{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T17:03:36Z","timestamp":1791306216696,"version":"4.3.1"},"reference-count":50,"publisher":"Frontiers Media SA","content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Endocrinol."],"DOI":"10.3389\/fendo.2017.00092","type":"journal-article","created":{"date-parts":[[2017,4,26]],"date-time":"2017-04-26T04:33:28Z","timestamp":1493181208000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":108,"title":["Hashimoto\u2019s Thyroiditis and Autoimmune Gastritis"],"prefix":"10.3389","volume":"8","author":[{"given":"Miriam","family":"Cellini","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Giulia","family":"Santaguida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Camilla","family":"Virili","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia","family":"Capriello","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nunzia","family":"Brusca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucilla","family":"Gargano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Centanni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2017,4,26]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"1374","DOI":"10.1136\/bmj.1.5342.1374","article-title":"Autoimmune phenomena in pernicious anaemia. Serological overlap with thyroiditis, thyrotoxicosis, and systemic lupus erythematosus","volume":"1","author":"Doniach","year":"1963","journal-title":"Br Med J"},{"key":"B2","doi-asserted-by":"publisher","first-page":"657","DOI":"10.3109\/00365521.2015.1019918","article-title":"Chronic gastritis","volume":"50","author":"Sipponen","year":"2015","journal-title":"Scand J Gastroenterol"},{"key":"B3","doi-asserted-by":"publisher","first-page":"529","DOI":"10.1038\/nrgastro.2013.101","article-title":"Autoimmune atrophic gastritis \u2013 pathogenesis, pathology and management","volume":"10","author":"Neumann","year":"2013","journal-title":"Nat Rev Gastroenterol Hepatol"},{"key":"B4","doi-asserted-by":"publisher","first-page":"1726","DOI":"10.1001\/archinte.159.15.1726","article-title":"Atrophic body gastritis in patients with autoimmune thyroid disease: an underdiagnosed association","volume":"159","author":"Centanni","year":"1999","journal-title":"Arch Intern Med"},{"key":"B5","doi-asserted-by":"publisher","first-page":"563","DOI":"10.3748\/wjg.14.563","article-title":"Artificial neural networks in the recognition of the presence of thyroid disease in patients with atrophic body gastritis","volume":"14","author":"Lahner","year":"2008","journal-title":"World J Gastroenterol"},{"key":"B6","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1530\/EJE-09-0044","article-title":"Polyglandular autoimmune syndromes","volume":"161","author":"Kahaly","year":"2009","journal-title":"Eur J Endocrinol"},{"key":"B7","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1210\/edrv.23.3.0466","article-title":"Autoimmune adrenal insufficiency and autoimmune polyendocrine syndromes: autoantibodies, autoantigens, and their applicability in diagnosis and disease prediction","volume":"23","author":"Betterle","year":"2002","journal-title":"Endocr Rev"},{"key":"B8","doi-asserted-by":"publisher","first-page":"1125","DOI":"10.1016\/j.autrev.2016.09.009","article-title":"The association of other autoimmune diseases in patients with autoimmune thyroiditis: review of the literature and report of a large series of patients","volume":"15","author":"Fallahi","year":"2016","journal-title":"Autoimmun Rev"},{"key":"B9","doi-asserted-by":"publisher","first-page":"1385","DOI":"10.1089\/thy.2010.0041","article-title":"Prevalence of parietal cell antibodies in a large cohort of patients with autoimmune thyroiditis","volume":"20","author":"Checchi","year":"2010","journal-title":"Thyroid"},{"key":"B10","doi-asserted-by":"publisher","first-page":"136","DOI":"10.1016\/j.amjmed.2007.09.025","article-title":"Occurrence and risk factors for autoimmune thyroid disease in patients with