{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T14:57:14Z","timestamp":1779893834932,"version":"3.53.1"},"reference-count":64,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2023,4,27]],"date-time":"2023-04-27T00:00:00Z","timestamp":1682553600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Dent. Med"],"abstract":"<jats:sec><jats:title>Aims<\/jats:title><jats:p>The aims of this study were to (1) evaluate oral health-related quality of life (OHRQoL) in 8\u201312-year-old Costa Rican schoolchildren before and after dental treatment and (2) collect clinical and sociodemographic characteristics.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Schoolchildren completed the Child Oral Health Impact Profile-Short Form (COHIP-SF-19) questionnaire before and after dental treatment. One of the parents was asked to complete a sociodemographic survey. Patients were treated for caries, hypomineralizations, and dental malocclusions. The prevalence of these conditions was assessed from the patient's electronic dental record.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Eighty participants (39 male and 41 female, average age: 9.4\u2009\u00b1\u20091.0 years) were recruited. The prevalence of dental caries was 56.1% with a mean deft and DMFT score of 3.15\u2009\u00b1\u20090.96 and 2.22\u2009\u00b1\u20090.77, respectively. The prevalence of hypomineralization and dental malocclusions was 53.7% and 82.9%, respectively. The Simplified Oral Hygiene Index before treatment was 1.45\u2009\u00b1\u20090.45 and after was 1.42\u2009\u00b1\u20090.43. The mean COHIP-SF-19 total score decreased from 53.7\u2009\u00b1\u20097.8 before dental treatment to 31.4\u2009\u00b1\u20094.2 after treatment. Improvements in all subdomains were also observed. Regarding sociodemographic characteristics, 65% of the patients lived in San Jos\u00e9, Costa Rica's capital city, and 56.3% of the studied population belonged to a low-income family. Most parents did not complete high school. Regarding the number of family members living in the same house as the patient, an average of four people was reported. In relation to family structure, 58.8% of the children's parents lived together, either married or free union. As for household ownership, 53.8% of parents reported owning their house, 36.3% lived in a rented house, and 10% lived in a borrowed home.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The prevalence of caries, hypomineralizations, and dental malocclusions were high before dental treatment. Reported sociodemographic characteristics unlikely changed after dental treatment, suggesting dental care played a pivotal role in improving self-perceptions of oral health and quality of life in our clinical setting.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fdmed.2023.1167845","type":"journal-article","created":{"date-parts":[[2023,4,27]],"date-time":"2023-04-27T05:27:17Z","timestamp":1682573237000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":2,"title":["Changes in oral health-related quality of life before and after dental treatment in 8\u201312-year-old Costa Rican schoolchildren"],"prefix":"10.3389","volume":"4","author":[{"given":"Juliana","family":"Jim\u00e9nez-Lobo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela","family":"Batista-C\u00e1rdenas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ariadna","family":"Aguilar-Cubillo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adri\u00e1n","family":"G\u00f3mez-Fern\u00e1ndez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karol","family":"Ram\u00edrez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2023,4,27]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1186\/1472-6831-5-7","article-title":"Pilot survey of oral health-related quality of life: a cross-sectional study of adults in Benin City, Edo State, Nigeria","volume":"5","author":"Okunseri","year":"2005","journal-title":"BMC Oral Health"},{"key":"B2","doi-asserted-by":"publisher","first-page":"100040","DOI":"10.1016\/j.adoms.2021.100040","article-title":"Assessing the impact of an urgent dental care centre on the oral health-related quality of life of patients during the COVID-19 pandemic","volume":"2","author":"Pajpani","year":"2021","journal-title":"Adv Oral Maxillofac Surg"},{"key":"B3","doi-asserted-by":"publisher","first-page":"216","DOI":"10.1111\/cdoe.12279","article-title":"Oral health-related quality-of-life scores differ by socioeconomic status and caries experience","volume":"45","author":"Chaffee","year":"2017","journal-title":"Community Dent Oral Epidemiol"},{"key":"B4","doi-asserted-by":"publisher","first-page":"126","DOI":"10.1186\/1477-7525-8-126","article-title":"Tooth loss and oral health- related quality of life: a systematic review and