{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T12:21:44Z","timestamp":1788524504151,"version":"build-2803163510"},"reference-count":21,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T00:00:00Z","timestamp":1788480000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Cardiovasc. Med."],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Transcatheter Tricuspid Valve Replacement (TTVR) has emerged as a treatment option for patients with severe tricuspid regurgitation (TR) who are at high surgical risk and unsuitable for tricuspid transcatheter edge-to-edge repair (T-TEER).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>This study aims to compare procedural, clinical and echocardiographic outcomes of two different TTVR devices: the Cardiovalve (Venus MedTech) and the EVOQUE (Edwards Lifesciences) prosthesis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We performed a retrospective, single-center cohort analysis including all consecutive patients who were treated with TTVR. Primary endpoints included TR reduction, NYHA class and safety events according to TVARC criteria.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Overall, 25 consecutive patients were included in the analysis. The Cardiovalve prosthesis was implanted in 12 patients and the EVOQUE prosthesis in 13 patients. Intraprocedural success was 100%. There was a significant reduction in TR grade (4.20 vs. 0.48;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&amp;lt;\u20090.001) and NYHA class (2.72 vs. 1.88;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.004) for the overall cohort at 30-day follow-up, but no differences between the two devices (TR grade 0.50 vs. 0.46;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.408 and NYHA class 1.75 vs. 2.00;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.813; Cardiovalve and EVOQUE respectively). Mortality rate at 30 days was 0% in both groups. One patient in each group (8.0%) required new pacemaker implantation.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>TTVR with both, the Cardiovalve and EVOQUE prothesis is an effective treatment option, leading to profound TR reduction and meaningful clinical improvement at 30-day follow-up. Patient selection and long term follow up need to be the focus of future studies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fcvm.2026.1923052","type":"journal-article","created":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T12:08:46Z","timestamp":1788523726000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Transcatheter tricuspid valve replacement\u2014a comparison of clinical and procedural outcomes of two different prostheses"],"prefix":"10.3389","volume":"13","author":[{"given":"Florian","family":"Genske","sequence":"first","affiliation":[{"name":"Department of Cardiology, University Hospital Schleswig-Holstein, University Heart Center L\u00fcbeck","place":["L\u00fcbeck, Germany"]},{"name":"DZHK (German Centre for Cardiovascular Research), Partner Site North","place":["L\u00fcbeck, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Judith","family":"Heine","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Asklepios Clinic Hamburg-Rissen","place":["Hamburg, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christoph","family":"Marquetand","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University Hospital Schleswig-Holstein, University Heart Center L\u00fcbeck","place":["L\u00fcbeck, Germany"]},{"name":"DZHK (German Centre for Cardiovascular Research), Partner Site North","place":["L\u00fcbeck, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Stiermaier","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University Hospital Schleswig-Holstein, University Heart Center L\u00fcbeck","place":["L\u00fcbeck, Germany"]},{"name":"DZHK (German Centre for Cardiovascular Research), Partner Site North","place":["L\u00fcbeck, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ingo","family":"Eitel","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University Hospital Schleswig-Holstein, University Heart Center L\u00fcbeck","place":["L\u00fcbeck, Germany"]},{"name":"DZHK (German Centre for Cardiovascular Research), Partner Site North","place":["L\u00fcbeck, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Frerker","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University Hospital Schleswig-Holstein, University Heart Center L\u00fcbeck","place":["L\u00fcbeck, Germany"]},{"name":"DZHK (German Centre for Cardiovascular Research), Partner Site North","place":["L\u00fcbeck, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tobias","family":"Schmidt","sequence":"additional","affiliation":[{"name":"DZHK (German Centre for Cardiovascular 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