{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T18:46:53Z","timestamp":1769626013593,"version":"3.49.0"},"reference-count":29,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2019,4,11]],"date-time":"2019-04-11T00:00:00Z","timestamp":1554940800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Endocrinol."],"DOI":"10.3389\/fendo.2019.00234","type":"journal-article","created":{"date-parts":[[2019,4,11]],"date-time":"2019-04-11T13:36:21Z","timestamp":1554989781000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":3,"title":["Plasma Low-Density Lipoprotein Cholesterol Correlates With Heart Function in Individuals With Type 2 Diabetes Mellitus: A Cross-Sectional Study"],"prefix":"10.3389","volume":"10","author":[{"given":"Po-Chung","family":"Cheng","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shang-Ren","family":"Hsu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jung-Chi","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ching-Pei","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Szu-Chi","family":"Chien","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shih-Te","family":"Tu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yun-Chung","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu-Hsiu","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeng-Fu","family":"Kuo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2019,4,11]]},"reference":[{"key":"B1","volume-title":"IDF diabetes atlas.","year":"2017"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/653789","article-title":"Impact of diabetes on cardiovascular disease: an update","author":"Matheus","year":"2013","journal-title":"Int J Hypertens"},{"key":"B3","doi-asserted-by":"publisher","first-page":"171","DOI":"10.3803\/EnM.2017.32.2.171","article-title":"Diabetes-related cardiac dysfunction","volume":"32","author":"Williams","year":"2017","journal-title":"Endocrinol Metab"},{"key":"B4","doi-asserted-by":"publisher","first-page":"1058","DOI":"10.1161\/CIRCRESAHA.110.223545","article-title":"Oxidative stress and diabetic complications","volume":"107","author":"Giacco","year":"2010","journal-title":"Circ Res"},{"key":"B5","doi-asserted-by":"publisher","first-page":"543","DOI":"10.1007\/s10741-010-9168-4","article-title":"Proinflammatory cytokines in heart failure: double-edged swords","volume":"15","author":"Hedayat","year":"2010","journal-title":"Heart Fail Rev"},{"key":"B6","doi-asserted-by":"publisher","first-page":"1377","DOI":"10.2337\/dc12-1550","article-title":"Associations of insulin resistance with cardiovascular risk factors and inflammatory cytokines in normal-weight Hispanic women","volume":"36","author":"Vella","year":"2013","journal-title":"Diabetes Care"},{"key":"B7","doi-asserted-by":"publisher","first-page":"374","DOI":"10.1056\/NEJM199602083340607","article-title":"Hypertension and associated metabolic abnormalities-the role of insulin resistance and the sympathoadrenal system","volume":"334","author":"Reaven","year":"1996","journal-title":"N Engl J Med"},{"key":"B8","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1016\/j.maturitas.2016.03.022","article-title":"Adrenergic signaling in heart failure and cardiovascular aging","volume":"93","author":"Santulli","year":"2016","journal-title":"Maturitas"},{"key":"B9","doi-asserted-by":"publisher","first-page":"516","DOI":"10.3389\/fphys.2016.00516","article-title":"Comparable attenuation of sympathetic nervous system activity in obese subjects with normal glucose tolerance, impaired glucose tolerance, and treatment na\u00efve type 2 diabetes following equivalent weight loss","volume":"7","author":"Straznicky","year":"2016","journal-title":"Front Physiol"},{"key":"B10","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1126\/science.1439783","article-title":"What if Minkowski had been ageusic?","volume":"258","author":"McGarry","year":"1992","journal-title":"Science"},{"key":"B11","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1016\/S0140-6736(63)91500-9","article-title":"The glucose fatty-acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus","volume":"1","author":"Randle","year":"1963","journal-title":"Lancet"},{"key":"B12","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1172\/JCI77812","article-title":"The pathogenesis of insulin resistance: integrating signaling pathways and substrate flux","volume":"126","author":"Samuel","year":"2016","journal-title":"J Clin Invest"},{"key":"B13","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1111\/jch.13453","article-title":"Diabetes, body fat, skeletal muscle, and hypertension: The ominous chiasmus?","volume":"21","author":"Shu","year":"2019","journal-title":"J Clin Hypertens"},{"key":"B14","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.redox.2017.11.017","article-title":"Oxidized LDL triggers changes in oxidative stress and inflammatory biomarkers in human macrophages","volume":"15","author":"Lara-Guzm\u00e1n","year":"2018","journal-title":"Redox