meta-analysis","volume":"5","author":"Gerritsen","year":"2010","journal-title":"Health Qual Life Outcomes"},{"key":"B5","doi-asserted-by":"publisher","first-page":"1264","DOI":"10.1177\/0022034511399918","article-title":"Oral health-related quality of life: what, why, how, and future implications","volume":"90","author":"Sischo","year":"2011","journal-title":"J Dent Res"},{"key":"B6","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1159\/000351693","article-title":"An overview of children\u2019s oral health-related quality of life assessment: from scale development to measuring outcomes","volume":"47","author":"Genderson","year":"2013","journal-title":"Caries Res"},{"key":"B7","doi-asserted-by":"publisher","first-page":"45","DOI":"10.14693\/jdi.v28i1.1247","article-title":"An indonesian version of child oral health impact profile-short form 19 (COHIP-SF19): assessing validity and reliability","volume":"28","author":"Nuraini","year":"2021","journal-title":"J Dent Indones"},{"key":"B8","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1186\/1472-6831-14-40","article-title":"Assessment of the quality of measures of child oral health-related quality of life","volume":"23","author":"Gilchrist","year":"2014","journal-title":"BMC Oral Health"},{"key":"B9","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1111\/j.1600-0528.2007.00404.x","article-title":"Concurrent validity of the COHIP","volume":"35","author":"Dunlow","year":"2007","journal-title":"Community Dent Oral Epidemiol"},{"key":"B10","doi-asserted-by":"publisher","first-page":"302","DOI":"10.1111\/j.1752-7325.2012.00338.x","article-title":"Reliability, and validity testing for the child oral health impact profile-reduced (COHIP-SF 19)","volume":"72","author":"Broder","year":"2012","journal-title":"J Public Health Dent"},{"key":"B11","doi-asserted-by":"publisher","first-page":"224","DOI":"10.1186\/s12955-020-01469-y","article-title":"The development, validation, and psychometric properties of the Japanese version of the child oral health impact profile-short form 19 (COHIP-SF 19) for school-age children","volume":"18","author":"Minamidate","year":"2020","journal-title":"Health Qual Life Outcomes"},{"key":"B12","doi-asserted-by":"publisher","first-page":"35","DOI":"10.4034\/PBOCI.2016.161.04","article-title":"Sociodemographic factors and oral health conditions related to the impact on the quality of life of adolescents","volume":"16","author":"Kozmhinsky","year":"2016","journal-title":"Pesqui Bras Odontopediatria Cl\u00edn Integr"},{"key":"B13","doi-asserted-by":"publisher","first-page":"e0035","DOI":"10.1590\/pboci.2021.147","article-title":"Association between dental caries experience and socioeconomic determinants on oral health-related quality of life among children and their families","volume":"21","author":"Carvalho","year":"2021","journal-title":"Pesqui Bras Odontopediatria Cl\u00edn Integr"},{"key":"B14","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1111\/j.1752-7325.2007.00036.x","article-title":"Oral health-related quality of life of children by dental caries and fluorosis experience","volume":"67","author":"Do","year":"2007","journal-title":"J Public Health Dent"},{"key":"B15","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1186\/s12955-017-0729-2","article-title":"The factors that influence the oral health-related quality of life in 12-year-old children: baseline study of a longitudinal research","volume":"15","author":"Sun","year":"2017","journal-title":"Health Qual Life Outcomes"},{"key":"B16","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1590\/1980-549720200051","article-title":"Gingivitis influences oral health-related quality of life in adolescents: findings from a cohort study","volume":"23","author":"Ortiz","year":"2020","journal-title":"Rev Bras Epidemiol"},{"key":"B17","doi-asserted-by":"publisher","first-page":"1177","DOI":"10.4103\/jfmpc.jfmpc_956_19","article-title":"Association of gingivitis with children oral health-related quality of life in lucknow: a cross-sectional study","volume":"9","author":"Singh","year":"2020","journal-title":"J Family Med Prim Care"},{"key":"B18","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1111\/j.1600-0528.2012.00705.x","article-title":"Relationships between oral diseases and impacts on Thai schoolchildren\u2019s quality of life: evidence from a Thai national oral health survey of 12- and 15-year-olds","volume":"40","author":"Krisdapong","year":"2012","journal-title":"Community Dent Oral Epidemiol"},{"key":"B19","doi-asserted-by":"publisher","first-page":"595","DOI":"10.1093\/eurpub\/ckp179","article-title":"Prevalence and determinants of oral impacts on daily performance: results from a survey among school children in Italy","volume":"20","author":"Bianco","year":"2010","journal-title":"Eur J Public