."],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Post-market long-term surveillance data for aortic endovascular devices are essential due to evolving regulatory standards and clinical practice demands. Building upon the successful Global Registry for Endovascular Aortic Treatment (GREAT), comprehensive real-world data is required to address current gaps in long-term device performance and patient outcomes. Thus, the purpose of this manuscript is to describe the protocol, objectives, and anticipated outcomes of the Gore Together Aortic Registry, designed for extensive real-world evaluation of the performance and clinical outcomes of aortic endovascular devices.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The Gore Together Aortic Registry is an international, prospective, observational registry initiated in response to increased regulatory emphasis on long-term post-market surveillance. This registry will enroll approximately 3,355 adult patients (\u226518 years old) from over 170 global clinical centers, undergoing routine clinical care with GORE\u00ae aortic endovascular devices. Enrollment commenced based on standard clinical application, with data and imaging collection beginning at the time of hospitalization, and at each follow-up period.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Ethics and dissemination<\/jats:title>\n                    <jats:p>Primary registry outcomes include technical deployment success, measures of device or procedural adverse events, including endoleaks, as well as post-procedure reinterventions. Individual modules can tailor their reporting to address pertinent needs that may include dissection characterization, neurological complications or renal dysfunction. Follow-up is collected per standard of care with the potential to capture up to 10 years of data based upon device need. Patient enrollment is ongoing; no results are reported at this stage.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The Gore Together Aortic Registry aims to deliver robust and granular real-world data regarding mid-term clinical outcomes of aortic endovascular devices, enhancing patient care strategies and meeting evolving global regulatory expectations. Results will guide clinical decisions, inform regulatory oversight, and potentially improve device safety and efficacy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical trial registration<\/jats:title>\n                    <jats:p>\n                      The individual modules of the Gore Together Aortic Registry are registered in\n                      <jats:ext-link>ClinicalTrials.gov<\/jats:ext-link>\n                      as:\n                      <jats:list>\n                        <jats:list-item>\n                          <jats:p>\n                            <jats:ext-link>https:\/\/clinicaltrials.gov\/study\/NCT06218875<\/jats:ext-link>\n                            , identifier NCT06218875\n                          <\/jats:p>\n                        <\/jats:list-item>\n                        <jats:list-item>\n                          <jats:p>\n                            <jats:ext-link>https:\/\/clinicaltrials.gov\/study\/NCT06507865<\/jats:ext-link>\n                            , identifier NCT06507865\n                          <\/jats:p>\n                        <\/jats:list-item>\n                        <jats:list-item>\n                          <jats:p>\n                            <jats:ext-link>https:\/\/clinicaltrials.gov\/study\/NCT06658730<\/jats:ext-link>\n                            , identifier NCT06658730\n                          <\/jats:p>\n                        <\/jats:list-item>\n                      <\/jats:list>\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fcvm.2026.1803528","type":"journal-article","created":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T04:32:01Z","timestamp":1787891521000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Real-world data on aortic endografts: Gore Together aortic registry protocol"],"prefix":"10.3389","volume":"13","author":[{"given":"Dai","family":"Yamanouchi","sequence":"first","affiliation":[{"name":"Division of Vascular Surgery, University of Wisconsin School of Medicine and Public Health","place":["Madison, WI, United States"]},{"name":"Department of Vascular Surgery, Fujita Health University","place":["Toyoake, Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manar","family":"Khashram","sequence":"additional","affiliation":[{"name":"Department of Vascular and Endovascular Surgery, Waikato Hospital, University of Auckland Hamilton","place":["Hamilton, New Zealand"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dennis","family":"Gable","sequence":"additional","affiliation":[{"name":"Department of Vascular and Endovascular Surgery, Baylor Scott and White Heart Hospital Plano","place":["Plano, TX, United 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Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dittmar","family":"B\u00f6ckler","sequence":"additional","affiliation":[{"name":"Department of Vascular and Endovascular Surgery, University Hospital Heidelberg","place":["Heidelberg, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chris","family":"Delaney","sequence":"additional","affiliation":[{"name":"Department of Vascular and Endovascular Surgery, Flinders Medical Centre","place":["Adelaide, SA, Australia"]},{"name":"College of Medicine and Public Health, Flinders University","place":["Adelaide, SA, Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali","family":"Azizzadeh","sequence":"additional","affiliation":[{"name":"Division of Vascular Surgery, Smidt Heart Institute and Randall Department of Surgery, Cedars-Sinai Medical Center","place":["Los Angeles, CA, United 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