atrophic body gastritis","volume":"121","author":"Lahner","year":"2008","journal-title":"Am J Med"},{"key":"B11","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1007\/s00394-007-0657-8","article-title":"Iodine prophylaxis \u2013 the protective factor against stomach cancer in iodine deficient areas","volume":"46","author":"Go\u0142kowski","year":"2007","journal-title":"Eur J Nutr"},{"key":"B12","doi-asserted-by":"publisher","first-page":"222","DOI":"10.1177\/147323000503300210","article-title":"Gastric carcinoma and thyroid status","volume":"33","author":"Kandemir","year":"2005","journal-title":"J Int Med Res"},{"key":"B13","doi-asserted-by":"publisher","first-page":"640","DOI":"10.1111\/j.1365-2265.2007.03091.x","article-title":"Chronic unexplained anemia in isolated autoimmune thyroid disease or associated with autoimmune related disorders","volume":"68","author":"Sibilla","year":"2008","journal-title":"Clin Endocrinol (Oxf)"},{"key":"B14","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1007\/s12020-012-9814-9","article-title":"Thyroxine treatment: absorption, malabsorption, and novel therapeutic approaches","volume":"43","author":"Centanni","year":"2013","journal-title":"Endocrine"},{"key":"B15","doi-asserted-by":"publisher","first-page":"106","DOI":"10.1210\/er.2012-1036","article-title":"The Na+\/I- symporter (NIS): mechanism and medical impact","volume":"35","author":"Portulano","year":"2014","journal-title":"Endocr Rev"},{"key":"B16","first-page":"11","article-title":"Role of iodine in evolution and carcinogenesis of thyroid, breast and stomach","volume":"4","author":"Venturi","year":"2000","journal-title":"Adv Clin Path"},{"key":"B17","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1042\/bj3050059","article-title":"Thiocyanate, a plausible physiological electron donor of gastric peroxidase","volume":"305","author":"Das","year":"1995","journal-title":"Biochem J"},{"key":"B18","doi-asserted-by":"publisher","first-page":"106","DOI":"10.5230\/jgc.2013.13.2.106","article-title":"Goiter frequency is more strongly associated with gastric adenocarcinoma than urine iodine level","volume":"13","author":"Tabaeizadeh","year":"2013","journal-title":"J Gastric Cancer"},{"key":"B19","doi-asserted-by":"publisher","first-page":"391","DOI":"10.1016\/j.autrev.2014.01.007","article-title":"Hashimoto thyroiditis: clinical and diagnostic criteria","volume":"13","author":"Caturegli","year":"2014","journal-title":"Autoimmun Rev"},{"key":"B20","doi-asserted-by":"publisher","first-page":"174","DOI":"10.1016\/j.autrev.2014.10.016","article-title":"Autoimmune thyroid disorders","volume":"14","author":"Antonelli","year":"2015","journal-title":"Autoimmun Rev"},{"key":"B21","doi-asserted-by":"publisher","first-page":"686","DOI":"10.1111\/apt.13097","article-title":"Autoimmune gastritis in autoimmune thyroid disease","volume":"41","author":"Venerito","year":"2015","journal-title":"Aliment Pharmacol Ther"},{"key":"B22","doi-asserted-by":"publisher","first-page":"459","DOI":"10.1016\/j.autrev.2014.01.048","article-title":"Diagnosis and classification of autoimmune gastritis","volume":"13","author":"Toh","year":"2014","journal-title":"Autoimmun Rev"},{"key":"B23","doi-asserted-by":"publisher","first-page":"2646","DOI":"10.1056\/NEJMra021194","article-title":"Thyroiditis","volume":"348","author":"Pearce","year":"2003","journal-title":"N Engl J Med"},{"key":"B24","doi-asserted-by":"publisher","first-page":"R241","DOI":"10.1530\/EJE-14-0047","article-title":"Mechanisms in endocrinology: autoimmune thyroid disease: old and new players","volume":"170","author":"Effraimidis","year":"2014","journal-title":"Eur J Endocrinol"},{"key":"B25","first-page":"B5177","article-title":"Regulatory B and T cell responses in patients with autoimmune thyroid disease and healthy controls","volume":"63","author":"Kristensen","year":"2016","journal-title":"Dan Med J"},{"key":"B26","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1007\/s12016-010-8218-y","article-title":"Cutting