Health"},{"key":"B20","doi-asserted-by":"publisher","first-page":"283","DOI":"10.4274\/meandros.96158","article-title":"Evaluation of changes in quality of life after dental treatment in children","volume":"19","author":"Ulu G\u00fczel","year":"2018","journal-title":"Meandros Med Dental J"},{"key":"B21","doi-asserted-by":"publisher","first-page":"6449","DOI":"10.1007\/s00784-021-03947-z","article-title":"Changes in oral health-related quality of life after treatment of hypersensitive molar incisor hypomineralization-affected molars with a sealing","volume":"25","author":"Bekes","year":"2021","journal-title":"Clin Oral Investig"},{"key":"B22","doi-asserted-by":"publisher","first-page":"222","DOI":"10.1016\/j.jobcr.2019.05.005","article-title":"Factors associated with Oral Health Related Quality of Life of children with severe -Early Childhood Caries","volume":"9","author":"Mansoori","year":"2019","journal-title":"J Oral Biol Craniofac Res"},{"key":"B23","doi-asserted-by":"publisher","first-page":"e576","DOI":"10.4317\/medoral.23549","article-title":"Oral health-related quality of life after dental treatment in patients with intellectual disability","volume":"25","author":"Rollon","year":"2020","journal-title":"Med Oral Patol Oral Cir Bucal"},{"key":"B24","first-page":"38","article-title":"Oral health-related quality of life in Colombian children with Molar-Incisor Hypomineralization","volume":"31","author":"Velandia","year":"2018","journal-title":"Acta Odontol Latinoam"},{"key":"B25","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1590\/1807-3107BOR-2015.vol29.0076","article-title":"Molar incisor hypomineralization (MIH): conservative treatment management to restore affected teeth","volume":"29","author":"Fragelli","year":"2015","journal-title":"Braz Oral Res"},{"key":"B26","doi-asserted-by":"publisher","first-page":"324","DOI":"10.17796\/1053-4625-43.5.4","article-title":"Impact of molar incisor hypomineralization on oral health-related quality of life in Mexican schoolchildren","volume":"43","author":"Guti\u00e9rrez","year":"2019","journal-title":"J Clin Pediatr Dent"},{"key":"B27","doi-asserted-by":"publisher","first-page":"1753","DOI":"10.1007\/s00784-021-04150-w","article-title":"Impact of molar incisor hypomineralization on oral health\u2013related quality of life in 8\u201310-year-old children","volume":"26","author":"Joshi","year":"2022","journal-title":"Clin Oral Investig"},{"key":"B28","doi-asserted-by":"publisher","first-page":"5205","DOI":"10.1007\/s00784-021-03828-5","article-title":"Influence of caries and molar incisor hypomineralization on oral health-related quality of life in children","volume":"25","author":"Michaelis","year":"2021","journal-title":"Clin Oral Investig"},{"key":"B29","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1186\/1477-7525-10-6","article-title":"The influence of oral health conditions, socioeconomic status and home environment factors on schoolchildren\u2019s self-perception of quality of life","volume":"10","author":"Paula","year":"2012","journal-title":"Health Qual Life Outcomes"},{"key":"B30","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1111\/cdoe.12616","article-title":"Socioeconomic status and oral health-related quality of life: a systematic review and meta-analysis","volume":"49","author":"Knorst","year":"2021","journal-title":"Community Dent Oral Epidemiol"},{"key":"B31","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1186\/1477-7525-12-41","article-title":"A systematic review of the impact of parental socio-economic status and home environment characteristics on children\u2019s oral health related quality of life","volume":"12","author":"Kumar","year":"2014","journal-title":"Health Qual Life Outcomes"},{"key":"B32","doi-asserted-by":"publisher","first-page":"489","DOI":"10.1186\/s12887-020-02371-8","article-title":"The association of oral health status, demographic characteristics, and socioeconomic determinants with oral health-related quality of life among children: a systematic review and meta-analysis","volume":"20","author":"Moghaddam","year":"2020","journal-title":"BMC Pediatr"},{"key":"B33","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1186\/1475-9276-12-89","article-title":"Ethnic and socio-economic disparities in oral health outcomes and quality of life among Sri Lankan preschoolers: a cross-sectional study","volume":"12","author":"Nanayakkara","year":"2013","journal-title":"Int J Equity Health"},{"key":"B34","doi-asserted-by":"publisher","first-page":"689","DOI":"10.1590\/0103-6440201300478","article-title":"Racial differences in oral health-related quality of life: a multilevel analysis in Brazilian children","volume":"26","author":"Emmanuelli","year":"2015","journal-title":"Braz Dent