{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T04:59:05Z","timestamp":1790657945641,"version":"4.1.0"},"reference-count":13,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T00:00:00Z","timestamp":1790640000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Cardiovasc. Med."],"abstract":"\n Background<\/jats:title>\n This study aimed to compare the perioperative and early-to-mid-term outcomes of hybrid coronary revascularization (HCR) and minimally invasive multivessel coronary artery bypass grafting (MICS-CABG) for treating multivessel coronary artery disease (MVCAD).<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n We conducted a retrospective observational cohort study including MVCAD patients who underwent HCR or MICS-CABG at Ruijin Hospital between January 2019 and December 2024. The primary endpoint was the incidence of major perioperative complications within 30 days after surgery, including all-cause mortality, myocardial infarction (MI), and stroke. Secondary endpoints included 1-year all-cause survival and 1-year graft or target-vessel patency. Propensity score matching (PSM) was performed to reduce baseline imbalance between the two groups. Kaplan\u2013Meier analyses were used to evaluate 1-year survival.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n A total of 169 patients were included, of whom 91 underwent HCR and 78 underwent MICS-CABG. After 1:1 PSM, 132 patients remained, with 66 patients in each group. Major perioperative complications within 30 days after surgery were comparable. In the HCR group, MI occurred in 1 patient (1.52% vs. 0.00%;\n P<\/jats:italic>\n \u2009=\u20091.000), stroke in 2 patients (3.03% vs. 0.00%;\n P<\/jats:italic>\n \u2009=\u20090.476), and death in 1 patient (1.52% vs. 0.00%;\n P<\/jats:italic>\n \u2009=\u20091.000), whereas no such events occurred in the MICS-CABG group. The MICS-CABG group had significantly longer operative time (250 vs. 160\u2005min,\n P<\/jats:italic>\n \u2009&lt;\u20090.001) and greater 24-hour postoperative drainage (420 vs. 185\u2005mL,\n P<\/jats:italic>\n \u2009&lt;\u20090.001). Postoperative respiratory complications were numerically more frequent after MICS-CABG. The 1-year survival rate was comparable between the HCR and MICS-CABG groups after PSM (98.5% vs. 98.4%; log-rank\n P<\/jats:italic>\n \u2009=\u20090.996). The 1-year left anterior descending artery (LAD) revascularization patency rate was comparable between the HCR and MICS-CABG groups (94.6% vs. 90.0%;\n P<\/jats:italic>\n \u2009=\u20090.366), as was non-LAD target-vessel patency (86.5% vs. 87.0%;\n P<\/jats:italic>\n \u2009=\u20090.922).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n HCR and MICS-CABG provided comparable perioperative safety, early-to-mid-term survival, and 1-year revascularization patency in selected patients with MVCAD. Treatment strategy may be individualized according to coronary lesion characteristics and cardiopulmonary function.<\/jats:p>\n <\/jats:sec>","DOI":"10.3389\/fcvm.2026.1887132","type":"journal-article","created":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T04:40:18Z","timestamp":1790656818000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Comparison of hybrid coronary revascularization and minimally invasive multivessel CABG for multivessel coronary artery disease"],"prefix":"10.3389","volume":"13","author":[{"given":"Ting","family":"Ren","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Surgery, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine","place":["Shanghai, China"]},{"name":"Department of Cardiovascular Surgery, Beijing Anzhen Hospital, Capital Medical University","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haoyi","family":"Yao","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine","place":["Shanghai, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhaohui","family":"Cheng","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine","place":["Shanghai, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zibo","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine","place":["Shanghai, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiapei","family":"Qiu","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine","place":["Shanghai, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiang","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine","place":["Shanghai, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,9,29]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1093\/eurheartj\/ehy394","article-title":"2018 