{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T06:44:08Z","timestamp":1790837048259,"version":"4.1.0"},"reference-count":63,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2019,1,18]],"date-time":"2019-01-18T00:00:00Z","timestamp":1547769600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Endocrinol."],"DOI":"10.3389\/fendo.2018.00818","type":"journal-article","created":{"date-parts":[[2019,1,18]],"date-time":"2019-01-18T12:41:27Z","timestamp":1547815287000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":47,"title":["The Benefits and Limits of Technological Advances in Glucose Management Around Physical Activity in Patients Type 1 Diabetes"],"prefix":"10.3389","volume":"9","author":[{"given":"S\u00e9mah","family":"Tagougui","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadine","family":"Taleb","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R\u00e9mi","family":"Rabasa-Lhoret","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2019,1,18]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"542","DOI":"10.1007\/s00125-011-2403-2","article-title":"What are the health benefits of physical activity in type 1 diabetes mellitus? A literature review","volume":"55","author":"Chimen","year":"2012","journal-title":"Diabetologia"},{"key":"B2","doi-asserted-by":"publisher","first-page":"2108","DOI":"10.2337\/dc08-0720","article-title":"Barriers to physical activity among patients with type 1 diabetes","volume":"31","author":"Brazeau","year":"2008","journal-title":"Diabetes Care"},{"key":"B3","doi-asserted-by":"publisher","first-page":"62","DOI":"10.1016\/j.jcjd.2013.08.268","article-title":"Lifestyle and cardiometabolic risk in adults with type 1 diabetes: a review","volume":"38","author":"Leroux","year":"2014","journal-title":"Can J Diabetes"},{"key":"B4","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1586\/eem.10.78","article-title":"Exercise-related hypoglycemia in diabetes mellitus","volume":"6","author":"Younk","year":"2011","journal-title":"Expert Rev Endocrinol Metab"},{"key":"B5","doi-asserted-by":"publisher","first-page":"377","DOI":"10.1016\/S2213-8587(17)30014-1","article-title":"Exercise management in type 1 diabetes: a consensus statement","volume":"5","author":"Riddell","year":"2017","journal-title":"Lancet Diabetes Endocrinol"},{"key":"B6","doi-asserted-by":"publisher","first-page":"1217","DOI":"10.1177\/1932296815609370","article-title":"Exercise and the development of the artificial pancreas: one of the more difficult series of hurdles","volume":"9","author":"Riddell","year":"2015","journal-title":"J Diabetes Sci Technol"},{"key":"B7","doi-asserted-by":"publisher","first-page":"1632","DOI":"10.1007\/s00125-016-3978-4","article-title":"Can somatostatin antagonism prevent hypoglycaemia during exercise in type 1 diabetes?","volume":"59","author":"Taleb","year":"2016","journal-title":"Diabetologia"},{"key":"B8","doi-asserted-by":"publisher","first-page":"427","DOI":"10.1016\/j.jcjd.2013.08.269","article-title":"Vigorous intensity exercise for glycemic control in patients with type 1 diabetes","volume":"37","author":"Yardley","year":"2013","journal-title":"Can J Diabetes"},{"key":"B9","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1249\/JSR.0000000000000327","article-title":"Update on management of type 1 diabetes and type 2 diabetes in athletes","volume":"16","author":"Yardley","year":"2017","journal-title":"Curr Sports Med Rep"},{"key":"B10","doi-asserted-by":"publisher","first-page":"e99","DOI":"10.1111\/sms.12202","article-title":"Impact of single and multiple sets of resistance exercise in type 1 diabetes","volume":"25","author":"Turner","year":"2015","journal-title":"Scand J Med Sci Sports"},{"key":"B11","doi-asserted-by":"crossref","first-page":"1736","DOI":"10.2337\/diacare.15.11.1736","article-title":"Fuel and fluid homeostasis during long-term exercise in healthy subjects and type I diabetic patients","volume":"15","author":"Koivisto","year":"1992","journal-title":"Diabetes Care"},{"key":"B12","doi-asserted-by":"publisher","first-page":"S58","DOI":"10.2337\/dc06-9910","article-title":"Physical activity\/exercise and diabetes","volume":"27","author":"American","year":"2004","journal-title":"Diabetes