J"},{"key":"B35","doi-asserted-by":"publisher","first-page":"1783","DOI":"10.1007\/s11136-019-02159-z","article-title":"Ethnic background and children\u2019s oral health-related quality of life","volume":"28","author":"Van Meijeren-van Lunteren","year":"2019","journal-title":"Qual Life Res"},{"key":"B36","doi-asserted-by":"publisher","first-page":"348","DOI":"10.1111\/j.1600-0528.2006.00323.x","article-title":"Disparities in oral health-related quality of life in a population of Canadian children","volume":"35","author":"Locker","year":"2007","journal-title":"Community Dent Oral Epidemiol"},{"key":"B37","first-page":"24","article-title":"Uso de la versi\u00f3n en espa\u00f1ol del perfil de impacto en la salud oral-14 para evaluar el impacto del tratamiento dental en la calidad de vida relacionada a la salud oral entre costarricenses","volume":"12","author":"Utsman","year":"2016","journal-title":"Rev Cient Odontol"},{"key":"B38","doi-asserted-by":"publisher","first-page":"343","DOI":"10.15517\/ijds.2020.41983","article-title":"Oral health-related quality of life determinants in the elderly from a Costa Rican day center: findings of a pilot study","volume":"23","author":"Barboza","year":"2020","journal-title":"Odovtos Int J Dent Sci"},{"key":"B39","doi-asserted-by":"publisher","first-page":"87","DOI":"10.15517\/ijds.v0i0.22147","article-title":"Validation of an instrument to determine the level of satisfaction of patients rehabilitated with removable prosthesis","volume":"17","author":"Valverde","year":"2015","journal-title":"Odovtos Int J Dent Sci"},{"key":"B40","first-page":"33","article-title":"Perfil de la salud oral (OHIP-14) en pacientes de la cl\u00ednica U dental, con base en la incapacidad psicol\u00f3gica seg\u00fan el sexo","volume":"7","author":"Ugalde","year":"2014","journal-title":"iDental"},{"key":"B41","doi-asserted-by":"publisher","first-page":"7","DOI":"10.14219\/jada.archive.1964.0034","article-title":"The simplified oral hygiene index","volume":"68","author":"Greene","year":"1964","journal-title":"J Am Dent Assoc"},{"key":"B42","volume-title":"OECD Reviews of labor market and social policies: Costa Rica, OECD reviews of labor market and social policies","year":"2017"},{"key":"B43","doi-asserted-by":"publisher","first-page":"3429","DOI":"10.1007\/s11136-017-1679-1","article-title":"Social inequalities in children\u2019s oral health-related quality of life: the generation R study","volume":"26","author":"Kragt","year":"2017","journal-title":"Qual Life Res"},{"key":"B44","doi-asserted-by":"publisher","first-page":"220","DOI":"10.4103\/jiaphd.jiaphd_57_17","article-title":"Influence of socioeconomic status and home environmental factors on oral health-related quality of life among school children in north Bengaluru, India: a cross-sectional study","volume":"15","author":"Ahuja","year":"2017","journal-title":"J Indian Assoc Public Health Dent"},{"key":"B45","doi-asserted-by":"publisher","first-page":"323","DOI":"10.1111\/j.1600-0528.2012.00672.x","article-title":"The impact of dental caries and trauma in children on family quality of life","volume":"40","author":"Abanto","year":"2012","journal-title":"Community Dent Oral Epidemiol"},{"key":"B46","doi-asserted-by":"publisher","first-page":"98","DOI":"10.4103\/0976-237X.83069.","article-title":"The effect of early childhood caries on the quality of life of children and their parents","volume":"2","author":"Acharya","year":"2011","journal-title":"Contemp Clin Dent"},{"key":"B47","doi-asserted-by":"publisher","first-page":"10409","DOI":"10.3390\/ijerph191610409","article-title":"Hypomineralized Teeth and Their Impact on Oral-Health-Related Quality of Life in Primary School Children","volume":"19","author":"Reissenberger","year":"2022","journal-title":"Int J Environ Res Public Health"},{"key":"B48","doi-asserted-by":"publisher","first-page":"197","DOI":"10.1186\/s12955-015-0393-3","article-title":"Oral health-related quality of life before and after crown therapy in young patients with amelogenesis imperfecta","volume":"13","author":"Pousette Lundgren","year":"2015","journal-title":"Health Qual Life Outcomes"},{"key":"B49","doi-asserted-by":"publisher","first-page":"986","DOI":"10.2319\/101714-743.1","article-title":"Impact of malocclusion on oral health-related quality of life in young adults","volume":"85","author":"Chen","year":"2015","journal-title":"Angle Orthodontist"},{"key":"B50","doi-asserted-by":"publisher","first-page":"411","DOI":"10.3390\/children10020411","article-title":"The Effect of the Treatment of Severe Early Childhood Caries on Growth-Development and Quality of Life","volume":"10","author":"Bagis","year":"2023","journal-title":"Children"},{"key":"B51","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1186\/s12903-018-0552-0","article-title":"Effects of dental treatment and