{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T07:02:28Z","timestamp":1780038148331,"version":"3.53.1"},"reference-count":19,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T00:00:00Z","timestamp":1780012800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Cardiovasc. Med."],"abstract":"<jats:p>\n                    A 75-year-old woman accidentally ingested approximately 10\u2005g of the rhizome of\n                    <jats:italic>Alocasia macrorrhizos<\/jats:italic>\n                    . Within seconds, she developed oral numbness, throat swelling, sialorrhea, dysphagia, and heartburn. She immediately rinsed her mouth with copious amounts of water and presented to a local clinic. An electrocardiogram (ECG) obtained there was normal, with a corrected QT interval (QTc) of 400\u2005ms. Following treatment with anti-allergic therapy, her symptoms resolved. Approximately 26\u2005h after ingestion, she developed persistent, progressive substernal chest pressure. Upon presentation to our hospital (28\u2005h post-ingestion), her cardiac troponin I (cTnI) level was 0.352\u2005ng\/mL, while myocardial enzymes and D-dimer were within normal limits. The ECG revealed diffuse T-wave inversions and a markedly prolonged QTc interval of 590\u2005ms. Coronary angiography showed no obstructive lesions and normal coronary flow. Echocardiography demonstrated reduced wall motion in the mid-segment of the left ventricular anterior wall, consistent with a MINOCA-like phenotype. A final diagnosis of toxic myocardial injury was made. Following supportive care, including continuous ECG monitoring, myocardial metabolic support, and rate control with low-dose metoprolol, her chest pain completely resolved approximately 124\u2005h after ingestion. The QTc interval normalized to 440\u2005ms, T-wave inversions became less pronounced, and regional wall motion abnormalities resolved. At a 2-week follow-up, the QTc interval was 420\u2005ms, with further improvement in T-wave inversions.\n                  <\/jats:p>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      This case demonstrates that\n                      <jats:italic>Alocasia<\/jats:italic>\n                      poisoning can cause marked QTc prolongation, diffuse T-wave inversions, and reversible segmental wall motion abnormalities, presenting with a MINOCA-like phenotype. Notably, the patient exhibited significant QTc prolongation despite only mildly elevated cardiac biomarkers, suggesting that the predominant mechanism of toxic myocardial injury in this context may be electrophysiological derangement rather than structural myocyte necrosis. In patients presenting with chest pain accompanied by pronounced QTc prolongation, only mildly elevated cardiac biomarkers, and normal coronary angiography, a detailed exposure history, including inquiry about plants, should be routinely obtained, and continuous ECG monitoring is warranted.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fcvm.2026.1833677","type":"journal-article","created":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T06:11:04Z","timestamp":1780035064000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Case Report: Alocasia poisoning presenting with marked QTc prolongation and a MINOCA-like phenotype"],"prefix":"10.3389","volume":"13","author":[{"given":"Jin-Mei","family":"Xie","sequence":"first","affiliation":[{"name":"Department of Electrocardiogram Diagnosis, Sanming First Hospital Affiliated to Fujian Medical University","place":["Sanming, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ren-Rong","family":"Lu","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Sanming First Hospital Affiliated to Fujian Medical University","place":["Sanming, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zong-Jie","family":"Zheng","sequence":"additional","affiliation":[{"name":"Department of Ultrasound Medicine, Sanming First Hospital Affiliated to Fujian Medical University","place":["Sanming, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Sanming First Hospital Affiliated to Fujian Medical University","place":["Sanming, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheng-Hua","family":"Shan","sequence":"additional","affiliation":[{"name":"Department of Electrocardiogram Diagnosis, Sanming First 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