Care"},{"key":"B13","doi-asserted-by":"crossref","first-page":"1732","DOI":"10.2337\/diacare.15.11.1732","article-title":"Prevention of hypoglycemia during exercise in type I diabetes","volume":"15","author":"Kemmer","year":"1992","journal-title":"Diabetes Care"},{"key":"B14","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1016\/S1262-3636(07)70144-1","article-title":"A new table for prevention of hypoglycaemia during physical activity in type 1 diabetic patients","volume":"30","author":"Grimm","year":"2004","journal-title":"Diabetes Metab"},{"key":"B15","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1123\/ijsn.9.1.24","article-title":"Glucose ingestion matched with total carbohydrate utilization attenuates hypoglycemia during exercise in adolescents with IDDM","volume":"9","author":"Riddell","year":"1999","journal-title":"Int J Sport Nutr"},{"key":"B16","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1249\/MSS.0b013e3181e6d6a1","article-title":"Exercise and glycemic imbalances: a situation-specific estimate of glucose supplement","volume":"43","author":"Francescato","year":"2011","journal-title":"Med Sci Sports Exerc"},{"key":"B17","doi-asserted-by":"publisher","first-page":"1316","DOI":"10.2337\/diacare.26.4.1316","article-title":"Glucose response to intense aerobic exercise in type 1 diabetes: maintenance of near euglycemia despite a drastic decrease in insulin dose","volume":"26","author":"Mauvais-Jarvis","year":"2003","journal-title":"Diabetes Care"},{"key":"B18","doi-asserted-by":"publisher","first-page":"625","DOI":"10.2337\/diacare.24.4.625","article-title":"Guidelines for premeal insulin dose reduction for postprandial exercise of different intensities and durations in type 1 diabetic subjects treated intensively with a basal-bolus insulin regimen (ultralente-lispro)","volume":"24","author":"Rabasa-Lhoret","year":"2001","journal-title":"Diabetes Care"},{"key":"B19","doi-asserted-by":"publisher","first-page":"2293","DOI":"10.1001\/archinte.161.19.2293","article-title":"Continuous subcutaneous insulin infusion: a comprehensive review of insulin pump therapy","volume":"161","author":"Lenhard","year":"2001","journal-title":"Arch Intern Med"},{"key":"B20","doi-asserted-by":"publisher","first-page":"593","DOI":"10.2337\/diacare.25.3.593","article-title":"Continuous subcutaneous insulin infusion at 25 years: evidence base for the expanding use of insulin pump therapy in type 1 diabetes","volume":"25","author":"Pickup","year":"2002","journal-title":"Diabetes Care"},{"key":"B21","doi-asserted-by":"publisher","first-page":"389","DOI":"10.1517\/17425247.2016.1115013","article-title":"Continuous subcutaneous insulin infusion therapy and multiple daily insulin injections in type 1 diabetes mellitus: a comparative overview and future horizons","volume":"13","author":"Thabit","year":"2016","journal-title":"Expert Opin Drug Deliv"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD005103.pub2","article-title":"Continuous subcutaneous insulin infusion (CSII) versus multiple insulin injections for type 1 diabetes mellitus","author":"Misso","year":"2010","journal-title":"Cochr Database Syst Rev"},{"key":"B23","doi-asserted-by":"publisher","first-page":"1616","DOI":"10.1056\/NEJMct1113948","article-title":"Insulin-pump therapy for type 1 diabetes mellitus","volume":"366","author":"Pickup","year":"2012","journal-title":"N Engl J Med"},{"key":"B24","doi-asserted-by":"publisher","first-page":"1265","DOI":"10.1016\/S0140-6736(14)61037-0","article-title":"Insulin pump treatment compared with multiple daily injections for treatment of type 2 diabetes (OpT2mise): a randomised open-label controlled trial","volume":"384","author":"Reznik","year":"2014","journal-title":"Lancet"},{"key":"B25","doi-asserted-by":"publisher","first-page":"2217","DOI":"10.2337\/dc12-2467","article-title":"Large pre- and postexercise rapid-acting insulin reductions preserve glycemia and prevent early- but not late-onset hypoglycemia in patients with type 1 diabetes","volume":"36","author":"Campbell","year":"2013","journal-title":"Diabetes Care"},{"key":"B26","doi-asserted-by":"publisher","first-page":"1150","DOI":"10.1111\/dom.12552","article-title":"Insulin-based strategies to prevent hypoglycaemia during and after exercise in adult patients with type 1 