systemic disease on oral health-related quality of life in Korean pediatric patients","volume":"18","author":"Song","year":"2018","journal-title":"BMC Oral Health"},{"key":"B52","doi-asserted-by":"publisher","first-page":"292","DOI":"10.1111\/j.1365-263X.2011.01197.x","article-title":"Validation of a Korean version of the child oral health impact profile (COHIP) among 8- to 15-year-old school children","volume":"22","author":"Ahn","year":"2012","journal-title":"Int J Pediatr Dentistry"},{"key":"B53","doi-asserted-by":"publisher","first-page":"e2019342","DOI":"10.1590\/1984-0462\/2021\/39\/2019342","article-title":"Association between trouble sleeping and oral conditions among schoolchildren","volume":"39","author":"Moro","year":"2021","journal-title":"Rev Paul Pediatr"},{"key":"B54","doi-asserted-by":"publisher","first-page":"271","DOI":"10.1590\/1984-0462\/2021\/39\/2019342","article-title":"Sustainability of improvement in oral health-related quality of life in children after dental treatment","volume":"15","author":"Farsi","year":"2021","journal-title":"Patient Prefer Adherence"},{"key":"B55","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1111\/j.1600-0528.2005.00210.x","article-title":"What do children\u2019s global ratings of oral health and well-being measure?","volume":"33","author":"Jokovic","year":"2005","journal-title":"Community Dent Oral Epidemiol"},{"key":"B56","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1111\/j.1600-0528.2006.00326.x","article-title":"Do life- or school-satisfaction and self-esteem indicators explain the oral hygiene habits of schoolchildren?","volume":"35","author":"Honkala","year":"2007","journal-title":"Community Dent Oral Epidemiol"},{"key":"B57","doi-asserted-by":"publisher","first-page":"1359","DOI":"10.1007\/s11136-010-9692-7","article-title":"Impact of socioeconomic and clinical factors on child oral health-related quality of life (COHRQoL)","volume":"19","author":"Piovesan","year":"2010","journal-title":"Qual Life Res"},{"key":"B58","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1186\/1477-7525-7-43","article-title":"Psychometric properties of the Brazilian version of the child perceptions questionnaire (CPQ11\u201314)\u2014short forms","volume":"7","author":"Torres","year":"2009","journal-title":"Health Qual Life Outcomes"},{"key":"B59","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1186\/1472-6831-15-15","article-title":"The influence of normative and subjective oral health status on schoolchildren\u2019s happiness","volume":"15","author":"Tuchtenhagen","year":"2015","journal-title":"BMC Oral Health"},{"key":"B60","doi-asserted-by":"publisher","first-page":"1900","DOI":"10.2105\/AJPH.2010.200915","article-title":"Impact of poor oral health on children\u2019s school attendance and performance","volume":"101","author":"Jackson","year":"2011","journal-title":"Am J Public Health"},{"key":"B61","doi-asserted-by":"publisher","first-page":"7920973","DOI":"10.1155\/2018\/7920973.","article-title":"Impact of malocclusions on the oral health-related quality of life of early adolescents in Ndola, Zambia","volume":"2018","author":"Anthony","year":"2018","journal-title":"Int J Dent"},{"key":"B62","doi-asserted-by":"publisher","first-page":"358","DOI":"10.1186\/s12903-022-02370-4","article-title":"Validation of the French version of COHIP-SF-19 among 12-years children in New Caledonia","volume":"22","author":"Skandrani","year":"2022","journal-title":"BMC Oral Health"},{"key":"B63","doi-asserted-by":"publisher","first-page":"e12","DOI":"10.1590\/1807-3107bor-2021.vol35.0125","article-title":"Impact of dental treatment on the oral health-related quality of life of Brazilian schoolchildren","volume":"35","author":"Mendon\u00e7a","year":"2021","journal-title":"Braz Oral Res"},{"key":"B64","doi-asserted-by":"publisher","first-page":"37","DOI":"10.17796\/1053-4628-42.1.7","article-title":"Evaluation of oral health-related quality of life to assess dental treatment in preschool children with early childhood caries: a preliminary study","volume":"42","author":"Voll\u00fa","year":"2018","journal-title":"J Clin Pediatr Dent"}],"container-title":["Frontiers in Dental Medicine"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fdmed.2023.1167845\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,16]],"date-time":"2024-08-16T11:59:04Z","timestamp":1723809544000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fdmed.2023.1167845\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4,27]]},"references-count":64,"alternative-id":["10.3389\/fdmed.2023.1167845"],"URL":"https:\/\/doi.org\/10.3389\/fdmed.2023.1167845","relation":{},"ISSN":["2673-4915"],"issn-type":[{"value":"2673-4915","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,4,27]]},"article-number":"1167845"}}