{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T06:06:32Z","timestamp":1784700392050,"version":"3.55.0"},"reference-count":12,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T00:00:00Z","timestamp":1784678400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Cardiovasc. Med."],"abstract":"\n Background<\/jats:title>\n Left ventricular pseudoaneurysm (LVPA) is a rare and potentially fatal complication of myocardial infarction (MI), with mortality reaching 48% in untreated patients. While surgical repair has been the conventional therapy, perioperative mortality of 10%\u201336% renders it prohibitive in patients with multiple comorbidities. Percutaneous transcatheter closure has emerged as a life-saving alternative for high-risk surgical candidates.<\/jats:p>\n <\/jats:sec>\n \n Case report<\/jats:title>\n A 75-year-old male with prior coronary artery bypass grafting (2010) and two subsequent myocardial infarctions (2019 and 2020) treated with percutaneous coronary intervention presented with refractory decompensated heart failure, massive left pleural effusion, and markedly elevated NT-proBNP (7,172\u2005pg\/mL). Cardiac magnetic resonance imaging revealed a giant LVPA (61\u2005mm\u2009\u00d7\u200928\u2005mm; end-diastolic volume 55\u2005mL) arising from the lateral-to-posterolateral wall, with transmural late gadolinium enhancement confirming a post-infarction etiology. After multidisciplinary heart-team consensus, percutaneous transcatheter closure was performed via a transfemoral retrograde approach under transesophageal echocardiographic guidance using a 16\u2005mm Amplatzer Muscular VSD Occluder. The procedure was uncomplicated, with no significant residual flow. The patient was discharged on postoperative day 2. At 3-month follow-up, he was in NYHA class I-II with marked symptomatic improvement, NT-proBNP reduction to \u223c500\u2005pg\/mL, and no residual flow.<\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n Percutaneous transcatheter closure with an Amplatzer Muscular VSD Occluder is a feasible, safe, and life-saving therapeutic option in selected high-risk patients with post-infarction LVPA presenting with refractory heart failure.<\/jats:p>\n <\/jats:sec>","DOI":"10.3389\/fcvm.2026.1879721","type":"journal-article","created":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T05:52:57Z","timestamp":1784699577000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Percutaneous closure of a giant left ventricular pseudoaneurysm using an Amplatzer muscular VSD occluder in a high-risk patient with recurrent heart failure following multiple myocardial infarctions"],"prefix":"10.3389","volume":"13","author":[{"given":"Senol","family":"Coskun","sequence":"first","affiliation":[{"name":"Faculty of Health Sciences, Kocaeli Health and Technology University","place":["Kocaeli, T\u00fcrkiye"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saim","family":"Sag","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Ac\u0131badem Bursa Hospital","place":["Bursa, T\u00fcrkiye"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Osman","family":"Ozdabakoglu","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Ac\u0131badem Bursa Hospital","place":["Bursa, T\u00fcrkiye"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teoman","family":"Kilic","sequence":"additional","affiliation":[{"name":"Structural Heart Interventions Unit, Department of Cardiology, Kocaeli University School of Medicine","place":["Kocaeli, T\u00fcrkiye"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,7,22]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"557","DOI":"10.1016\/S0735-1097(98)00290-3","article-title":"Left ventricular pseudoaneurysm","volume":"32","author":"Frances","year":"1998","journal-title":"J Am Coll Cardiol"},{"key":"B2","first-page":"47","article-title":"Surgical treatment of post-infarction left ventricular pseudoaneurysm: a two-decade experience","volume":"34","author":"Eren","year":"2007","journal-title":"Tex Heart Inst J"},{"key":"B3","doi-asserted-by":"publisher","first-page":"526","DOI":"10.1016\/j.athoracsur.2006.06.080","article-title":"Surgical treatment of postinfarction left ventricular pseudoaneurysm","volume":"83","author":"Atik","year":"2007","journal-title":"Ann Thorac Surg"},{"key":"B4","doi-asserted-by":"publisher","first-page":"553","DOI":"10.1016\/S0003-4975(00)01412-0","article-title":"Surgical treatment of acquired left ventricular pseudoaneurysms","volume":"70","author":"Pretre","year":"2000","journal-title":"Ann Thorac Surg"},{"key":"B5","doi-asserted-by":"publisher","first-page":"e62","DOI":"10.1136\/hrt.2004.042135","article-title":"Percutaneous device closure of a pseudoaneurysm of the left ventricular wall","volume":"90","author":"Clift","year":"2004","journal-title":"Heart"},{"key":"B6","doi-asserted-by":"publisher","first-page":"322","DOI":"10.1161\/CIRCINTERVENTIONS.111.962464","article-title":"Percutaneous closure of left ventricular pseudoaneurysm","volume":"4","author":"Dudiy","year":"2011","journal-title":"Circ Cardiovasc Interv"},{"key":"B7","doi-asserted-by":"publisher","first-page":"456","DOI":"10.1007\/s11886-013-0456-1","article-title":"Guidance of post myocardial infarction ventricular septal defect and pseudoaneurysm closure","volume":"16","author":"Kronzon","year":"2014","journal-title":"Curr Cardiol Rep"},{"key":"B8","doi-asserted-by":"publisher","first-page":"115.e1","DOI":"10.1016\/j.repc.2015.06.013","article-title":"Transcatheter device closure of pseudoaneurysms of the left ventricular wall: an emerging therapeutic option","volume":"35","author":"Madan","year":"2016","journal-title":"Rev Port Cardiol"},{"key":"B9","first-page":"E111","article-title":"Transcatheter closure of left ventricular pseudoaneurysm","volume":"24","author":"Acharya","year":"2012","journal-title":"J Invasive Cardiol"},{"key":"B10","doi-asserted-by":"publisher","first-page":"2113","DOI":"10.1111\/jocs.15407","article-title":"Percutaneous closure of left ventricular pseudoaneurysm in a patient with concomitant true left ventricular aneurysm","volume":"36","author":"Cavalcanti","year":"2021","journal-title":"J Card Surg"},{"key":"B11","doi-asserted-by":"publisher","first-page":"e123","DOI":"10.1016\/j.athoracsur.2019.12.019","article-title":"Transcatheter closure of left ventricular pseudoaneurysm after mitral valve replacement","volume":"110","author":"Arnaz","year":"2020","journal-title":"Ann Thorac Surg"},{"key":"B12","doi-asserted-by":"publisher","first-page":"569","DOI":"10.1016\/j.jaccas.2019.08.019","article-title":"Left ventricular pseudoaneurysm complicated with very late rupture 5 years after myocardial infarction","volume":"1","author":"Al Saidi","year":"2019","journal-title":"JACC Case Rep"}],"container-title":["Frontiers in Cardiovascular Medicine"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fcvm.2026.1879721\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T05:52:58Z","timestamp":1784699578000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fcvm.2026.1879721\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,22]]},"references-count":12,"alternative-id":["10.3389\/fcvm.2026.1879721"],"URL":"https:\/\/doi.org\/10.3389\/fcvm.2026.1879721","relation":{},"ISSN":["2297-055X"],"issn-type":[{"value":"2297-055X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,22]]},"article-number":"1879721"}}