edge issues in autoimmune gastritis","volume":"42","author":"Toh","year":"2012","journal-title":"Clin Rev Allergy Immunol"},{"key":"B27","doi-asserted-by":"publisher","first-page":"702","DOI":"10.1055\/s-0035-1548832","article-title":"The pathogenesis of Hashimoto\u2019s thyroiditis: further developments in our understanding","volume":"47","author":"Ajjan","year":"2015","journal-title":"Horm Metab Res"},{"key":"B28","doi-asserted-by":"publisher","first-page":"1031","DOI":"10.1016\/j.bpg.2014.10.005","article-title":"Chronic gastritis \u2013 an update","volume":"28","author":"Varbanova","year":"2014","journal-title":"Best Pract Res Clin Gastroenterol"},{"key":"B29","doi-asserted-by":"publisher","first-page":"613","DOI":"10.3748\/wjg.v20.i3.613","article-title":"Helicobacter pylori and autoimmune disease: cause or bystander","volume":"20","author":"Smyk","year":"2014","journal-title":"World J Gastroenterol"},{"key":"B30","doi-asserted-by":"publisher","first-page":"1147","DOI":"10.1084\/jem.20030530","article-title":"Molecular mimicry between Helicobacter pylori antigens and H+, K+ \u2013 adenosine triphosphatase in human gastric autoimmunity","volume":"198","author":"Amedei","year":"2003","journal-title":"J Exp Med"},{"key":"B31","doi-asserted-by":"publisher","first-page":"377","DOI":"10.1053\/gast.2001.21187","article-title":"H+\/K+-ATPase (proton pump) is the target autoantigen of Th1-type cytotoxic T cells in autoimmune gastritis","volume":"120","author":"D\u2019Elios","year":"2001","journal-title":"Gastroenterology"},{"key":"B32","doi-asserted-by":"publisher","first-page":"1259","DOI":"10.4049\/jimmunol.176.2.1259","article-title":"Thyrocytes responding to IFN-gamma are essential for development of lymphocytic spontaneous autoimmune thyroiditis and inhibition of thyrocyte hyperplasia","volume":"176","author":"Yu","year":"2006","journal-title":"J Immunol"},{"key":"B33","doi-asserted-by":"publisher","first-page":"953","DOI":"10.1210\/jc.2009-1719","article-title":"Increased circulating pro-inflammatory cytokines and Th17 lymphocytes in Hashimoto\u2019s thyroiditis","volume":"95","author":"Figueroa-Vega","year":"2010","journal-title":"J Clin Endocrinol Metab"},{"key":"B34","doi-asserted-by":"publisher","first-page":"405","DOI":"10.1111\/j.1365-2265.2004.02085.x","article-title":"Cellular immune responses in autoimmune thyroid disease","volume":"61","author":"Weetman","year":"2004","journal-title":"Clin Endocrinol (Oxf)"},{"key":"B35","doi-asserted-by":"publisher","first-page":"411","DOI":"10.1016\/j.clim.2013.10.001","article-title":"Th17\u2009cell plays a role in the pathogenesis of Hashimoto\u2019s thyroiditis in patients","volume":"149","author":"Li","year":"2013","journal-title":"Clin Immunol"},{"key":"B36","doi-asserted-by":"publisher","first-page":"148","DOI":"10.1111\/j.1365-2249.2011.04419.x","article-title":"Increased interleukin-4-positive lymphocytes in patients with Hashimoto\u2019s thyroiditis and concurrent non-endocrine autoimmune disorders","volume":"165","author":"Santaguida","year":"2011","journal-title":"Clin Exp Immunol"},{"key":"B37","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1016\/S0167-5699(98)80010-8","article-title":"Fas-FasL interactions: a common pathogenetic mechanism in organ-specific autoimmunity","volume":"19","author":"De Maria","year":"1998","journal-title":"Immunol Today"},{"key":"B38","doi-asserted-by":"publisher","first-page":"1673","DOI":"10.1182\/blood-2005-09-3534","article-title":"Variable hematologic presentation of autoimmune gastritis: age-related progression from iron deficiency to cobalamin depletion","volume":"107","author":"Hershko","year":"2006","journal-title":"Blood"},{"key":"B39","doi-asserted-by":"publisher","first-page":"357","DOI":"10.1080\/08916930410001705439","article-title":"Pernicious