{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T13:56:15Z","timestamp":1781272575204,"version":"3.54.1"},"reference-count":24,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T00:00:00Z","timestamp":1781222400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Cardiovasc. Med."],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Magmaris is a bioresorbable magnesium scaffold that has shown favorable safety and efficacy in the treatment of de-novo coronary lesions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>To report 1-year outcomes after Magmaris implantation in patients with predominantly complex coronary lesions in the Resorbable Magnesium Scaffold registry (RMS) and to compare them with outcomes from patients with mainly non-complex lesions in the BIOSOLVE-IV registry.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The RMS registry is an ongoing, prospective, national, multicenter registry conducted in Germany. Enrollment took place from November 2020 until May 2023 at Cardiovascular Center Oberallgaeu-Kempten, Bavaria, Germany. Follow-up was performed by phone 12 months after index procedure. We report 1-year outcomes of the first 100 consecutively enrolled patients and provide an unadjusted statistical comparison with 1-year outcomes from the BIOSOLVE-IV registry.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      RMS patients were older (64.9\u2009\u00b1\u20098.5 vs. 61.9\u2009\u00b1\u200910.5 years;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.006) and had a significantly more complex lesion profile (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&amp;lt;\u20090.001), with higher rates of type B2\/C lesions (74.0% vs. 15.1%) and moderate-to-severe calcification (24.0% vs. 7.5%), whereas lesion length was similar between the registries (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.118). At 12 months, target-lesion failure did not differ significantly between RMS and BIOSOLVE-IV (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.885), while scaffold thrombosis was numerically more frequent in RMS (2.0% vs. 0.8%;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.384).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Despite a more complex lesion profile in RMS, no statistically significant differences in 1-year clinical outcomes were observed between the two registries. This analysis is hypothesis-generating though not conclusive. Conclusive analysis can only be provided by a randomized controlled trial.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical Trial Registration<\/jats:title>\n                    <jats:p>RMS registry, NCT04679740.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fcvm.2026.1854686","type":"journal-article","created":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T12:59:48Z","timestamp":1781269188000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["One-year outcomes of bioresorbable magnesium scaffold implantation in complex coronary lesions"],"prefix":"10.3389","volume":"13","author":[{"given":"Simon","family":"W\u00f6lbert","sequence":"first","affiliation":[{"name":"Department of Cardiology, Cardiovascular Center Oberallg\u00e4u-Kempten","place":["Kempten, Germany"]},{"name":"Department of Internal Medicine I, University Hospital Augsburg","place":["Augsburg, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Schmidt","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Cardiovascular Center Oberallg\u00e4u-Kempten","place":["Kempten, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabian","family":"Wittek","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Cardiovascular Center Oberallg\u00e4u-Kempten","place":["Kempten, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin","family":"Mayer","sequence":"additional","affiliation":[{"name":"Institute of Epidemiology and Medical Biometry, University of Ulm","place":["Ulm, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip","family":"Raake","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine I, University Hospital Augsburg","place":["Augsburg, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dario","family":"Bongiovanni","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine I, University Hospital Augsburg","place":["Augsburg, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"Torzewski","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Cardiovascular Center Oberallg\u00e4u-Kempten","place":["Kempten, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,6,12]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"e531","DOI":"10.1161\/CIR.0000000000001303","article-title":"2025 Heart disease and stroke statistics: a report of US and global data from the American Heart 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