diabetes on pump therapy: the DIABRASPORT randomized study","volume":"17","author":"Franc","year":"2015","journal-title":"Diabetes Obes Metab"},{"key":"B27","doi-asserted-by":"publisher","first-page":"370","DOI":"10.1089\/dia.2017.0010","article-title":"The effects of basal insulin suspension at the start of exercise on blood glucose levels during continuous versus circuit-based exercise in individuals with type 1 diabetes on continuous subcutaneous insulin infusion","volume":"19","author":"Zaharieva","year":"2017","journal-title":"Diabetes Technol Ther"},{"key":"B28","doi-asserted-by":"publisher","first-page":"e348","DOI":"10.1542\/peds.2004-2428","article-title":"Exercise with and without an insulin pump among children and adolescents with type 1 diabetes mellitus","volume":"116","author":"Admon","year":"2005","journal-title":"Pediatrics"},{"key":"B29","doi-asserted-by":"publisher","first-page":"2200","DOI":"10.2337\/dc06-0495","article-title":"Prevention of hypoglycemia during exercise in children with type 1 diabetes by suspending basal insulin","volume":"29","author":"Tsalikian","year":"2006","journal-title":"Diabetes Care"},{"key":"B30","doi-asserted-by":"publisher","first-page":"1437","DOI":"10.2337\/dc09-0595","article-title":"Changes in basal insulin infusion rates with subcutaneous insulin infusion: time until a change in metabolic effect is induced in patients with type 1 diabetes","volume":"32","author":"Heinemann","year":"2009","journal-title":"Diabetes Care"},{"key":"B31","doi-asserted-by":"publisher","DOI":"10.1016\/j.diabet.2018.08.002","article-title":"Timing of insulin basal rate reduction to reduce hypoglycemia during late post-prandial exercise in adults with type 1 diabetes using insulin pump therapy: a randomized crossover trial","author":"Roy-Fleming","year":"2018","journal-title":"Diabetes Metab"},{"key":"B32","doi-asserted-by":"publisher","first-page":"1636","DOI":"10.1007\/s00125-016-3981-9","article-title":"Insulin pump basal adjustment for exercise in type 1 diabetes: a randomised crossover study","volume":"59","author":"McAuley","year":"2016","journal-title":"Diabetologia"},{"key":"B33","doi-asserted-by":"publisher","first-page":"577","DOI":"10.1111\/dom.12232","article-title":"Are bedtime nutritional strategies effective in preventing nocturnal hypoglycaemia in patients with type 1 diabetes?","volume":"16","author":"Desjardins","year":"2014","journal-title":"Diabetes Obes Metab"},{"key":"B34","doi-asserted-by":"publisher","first-page":"784","DOI":"10.1016\/j.jpeds.2010.06.004","article-title":"Preventing post-exercise nocturnal hypoglycemia in children with type 1 diabetes","volume":"157","author":"Taplin","year":"2010","journal-title":"J Pediatr"},{"key":"B35","doi-asserted-by":"publisher","DOI":"10.2337\/dc18-1475","article-title":"Optimal insulin correction factor in post-high-intensity exercise hyperglycemia in adults with type 1 diabetes: the FIT study","author":"Aronson","year":"2018","journal-title":"Diabetes Care"},{"key":"B36","doi-asserted-by":"publisher","first-page":"952","DOI":"10.1177\/193229681100500419","article-title":"Efficacy of continuous glucose monitoring in improving glycemic control and reducing hypoglycemia: a systematic review and meta-analysis of randomized trials","volume":"5","author":"Gandhi","year":"2011","journal-title":"J Diabetes Sci Technol"},{"key":"B37","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1002\/dmrr.2557","article-title":"Efficacy of real-time continuous glucose monitoring on glycaemic control and glucose variability in type 1 diabetic patients treated with either insulin pumps or multiple insulin injection therapy: a randomized controlled crossover trial","volume":"31","author":"Tumminia","year":"2015","journal-title":"Diabetes Metab Res Rev"},{"key":"B38","doi-asserted-by":"publisher","first-page":"483","DOI":"10.1111\/dme.13561","article-title":"A randomized controlled pilot study of continuous glucose monitoring and flash glucose monitoring in people with Type 1 diabetes and impaired awareness of hypoglycaemia","volume":"35","author":"Reddy","year":"2018","journal-title":"Diabet Med"},{"key":"B39","doi-asserted-by":"publisher","first-page":"E73","DOI":"10.3390\/bios8030073","article-title":"Continuous glucose