{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T06:18:08Z","timestamp":1783577888691,"version":"3.55.0"},"reference-count":36,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T00:00:00Z","timestamp":1783555200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Cardiovasc. Med."],"abstract":"<jats:sec>\n                    <jats:title>Background and aims<\/jats:title>\n                    <jats:p>In the face of escalating cardiovascular disease (CVD) prevalence, the demand for evidence-backed cardiac rehabilitation has surged, making it a guideline-recommended secondary prevention and adjunctive management strategy for afflicted individuals.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Our study meticulously investigated the effects of a structured cardiac rehabilitation (CR) program on 79 CVD patients. These participants engaged in a carefully designed regimen, including 12 in-center sessions held 2\u20133 times per week, with comprehensive assessments conducted both before and after the intervention. These assessments encompassed a cardiopulmonary exercise test (CPET) and the completion of four questionnaires targeting aspects of quality of life and mental health, specifically depression and anxiety levels.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Following the cardiac rehabilitation, oxygen uptake (VO\n                      <jats:sub>2<\/jats:sub>\n                      , 10.9\u2009\u00b1\u20092.9 to 13.3\u2009\u00b1\u20093.4\u2005mL\/min\/kg,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&amp;lt;\u20090.01), ventilation (VE, 29.3\u2009\u00b1\u20097.5 to 35.6\u2009\u00b1\u20099.3\u2005mL\/min\/kg,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&amp;lt;\u20090.01), workload (56.7\u2009\u00b1\u200925.4 to 70.0\u2009\u00b1\u200927.7 W,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&amp;lt;\u20090.01) at the anaerobic threshold (AT), and the oxygen uptake efficiency slope (OUES, 1,426.8\u2009\u00b1\u2009346.3 to 1,547.2\u2009\u00b1\u2009403.5,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&amp;lt;\u20090.01) significantly improved in CVD patients. These positive outcomes were consistent across study groups. Additionally, participants experienced significant enhancements in quality of life, coupled with reduced depression and anxiety levels post-rehabilitation.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Collectively, the present study corroborates compelling evidence that exercise-driven cardiac rehabilitation confers meaningful improvements in physical performance and quality of life for patient cohorts irrespective of body mass index.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fcvm.2026.1875972","type":"journal-article","created":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T05:36:09Z","timestamp":1783575369000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Enhanced physical performance and quality of life in cardiovascular disease patients across BMI groups through exercise-based cardiac rehabilitation"],"prefix":"10.3389","volume":"13","author":[{"given":"Xinmeng","family":"Liu","sequence":"first","affiliation":[{"name":"Department of Rehabilitation Medicine, Tianjin Chest Hospital","place":["Tianjin, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guangxin","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine, Tianjin Chest Hospital","place":["Tianjin, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zibo","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Medical Equipment, Tianjin Chest Hospital","place":["Tianjin, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingxiang","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine, Tianjin Chest Hospital","place":["Tianjin, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deyu","family":"Qin","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine, Tianjin Chest Hospital","place":["Tianjin, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chaodong","family":"Pu","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine, Tianjin Chest Hospital","place":["Tianjin, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qian","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine, Tianjin Chest Hospital","place":["Tianjin, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine, Tianjin Chest Hospital","place":["Tianjin, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mei","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine, Tianjin Chest Hospital","place":["Tianjin, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,7,9]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"342","DOI":"10.1001\/jamacardio.2019.0295","article-title":"Burden of cardiovascular diseases in China, 1990\u20132016: findings from the 2016 global burden of disease study","volume":"4","author":"Liu","year":"2019","journal-title":"JAMA Cardiol"},{"key":"B2","doi-asserted-by":"publisher","first-page":"2982","DOI":"10.1016\/j.jacc.2020.11.010","article-title":"Global burden of cardiovascular diseases and risk factors, 1990\u20132019: update from the GBD 2019 study","volume":"76","author":"Roth","year":"2020","journal-title":"J Am Coll 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