{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T05:13:13Z","timestamp":1789621993785,"version":"build-2803163510"},"reference-count":33,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2019,10,23]],"date-time":"2019-10-23T00:00:00Z","timestamp":1571788800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Endocrinol."],"DOI":"10.3389\/fendo.2019.00723","type":"journal-article","created":{"date-parts":[[2019,10,23]],"date-time":"2019-10-23T14:41:08Z","timestamp":1571841668000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":30,"title":["Assisted Reproduction in Congenital Adrenal Hyperplasia"],"prefix":"10.3389","volume":"10","author":[{"given":"Anastasios","family":"Chatziaggelou","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evangelos G.","family":"Sakkas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raffaella","family":"Votino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Papagianni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George","family":"Mastorakos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2019,10,23]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"2194","DOI":"10.1016\/S0140-6736(17)31431-9","article-title":"Congenital adrenal hyperplasia","volume":"390","author":"El-maouche","year":"2017","journal-title":"Lancet"},{"key":"B2","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1016\/j.ecl.2015.02.002","article-title":"Adrenal steroidogenesis and congenital adrenal hyperplasia","volume":"44","author":"Turcu","year":"2015","journal-title":"Endocrinol Metab Clin North Am"},{"key":"B3","doi-asserted-by":"publisher","first-page":"178","DOI":"10.1007\/s12098-013-1280-8","article-title":"Congenital adrenal hyperplasia : issues in diagnosis and treatment in children","volume":"81","author":"Sharma","year":"2014","journal-title":"Indian J Pediatr"},{"key":"B4","doi-asserted-by":"publisher","first-page":"267","DOI":"10.1016\/j.ecl.2016.01.001","article-title":"Prenatal diagnosis of congenital adrenal hyperplasia","volume":"45","author":"Yau","year":"2016","journal-title":"Endocrinol Metab Clin North Am"},{"key":"B5","doi-asserted-by":"publisher","first-page":"520","DOI":"10.1016\/j.jpag.2017.04.001","article-title":"Congenital adrenal hyperplasia","volume":"30","author":"Witchel","year":"2017","journal-title":"J Pediatr Adolesc Gynecol"},{"key":"B6","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1038\/nrendo.2013.239","article-title":"Treatment and health outcomes in adults with congenital adrenal hyperplasia","volume":"10","author":"Han","year":"2014","journal-title":"Nat Rev Endocrinol"},{"key":"B7","doi-asserted-by":"publisher","first-page":"144","DOI":"10.1590\/0004-2730000003021","article-title":"Female infertility of endocrine origin","volume":"58","author":"Weiss","year":"2014","journal-title":"Arq Bras Endocrinol Metabol"},{"key":"B8","doi-asserted-by":"publisher","first-page":"705","DOI":"10.1016\/j.ecl.2015.07.009","article-title":"Infertility and reproductive function in patients with congenital adrenal hyperplasia: pathophysiology, advances in management, and recent outcomes","volume":"44","author":"Lekarev","year":"2015","journal-title":"Endocrinol Metab Clin North Am"},{"key":"B9","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1007\/s12020-015-0656-0","article-title":"Nonclassic congenital adrenal hyperplasia due to 21-hydroxylase deficiency: clinical presentation, diagnosis, treatment, and outcome","volume":"50","author":"Falhammar","year":"2015","journal-title":"Endocrine"},{"key":"B10","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1530\/EJE-16-0888","article-title":"Congenital adrenal hyperplasia due to 21-hydroxylase deficiency: update in management of adult patients and prenatal