monitoring and exercise in type 1 diabetes: past, present and future","volume":"8","author":"Houlder","year":"2018","journal-title":"Biosensors"},{"key":"B40","doi-asserted-by":"publisher","first-page":"819","DOI":"10.1089\/dia.2011.0052","article-title":"Preventing exercise-induced hypoglycemia in type 1 diabetes using real-time continuous glucose monitoring and a new carbohydrate intake algorithm: an observational field study","volume":"13","author":"Riddell","year":"2011","journal-title":"Diabetes Technol Ther"},{"key":"B41","doi-asserted-by":"publisher","first-page":"531","DOI":"10.1089\/dia.2018.0079","article-title":"Continuous glucose monitoring and insulin informed advisory system with automated titration and dosing of insulin reduces glucose variability in type 1 diabetes mellitus","volume":"20","author":"Breton","year":"2018","journal-title":"Diabetes Technol Ther"},{"key":"B42","doi-asserted-by":"publisher","first-page":"619","DOI":"10.1016\/j.jcjd.2018.02.006","article-title":"We can work (It) out together: type 1 diabetes boot camp for adult patients and providers improves exercise self-efficacy","volume":"42","author":"Dyck","year":"2018","journal-title":"Can J Diabetes"},{"key":"B43","doi-asserted-by":"publisher","first-page":"258","DOI":"10.1016\/j.diabet.2012.12.004","article-title":"Accuracy assessment of online glucose monitoring by a subcutaneous enzymatic glucose sensor during exercise in patients with type 1 diabetes treated by continuous subcutaneous insulin infusion","volume":"39","author":"Radermecker","year":"2013","journal-title":"Diabetes Metab"},{"key":"B44","doi-asserted-by":"publisher","first-page":"46","DOI":"10.1089\/dia.2012.0182","article-title":"Point accuracy of interstitial continuous glucose monitoring during exercise in type 1 diabetes","volume":"15","author":"Yardley","year":"2013","journal-title":"Diabetes Technol Ther"},{"key":"B45","doi-asserted-by":"publisher","first-page":"561","DOI":"10.1089\/dia.2015.0394","article-title":"Comparison of two continuous glucose monitoring systems, dexcom G4 platinum and medtronic paradigm veo enlite system, at rest and during exercise","volume":"18","author":"Taleb","year":"2016","journal-title":"Diabetes Technol Ther"},{"key":"B46","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.diabres.2015.11.012","article-title":"Accuracy of continuous glucose monitoring during differing exercise conditions","volume":"112","author":"Bally","year":"2016","journal-title":"Diabetes Res Clin Pract"},{"key":"B47","doi-asserted-by":"publisher","first-page":"E489","DOI":"10.3390\/nu8080489","article-title":"Accuracy of continuous glucose monitoring (CGM) during continuous and high-intensity interval exercise in patients with type 1 diabetes mellitus","volume":"8","author":"Moser","year":"2016","journal-title":"Nutrients"},{"key":"B48","doi-asserted-by":"publisher","first-page":"1036","DOI":"10.2337\/dc15-0364","article-title":"Pathway to artificial pancreas systems revisited: moving downstream","volume":"38","author":"Kowalski","year":"2015","journal-title":"Diabetes Care"},{"key":"B49","doi-asserted-by":"publisher","first-page":"532","DOI":"10.1089\/dia.2016.0171","article-title":"Comparison of different treatment modalities for type 1 diabetes, including sensor-augmented insulin regimens, in 52 weeks of follow-up: a COMISAIR study","volume":"18","author":"\u0160oupal","year":"2016","journal-title":"Diabetes Technol Ther"},{"key":"B50","doi-asserted-by":"publisher","first-page":"1473","DOI":"10.1056\/NEJMc1310365","article-title":"Threshold insulin-pump interruption to reduce hypoglycemia","volume":"369","author":"Bergenstal","year":"2013","journal-title":"N Engl J Med"},{"key":"B51","doi-asserted-by":"publisher","first-page":"1795","DOI":"10.1007\/s00125-016-4022-4","article-title":"Coming of age: the artificial pancreas for type 1 diabetes","volume":"59","author":"Thabit","year":"2016","journal-title":"Diabetologia"},{"key":"B52","doi-asserted-by":"publisher","first-page":"k1310","DOI":"10.1136\/bmj.k1310","article-title":"Artificial pancreas treatment for outpatients with type 1 diabetes: systematic review and meta-analysis","volume":"361","author":"Bekiari","year":"2018","journal-title":"BMJ"},{"key":"B53","doi-asserted-by":"publisher","first-page":"501","DOI":"10.1016\/S2213-8587(17)30167-5","article-title":"Effect