{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T06:05:28Z","timestamp":1784786728154,"version":"3.55.0"},"reference-count":18,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T00:00:00Z","timestamp":1784764800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Digit. Health"],"abstract":"<jats:p>\n                    Patients facing cancer diagnoses must navigate fragmented information spanning prognosis, clinical research opportunities, and genomics-informed therapy. CancerStop.dev is a React-based web platform that consolidates trusted public resources into a single patient-centered interface to support informed decision-making. The platform\u2019s built-in\n                    <jats:italic>ComboReg<\/jats:italic>\n                    module presents interactive relative survival estimates up to 10 years after diagnosis by modeling (combined regression)\n                    <jats:italic>age-at-diagnosis<\/jats:italic>\n                    and\n                    <jats:italic>stage-at-diagnosis<\/jats:italic>\n                    using publicly available data from the SEER Program. Users can adjust an age slider and view stage-specific curves, enabling individualized and comprehensible visualizations of survivorship trends. A\n                    <jats:italic>Clinical Trials<\/jats:italic>\n                    module links directly to ClinicalTrials.gov, providing context-aware queries and free-form keyword filtering (e.g., mutations, investigational agents) to surface ongoing studies. The\n                    <jats:italic>Genes &amp;amp; More<\/jats:italic>\n                    module connects to NCBI ClinVar for variant-level insights, facilitating precision medicine exploration when genetic testing results are available. An\n                    <jats:italic>Approved Drugs<\/jats:italic>\n                    module routes to the National Cancer Institute resources listing FDA-approved agents relevant to specific cancers, aiding therapy literacy. A curated search tool (\n                    <jats:italic>PresciQure<\/jats:italic>\n                    ) complements these features by streamlining access to the biomedical literature, package inserts of FDA-approved drugs, and related oncology resources. The platform is non-prescriptive, emphasizes transparency regarding data provenance and limitations, and is positioned to incorporate additional cancer types, demographic stratifications, and multi-omic resources. CancerStop.dev aims to empower patients, caregivers, and clinicians with timely, integrated, and navigable information, thereby strengthening their advocacy and encouraging participation in research and precision care.\n                  <\/jats:p>","DOI":"10.3389\/fdgth.2026.1788996","type":"journal-article","created":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T05:37:36Z","timestamp":1784785056000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["CancerStop.dev: an interactive web platform integrating prognostic data, clinical trials, and genomic resources for patient empowerment"],"prefix":"10.3389","volume":"8","author":[{"given":"Vedanth","family":"Ramji","sequence":"first","affiliation":[{"name":"Queromatics","place":["Laveen, AZ, United States"]},{"name":"Stanford University","place":["Stanford, CA, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baladithya","family":"Muralitharan","sequence":"additional","affiliation":[{"name":"Queromatics","place":["Laveen, AZ, United States"]},{"name":"Boston University","place":["Boston, MA, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ganeshram","family":"Janakiraman","sequence":"additional","affiliation":[{"name":"Queromatics","place":["Laveen, AZ, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natarajan","family":"Ganesan","sequence":"additional","affiliation":[{"name":"Queromatics","place":["Laveen, AZ, United States"]},{"name":"Department of Biomedical and Anatomical Sciences, New York Institute of Technology College of Osteopathic Medicine","place":["Jonesboro, AR, United 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