{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T14:10:42Z","timestamp":1778163042434,"version":"3.51.4"},"reference-count":24,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T00:00:00Z","timestamp":1777420800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Cardiovasc. Med."],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The impact of off-pump coronary artery bypass grafting (OPCAB) on great saphenous vein (GSV) harvest-site wound complications and graft integrity remains uncertain in the contemporary era. We compared harvest-site morbidity, early angiographic outcomes, and long-term clinical events between OPCAB and conventional on-pump coronary artery bypass grafting (CABG).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      This single-center retrospective study included 394 patients who underwent isolated CABG with available pre- and postoperative coronary angiography between 2005 and 2017. Propensity score matching according to pump usage yielded 157 matched pairs [on-pump CABG,\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009157; OPCAB,\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009157]. The primary endpoint was GSV harvest-site wound complications. Secondary endpoints included early graft occlusion or saphenous vein graft (SVG) stenosis, reintervention, perioperative outcomes, and major adverse cardiac and cerebrovascular events (MACCE).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      After matching, baseline characteristics were comparable, although the on-pump group had more distal anastomoses. Leg wound complications were rare and similar between groups (1.3% vs. 0.6%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20091.00). Early graft occlusion (9.6% vs. 10.3%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.553) and SVG occlusion (5.7% vs. 4.5%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.798) did not differ significantly. SVG stenosis severity and reintervention rates were comparable. OPCAB was associated with shorter operative time, fewer red blood cell transfusions (49.7% vs. 64.3%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.012), shorter intensive care unit stay, and reduced hospital stay. Thirty-day mortality and 12-month MACCE rates (12.1% in both groups) were similar. Long-term MACCE-free survival up to 10 years showed no significant difference.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>OPCAB did not reduce GSV harvest-site complications compared with on-pump CABG. Early graft integrity and long-term clinical outcomes were comparable, although OPCAB improved perioperative resource utilization.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fcvm.2026.1823140","type":"journal-article","created":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T04:31:09Z","timestamp":1777437069000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["OPCAB in the minimally invasive era: impact on wound complications\u2014a comparative study with on-pump CABG"],"prefix":"10.3389","volume":"13","author":[{"given":"Ken","family":"Nakamura","sequence":"first","affiliation":[{"name":"Division of Cardiovascular Surgery, Nihonkai General Hospital","place":["Sakata, Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kentaro","family":"Akabane","sequence":"additional","affiliation":[{"name":"Second Department of Surgery, Yamagata University Faculty of 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