of artificial pancreas systems on glycaemic control in patients with type 1 diabetes: a systematic review and meta-analysis of outpatient randomised controlled trials","volume":"5","author":"Weisman","year":"2017","journal-title":"Lancet Diabetes Endocrinol"},{"key":"B54","doi-asserted-by":"publisher","first-page":"2157","DOI":"10.1007\/s00125-017-4395-z","article-title":"Closed-loop glucose control in young people with type 1 diabetes during and after unannounced physical activity: a randomised controlled crossover trial","volume":"60","author":"Dovc","year":"2017","journal-title":"Diabetologia"},{"key":"B55","doi-asserted-by":"publisher","first-page":"1644","DOI":"10.2337\/dc17-0883","article-title":"Closed-loop control during intense prolonged outdoor exercise in adolescents with type 1 diabetes: the artificial pancreas Ski study","volume":"40","author":"Breton","year":"2017","journal-title":"Diabetes Care"},{"key":"B56","doi-asserted-by":"publisher","first-page":"794","DOI":"10.1089\/dia.2016.0311","article-title":"Mitigating reductions in glucose during exercise on closed-loop insulin delivery: the ex-snacks study","volume":"18","author":"Patel","year":"2016","journal-title":"Diabetes Technol Ther"},{"key":"B57","doi-asserted-by":"publisher","first-page":"1110","DOI":"10.1111\/dom.12707","article-title":"Randomized trial of a dual-hormone artificial pancreas with dosing adjustment during exercise compared with no adjustment and sensor-augmented pump therapy","volume":"18","author":"Jacobs","year":"2016","journal-title":"Diabetes Obes Metab"},{"key":"B58","doi-asserted-by":"publisher","first-page":"2561","DOI":"10.1007\/s00125-016-4107-0","article-title":"Efficacy of single-hormone and dual-hormone artificial pancreas during continuous and interval exercise in adult patients with type 1 diabetes: randomised controlled crossover trial","volume":"59","author":"Taleb","year":"2016","journal-title":"Diabetologia"},{"key":"B59","doi-asserted-by":"publisher","first-page":"506","DOI":"10.1089\/dia.2013.0333","article-title":"Adding heart rate signal to a control-to-range artificial pancreas system improves the protection against hypoglycemia during exercise in type 1 diabetes","volume":"16","author":"Breton","year":"2014","journal-title":"Diabetes Technol Ther"},{"key":"B60","doi-asserted-by":"publisher","first-page":"1175","DOI":"10.1177\/1932296815609371","article-title":"Incorporating an exercise detection, grading, and hormone dosing algorithm into the artificial pancreas using accelerometry and heart rate","volume":"9","author":"Jacobs","year":"2015","journal-title":"J Diabetes Sci Technol"},{"key":"B61","doi-asserted-by":"publisher","first-page":"1471","DOI":"10.2337\/dc18-0228","article-title":"Randomized outpatient trial of single- and dual-hormone closed-loop systems that adapt to exercise using wearable sensors","volume":"41","author":"Castle","year":"2018","journal-title":"Diabetes Care"},{"key":"B62","doi-asserted-by":"publisher","first-page":"589","DOI":"10.1089\/dia.2017.0204","article-title":"Stability of commercially available glucagon formulation for dual-hormone artificial pancreas clinical use","volume":"19","author":"Taleb","year":"2017","journal-title":"Diabetes Technol Ther"},{"key":"B63","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1111\/dom.12789","article-title":"Glucagon in artificial pancreas systems: potential benefits and safety profile of future chronic use","volume":"19","author":"Taleb","year":"2017","journal-title":"Diabetes Obes Metab"}],"container-title":["Frontiers in Endocrinology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fendo.2018.00818\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,1,18]],"date-time":"2019-01-18T12:41:30Z","timestamp":1547815290000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fendo.2018.00818\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1,18]]},"references-count":63,"alternative-id":["10.3389\/fendo.2018.00818"],"URL":"https:\/\/doi.org\/10.3389\/fendo.2018.00818","relation":{},"ISSN":["1664-2392"],"issn-type":[{"value":"1664-2392","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,1,18]]},"article-number":"818"}}