ESC\/EACTS guidelines on myocardial revascularization","volume":"40","author":"Neumann","year":"2019","journal-title":"Eur Heart J"},{"key":"B2","doi-asserted-by":"publisher","first-page":"S78","DOI":"10.1161\/CIRCULATIONAHA.108.840041","article-title":"Minimally invasive coronary artery bypass grafting: dual-center experience in 450 consecutive patients","volume":"120","author":"McGinn","year":"2009","journal-title":"Circulation"},{"key":"B3","doi-asserted-by":"publisher","first-page":"585","DOI":"10.1016\/j.ahj.2014.01.006","article-title":"Clinical outcomes after hybrid coronary revascularization versus coronary artery bypass surgery: a meta-analysis of 1,190 patients","volume":"167","author":"Harskamp","year":"2014","journal-title":"Am Heart J"},{"key":"B4","doi-asserted-by":"publisher","first-page":"96","DOI":"10.1016\/j.xjon.2025.03.030","article-title":"Minimally invasive coronary bypass grafting for treating multivessel coronary disease: a single-center prospective pilot study","volume":"25","author":"Ding","year":"2025","journal-title":"JTCVS Open"},{"key":"B5","doi-asserted-by":"publisher","first-page":"e11941","DOI":"10.1097\/MD.0000000000011941","article-title":"Hybrid coronary revascularization versus conventional coronary artery bypass grafting: systematic review and meta-analysis","volume":"97","author":"Reynolds","year":"2018","journal-title":"Medicine (Baltimore)"},{"key":"B6","doi-asserted-by":"publisher","first-page":"402","DOI":"10.1016\/j.atssr.2024.10.024","article-title":"Minimally invasive vs conventional coronary bypass surgery for multivessel coronary disease","volume":"3","author":"Gong","year":"2025","journal-title":"Ann Thorac Surg Short Rep"},{"key":"B7","doi-asserted-by":"publisher","first-page":"773","DOI":"10.1016\/S0022-5223(19)36000-3","article-title":"Coronary bypass graft fate. Angiographic study of 1,179 vein grafts early, one year, and five years after operation","volume":"91","author":"FitzGibbon","year":"1986","journal-title":"J Thorac Cardiovasc Surg"},{"key":"B8","doi-asserted-by":"publisher","first-page":"302","DOI":"10.1213\/ANE.0000000000000808","article-title":"Lung injury after one-lung ventilation: a review of the pathophysiologic mechanisms affecting the ventilated and the collapsed lung","volume":"121","author":"Lohser","year":"2015","journal-title":"Anesth Analg"},{"key":"B9","doi-asserted-by":"publisher","first-page":"889","DOI":"10.1007\/s00408-020-00405-7","article-title":"Pulmonary complications of cardiac surgery","volume":"198","author":"Tanner","year":"2020","journal-title":"Lung"},{"key":"B10","doi-asserted-by":"publisher","first-page":"360","DOI":"10.1016\/j.jtcvs.2017.02.054","article-title":"Apneic oxygen insufflation decreases the incidence of hypoxemia during one-lung ventilation in open and thoracoscopic pulmonary lobectomy: a randomized controlled trial","volume":"154","author":"Jung","year":"2017","journal-title":"J Thorac Cardiovasc Surg"},{"key":"B11","doi-asserted-by":"publisher","first-page":"317","DOI":"10.1093\/bja\/aex002","article-title":"Postoperative pulmonary complications","volume":"118","author":"Miskovic","year":"2017","journal-title":"Br J Anaesth"},{"key":"B12","doi-asserted-by":"publisher","first-page":"484","DOI":"10.1016\/j.athoracsur.2013.08.041","article-title":"Clinical and angiographic results after hybrid coronary revascularization","volume":"97","author":"Halkos","year":"2014","journal-title":"Ann Thorac Surg"},{"key":"B13","doi-asserted-by":"publisher","first-page":"203","DOI":"10.1016\/j.jtcvs.2013.09.016","article-title":"Results of the minimally invasive coronary artery bypass grafting angiographic patency study","volume":"147","author":"Ruel","year":"2014","journal-title":"J Thorac Cardiovasc Surg"}],"container-title":["Frontiers in Cardiovascular Medicine"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fcvm.2026.1887132\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T04:40:23Z","timestamp":1790656823000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fcvm.2026.1887132\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,29]]},"references-count":13,"alternative-id":["10.3389\/fcvm.2026.1887132"],"URL":"https:\/\/doi.org\/10.3389\/fcvm.2026.1887132","relation":{},"ISSN":["2297-055X"],"issn-type":[{"value":"2297-055X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,29]]},"article-number":"1887132"}}