Biol"},{"key":"B15","doi-asserted-by":"publisher","first-page":"e13467","DOI":"10.1371\/journal.pone.0013467","article-title":"The relationships of markers of cholesterol homeostasis with carotid intima-media thickness","volume":"5","author":"Weing\u00e4rtner","year":"2010","journal-title":"PLoS ONE"},{"key":"B16","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1536\/ihj.46.619","article-title":"The association between cholesterol and mortality in heart failure: Comparison between patients with and without coronary artery disease","volume":"46","author":"Sakatani","year":"2005","journal-title":"Int Heart J"},{"key":"B17","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.echo.2018.06.004","article-title":"Guidelines for performing a comprehensive transthoracic echocardiographic examination in adults: recommendations from the American Society of Echocardiography","volume":"32","author":"Mitchell","year":"2018","journal-title":"J Am Soc Echocardiogr"},{"key":"B18","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1161\/01.CIR.64.4.744","article-title":"A new, simplified and accurate method for determining ejection fraction with two-dimensional echocardiography","volume":"64","author":"Quinones","year":"1981","journal-title":"Circulation"},{"key":"B19","doi-asserted-by":"publisher","first-page":"2459","DOI":"10.1093\/eurheartj\/ehx144","article-title":"Low-density lipoproteins cause atherosclerotic cardiovascular disease","volume":"38","author":"Ference","year":"2017","journal-title":"Eur Heart J."},{"key":"B20","doi-asserted-by":"publisher","first-page":"353","DOI":"10.1016\/j.hfc.2013.10.002","article-title":"The role of coronary artery disease in heart failure","volume":"10","author":"Lala","year":"2014","journal-title":"Heart Fail Clin"},{"key":"B21","doi-asserted-by":"publisher","first-page":"1555","DOI":"10.1016\/j.bbalip.2016.02.011","article-title":"Lipotoxicity in obesity and diabetes-related cardiac dysfunction","volume":"1861","author":"Zlobine","year":"2016","journal-title":"Biochim Biophys Acta."},{"key":"B22","doi-asserted-by":"publisher","first-page":"R225","DOI":"10.1530\/JME-16-0249","article-title":"Lipid metabolism and its implications for type 1 diabetes-associated cardiomyopathy","volume":"58","author":"Ritchie","year":"2017","journal-title":"J Mol Endocrinol"},{"key":"B23","doi-asserted-by":"publisher","first-page":"e6094","DOI":"10.1097\/MD.0000000000006094","article-title":"Association of total cholesterol and HDL-C levels and outcome in coronary heart disease patients with heart failure","volume":"96","author":"Zhao","year":"2017","journal-title":"Medicine."},{"key":"B24","doi-asserted-by":"publisher","first-page":"336","DOI":"10.1111\/j.1527-5299.2007.07211.x","article-title":"The cholesterol paradox in heart failure","volume":"13","author":"Velavan","year":"2007","journal-title":"Congest Heart Fail"},{"key":"B25","doi-asserted-by":"publisher","first-page":"39033","DOI":"10.1016\/j.jacc.2018.11.002","article-title":"2018 AHA\/ACC\/AACVPR\/AAPA\/ABC\/ACPM\/ADA\/AGS\/APhA\/ASPC\/NLA\/PCNA Guideline on the management of blood cholesterol: a report of the American College of Cardiology\/American Heart Association Task Force on clinical practice guidelines","volume":"18","author":"Grundy","year":"2018","journal-title":"J Am Coll Cardiol"},{"key":"B26","doi-asserted-by":"publisher","first-page":"362","DOI":"10.1007\/s12265-014-9545-9","article-title":"Impact of diabetes mellitus on the clinical response to cardiac resynchronization therapy in elderly people","volume":"7","author":"Sardu","year":"2014","journal-title":"J Cardiovasc Transl Res"},{"key":"B27","doi-asserted-by":"publisher","first-page":"S1","DOI":"10.1186\/2036-7902-5-S1-S1","article-title":"Sources of error in emergency ultrasonography","volume":"5","author":"Pinto","year":"2013","journal-title":"Crit Ultrasound J"},{"key":"B28","doi-asserted-by":"publisher","first-page":"18","DOI":"10.3390\/nu9010018","article-title":"The role of omega-3 polyunsaturated fatty acids in heart failure: a meta-analysis of randomised controlled trials","volume":"9","author":"Wang","year":"2016","journal-title":"Nutrients"},{"key":"B29","doi-asserted-by":"publisher","first-page":"409","DOI":"10.1007\/s10741-018-9703-2","article-title":"SGLT2 inhibition and heart failure-current concepts","volume":"23","author":"Custodio","year":"2018","journal-title":"Heart Fail Rev."}],"container-title":["Frontiers in Endocrinology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fendo.2019.00234\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,11]],"date-time":"2019-04-11T13:36:23Z","timestamp":1554989783000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fendo.2019.00234\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,4,11]]},"references-count":29,"alternative-id":["10.3389\/fendo.2019.00234"],"URL":"https:\/\/doi.org\/10.3389\/fendo.2019.00234","relation":{},"ISSN":["1664-2392"],"issn-type":[{"value":"1664-2392","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,4,11]]},"article-number":"234"}}