treatment","volume":"4","author":"Bachelot","year":"2017","journal-title":"Eur J Endocrinol"},{"key":"B11","doi-asserted-by":"publisher","first-page":"14","DOI":"10.4103\/2230-8210.119491","article-title":"Congenital adrenal hyperplasia: treatment and outcomes","volume":"17","author":"Kamoun","year":"2013","journal-title":"Indian J Endocrinol Metab"},{"key":"B12","doi-asserted-by":"publisher","first-page":"21","DOI":"10.12688\/f1000research.6543.1","article-title":"Congenital adrenal hyperplasia [version 1; peer review: 2 approved]","volume":"4","author":"Speiser","year":"2015","journal-title":"F1000Res"},{"key":"B13","doi-asserted-by":"publisher","first-page":"833","DOI":"10.1111\/j.1365-2265.2009.03563.x","article-title":"Reassessing fecundity in women with classical congenital adrenal hyperplasia (CAH): normal pregnancy rate but reduced fertility rate","volume":"70","author":"Casteras","year":"2009","journal-title":"Clin Endocrinol"},{"key":"B14","doi-asserted-by":"publisher","first-page":"184","DOI":"10.1159\/000443919","article-title":"Congenital adrenal hyperplasia: unresolved issues","volume":"46","author":"Yau","year":"2016","journal-title":"Front Horm Res"},{"key":"B15","doi-asserted-by":"publisher","first-page":"5110","DOI":"10.1210\/jc.2010-0917","article-title":"Health status of adults with congenital adrenal hyperplasia : a cohort study of 203 patients","volume":"95","author":"Arlt","year":"2010","journal-title":"J Clin Endocrinol Metab"},{"key":"B16","doi-asserted-by":"publisher","first-page":"1182","DOI":"10.1210\/jc.2009-1383","article-title":"Fertility in women with nonclassical congenital adrenal hyperplasia due to 21-hydroxylase","volume":"95","author":"Bidet","year":"2010","journal-title":"J Clin Endocrinol Metab"},{"key":"B17","doi-asserted-by":"publisher","first-page":"635","DOI":"10.1210\/jcem.74.3.1310999","article-title":"Fertility in women with late-onset adrenal hyperplasia due to 21-hydroxylase deficiency","volume":"74","author":"Feldman","year":"1992","journal-title":"J Clin Endocrinol Metab"},{"key":"B18","doi-asserted-by":"publisher","first-page":"3451","DOI":"10.1210\/jc.2006-0062","article-title":"Reproductive outcome of women with 21-hydroxylase- deficient nonclassic adrenal hyperplasia","volume":"91","author":"Moran","year":"2006","journal-title":"J Clin Endocrinol Metab"},{"key":"B19","doi-asserted-by":"publisher","first-page":"311","DOI":"10.2165\/00148581-200608050-00004","article-title":"Polycystic ovary syndrome in adolescents: current and future treatment options","volume":"8","author":"Mastorakos","year":"2006","journal-title":"Pediatr Drugs"},{"key":"B20","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1016\/j.fertnstert.2013.11.002","article-title":"Fertility in patients with congenital adrenal hyperplasia","volume":"101","author":"Reichman","year":"2014","journal-title":"Fertil Steril"},{"key":"B21","doi-asserted-by":"publisher","first-page":"190","DOI":"10.1016\/j.mce.2015.01.039","article-title":"Management considerations for the adullt with congenitaladrenal hyperplasia","volume":"408","author":"Auchus","year":"2015","journal-title":"Mol Cell Endocrinol"},{"key":"B22","doi-asserted-by":"publisher","first-page":"296","DOI":"10.1016\/j.jpag.2012.08.004","article-title":"Research on quality of life in female patients with congenital adrenal hyperplasia and issues in developing nations","volume":"26","author":"Zainuddin","year":"2013","journal-title":"J Pediatr Adolesc Gynecol"},{"key":"B23","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1016\/j.jsbmb.2016.06.015","article-title":"Steroid 21-hydroxylase deficiency in congenital adrenal hyperplasia","volume":"165","author":"Parsa","year":"2017","journal-title":"J Steroid Biochem Mol