anemia","volume":"37","author":"Toh","year":"2004","journal-title":"Autoimmunity"},{"key":"B40","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1089\/thy.1991.1.241","article-title":"Localization of human thyroxine absorption","volume":"1","author":"Hays","year":"1991","journal-title":"Thyroid"},{"key":"B41","doi-asserted-by":"publisher","first-page":"1787","DOI":"10.1056\/NEJMoa043903","article-title":"Thyroxine in goiter, Helicobacter pylori infection, and chronic gastritis","volume":"354","author":"Centanni","year":"2006","journal-title":"N Engl J Med"},{"key":"B42","doi-asserted-by":"publisher","first-page":"10331","DOI":"10.3748\/wjg.v20.i30.10331","article-title":"Helicobacter pylori infection and drugs malabsorption","volume":"20","author":"Lahner","year":"2014","journal-title":"World J Gastroenterol"},{"key":"B43","doi-asserted-by":"publisher","first-page":"3905","DOI":"10.1210\/jc.2009-0860","article-title":"Timing of levothyroxine administration affects serum thyrotropin concentration","volume":"94","author":"Bach-Huynh","year":"2009","journal-title":"J Clin Endocrinol Metab"},{"key":"B44","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1016\/j.ejpb.2008.10.008","article-title":"A comparative pH-dissolution profile study of selected commercial levothyroxine products using inductively coupled plasma mass spectrometry","volume":"72","author":"Pabla","year":"2009","journal-title":"Eur J Pharm Biopharm"},{"key":"B45","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1007\/s12020-016-1035-1","article-title":"Liquid and softgel levothyroxine use in clinical practice: state of the art","volume":"54","author":"Virili","year":"2016","journal-title":"Endocrine"},{"key":"B46","doi-asserted-by":"publisher","first-page":"1103","DOI":"10.1517\/17425247.2014.918101","article-title":"The administration of l-thyroxine as soft gel capsule or liquid solution","volume":"11","author":"Vita","year":"2014","journal-title":"Expert Opin Drug Deliv"},{"key":"B47","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1517\/17425247.2014.918101","article-title":"Thyroxine softgel capsule in patients with gastric-related T4 malabsorption","volume":"49","author":"Santaguida","year":"2015","journal-title":"Endocrine"},{"key":"B48","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1186\/s12876-016-0439-y","article-title":"Reversible normalisation of serum TSH levels in patients with autoimmune atrophic gastritis who received l-T4 in tablet form after switching to an oral liquid formulation: a case series","volume":"24","author":"Fallahi","year":"2016","journal-title":"BMC Gastroenterol"},{"key":"B49","doi-asserted-by":"publisher","first-page":"e38","DOI":"10.4158\/EP13316.CR","article-title":"Tablet levothyroxine (l-T4) malabsorption induced by proton pump inhibitor; a problem that was solved by switching to l-T4 in soft gel capsule","volume":"20","author":"Vita","year":"2014","journal-title":"Endocr Pract"},{"key":"B50","doi-asserted-by":"publisher","first-page":"4481","DOI":"10.1210\/jc.2014-2684","article-title":"Switching levothyroxine from the tablet to the oral solution formulation corrects the impaired absorption of levothyroxine induced by proton-pump inhibitors","volume":"99","author":"Vita","year":"2014","journal-title":"J Clin Endocrinol Metab"}],"container-title":["Frontiers in Endocrinology"],"original-title":[],"link":[{"URL":"http:\/\/journal.frontiersin.org\/article\/10.3389\/fendo.2017.00092\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,5,11]],"date-time":"2017-05-11T15:16:57Z","timestamp":1494515817000},"score":1,"resource":{"primary":{"URL":"http:\/\/journal.frontiersin.org\/article\/10.3389\/fendo.2017.00092\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,4,26]]},"references-count":50,"alternative-id":["10.3389\/fendo.2017.00092"],"URL":"https:\/\/doi.org\/10.3389\/fendo.2017.00092","relation":{},"ISSN":["1664-2392"],"issn-type":[{"value":"1664-2392","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,4,26]]},"article-number":"92"}}