Biol"},{"key":"B24","doi-asserted-by":"publisher","first-page":"341","DOI":"10.1016\/S2213-8587(13)70138-4","article-title":"Management of adolescents with congenital adrenal hyperplasia","volume":"1","author":"Merke","year":"2013","journal-title":"Lancet Diabetes Endocrinol"},{"key":"B25","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1097\/MED.0000000000000256","article-title":"Novel treatment strategies in congenital adrenal hyperplasia","volume":"23","author":"Turcu","year":"2016","journal-title":"Curr Opin Endocrinol Diabetes Obes"},{"key":"B26","doi-asserted-by":"publisher","first-page":"2645","DOI":"10.1210\/jc.2013-1440","article-title":"Approach to the patient: the adult with congenital adrenal hyperplasia","volume":"98","author":"Auchus","year":"2013","journal-title":"J Clin Endocrinol Metab"},{"key":"B27","doi-asserted-by":"publisher","first-page":"4043","DOI":"10.1210\/jc.2018-01865","article-title":"Congenital adrenal hyperplasia due to steroid 21-hydroxylase deficiency : an endocrine society * clinical practice guideline","volume":"103","author":"Speiser","year":"2018","journal-title":"J Clin Endocrinol Metab"},{"key":"B28","doi-asserted-by":"publisher","first-page":"25","DOI":"10.18388\/abp.2017_2343","article-title":"Congenital adrenal hyperplasia : clinical symptoms and diagnostic methods","volume":"65","author":"Podg\u00f3rski","year":"2018","journal-title":"ACTA Biochim Pol"},{"key":"B29","doi-asserted-by":"publisher","first-page":"15691","DOI":"10.1038\/s41598-018-34075-6","article-title":"Biochemistry, hormones and adipocytokines in prepubertal children born with IUGR evoke metabolic, hepatic and renal derangements","volume":"1","author":"Sidiropoulou","year":"2018","journal-title":"Sci Rep"},{"key":"B30","doi-asserted-by":"publisher","first-page":"2609","DOI":"10.1093\/humrep\/dew239","article-title":"Successful IVF pregnancy despite inadequate ovarian steroidogenesis due to congenital lipoid adrenal hyperplasia (CLAH): a case report","volume":"31","author":"Albarel","year":"2016","journal-title":"Hum Reprod"},{"key":"B31","doi-asserted-by":"publisher","first-page":"345","DOI":"10.1210\/jc.2015-3201","article-title":"Successful live birth in a woman with 17\u03b1 - hydroxylase deficiency through IVF frozen-thawed embryo transfer","volume":"101","author":"Bianchi","year":"2016","journal-title":"J Clin Endocrinol Metab"},{"key":"B32","doi-asserted-by":"publisher","first-page":"400","DOI":"10.1055\/s-0029-1211475","article-title":"Substitution with testosterone as aromatizable substrate for induction of follicular maturation, estradiol production and ovulation in a patient with 17a-hydroxylase deficiency","volume":"104","author":"Neuwinger","year":"1996","journal-title":"Exp Clin Endocrinol Diabetes"},{"key":"B33","doi-asserted-by":"publisher","first-page":"2456","DOI":"10.1093\/oxfordjournals.humrep.a136319","article-title":"Induction of artificial endometrial cycles with oestradiol implants and injectable progesterone: establishment of a viable pregnancy in a woman with 17-\u03b1-hydroxylase deficiency","volume":"10","author":"Ben-Nun","year":"1995","journal-title":"Hum Reprod"}],"container-title":["Frontiers in Endocrinology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fendo.2019.00723\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,10,24]],"date-time":"2019-10-24T15:07:13Z","timestamp":1571929633000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fendo.2019.00723\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,10,23]]},"references-count":33,"alternative-id":["10.3389\/fendo.2019.00723"],"URL":"https:\/\/doi.org\/10.3389\/fendo.2019.00723","relation":{},"ISSN":["1664-2392"],"issn-type":[{"value":"1664-2392","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,10,23]]},"article-number":"723"}}