{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T13:46:58Z","timestamp":1789480018210,"version":"build-2803163510"},"reference-count":39,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2020,2,20]],"date-time":"2020-02-20T00:00:00Z","timestamp":1582156800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003399","name":"Science and Technology Commission of Shanghai Municipality","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003399","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Endocrinol."],"DOI":"10.3389\/fendo.2020.00055","type":"journal-article","created":{"date-parts":[[2020,2,19]],"date-time":"2020-02-19T23:53:17Z","timestamp":1582156397000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":46,"title":["The Associations Between Gonadal Hormones and Serum Uric Acid Levels in Men and Postmenopausal Women With Diabetes"],"prefix":"10.3389","volume":"11","author":[{"given":"Heng","family":"Wan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kun","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuying","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fangzhen","family":"Xia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunping","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ningjian","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yingli","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2020,2,20]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"1066","DOI":"10.1080\/14397595.2017.1300117","article-title":"Prevalence and risk factors of hyperuricemia: results of the kailuan cohort study","volume":"27","author":"Cui","year":"2017","journal-title":"Mod Rheumatol"},{"key":"B2","doi-asserted-by":"publisher","first-page":"513","DOI":"10.1016\/j.jare.2017.04.005","article-title":"Epidemiology, pathophysiology, and management of uric acid urolithiasis: a narrative review","volume":"8","author":"Abou-Elela","year":"2017","journal-title":"J Adv Res"},{"key":"B3","doi-asserted-by":"publisher","first-page":"1811","DOI":"10.1056\/NEJMra0800885","article-title":"Uric acid and cardiovascular risk","volume":"359","author":"Feig","year":"2008","journal-title":"N Engl J Med"},{"key":"B4","doi-asserted-by":"publisher","first-page":"1737","DOI":"10.2337\/dc09-0288","article-title":"Association between serum uric acid and development of type 2 diabetes","volume":"32","author":"Kodama","year":"2009","journal-title":"Diabetes Care"},{"key":"B5","doi-asserted-by":"publisher","first-page":"420","DOI":"10.1177\/0003319711423806","article-title":"Serum uric acid: a marker of metabolic syndrome and subclinical atherosclerosis in Korean men","volume":"63","author":"Zhang","year":"2012","journal-title":"Angiology"},{"key":"B6","doi-asserted-by":"publisher","first-page":"S3","DOI":"10.1097\/HJH.0000000000001330","article-title":"Association between serum uric acid and cardiovascular mortality and all-cause mortality: a cohort study","volume":"35","author":"Cheong","year":"2017","journal-title":"J Hypertens"},{"key":"B7","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1016\/j.atherosclerosis.2017.03.008","article-title":"On the non-linear association between serum uric acid levels and all-cause mortality rate in patients with type 2 diabetes mellitus","volume":"260","author":"Lamacchia","year":"2017","journal-title":"Atherosclerosis"},{"key":"B8","doi-asserted-by":"publisher","first-page":"325","DOI":"10.1002\/dmrr.2724","article-title":"Association between uric acid, cancer incidence and mortality in patients with type 2 diabetes: Shanghai diabetes registry study","volume":"32","author":"Deng","year":"2016","journal-title":"Diabetes Metab Res Rev"},{"key":"B9","doi-asserted-by":"publisher","first-page":"428","DOI":"10.1111\/1753-0407.12517","article-title":"Sex differences, endogenous sex-hormone hormones, sex-hormone binding globulin, and exogenous disruptors in diabetes and related metabolic outcomes","volume":"10","author":"Liu","year":"2018","journal-title":"J Diabetes"},{"key":"B10","doi-asserted-by":"publisher","first-page":"4314","DOI":"10.1038\/s41598-018-22570-9","article-title":"Prevalence and correlates of hyperuricemia in the middle-aged and older adults in china","volume":"8","author":"Song","year":"2018","journal-title":"Sci Rep"},{"key":"B11","doi-asserted-by":"publisher","first-page":"2087","DOI":"10.1038\/s41598-017-02392-x","article-title":"Serum uric acid is associated with erectile dysfunction: a population-based cross-sectional study in Chinese men","volume":"7","author":"Gao","year":"2017","journal-title":"Sci Rep"},{"key":"B12","doi-asserted-by":"publisher","first-page":"e0162004","DOI":"10.1371\/journal.pone.0162004","article-title":"Low sex hormone-binding globulin levels associate with prediabetes in Chinese men independent of total testosterone","volume":"11","author":"Zhu","year":"2016","journal-title":"PLoS ONE"},{"key":"B13","doi-asserted-by":"publisher","first-page":"4375253","DOI":"10.1155\/2017\/4375253","article-title":"Association between sex hormone and blood uric acid in male patients with type 2 diabetes","volume":"2017","author":"Cao","year":"2017","journal-title":"Int J Endocrinol"},{"key":"B14","first-page":"155","article-title":"Obesity and metabolic complications: contribution of dehydroepiandrosterone and other steroid hormones","volume":"150","author":"Tchernof","year":"1996","journal-title":"J Endocrinol"},{"key":"B15","doi-asserted-by":"publisher","first-page":"2893","DOI":"10.2337\/diacare.27.12.2893","article-title":"Association between urinary albumin excretion and serum dehydroepiandrosterone sulfate concentration in male patients with type 2 diabetes: a possible link between urinary albumin excretion and cardiovascular disease","volume":"27","author":"Fukui","year":"2004","journal-title":"Diabetes Care"},{"key":"B16","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1186\/s12933-019-0901-6","article-title":"Novel associations between sex hormones and diabetic vascular complications in men and postmenopausal women: a cross-sectional study","volume":"18","author":"Wang","year":"2019","journal-title":"Cardiovasc Diabetol"},{"key":"B17","doi-asserted-by":"publisher","first-page":"4708","DOI":"10.1210\/jc.2003-031560","article-title":"Dehydroepiandrosterone increases endothelial cell proliferation in vitro and improves endothelial function in vivo by mechanisms independent of androgen and estrogen receptors","volume":"89","author":"Williams","year":"2004","journal-title":"J Clin Endocrinol Metab"},{"key":"B18","doi-asserted-by":"publisher","first-page":"1159","DOI":"10.1210\/jc.2011-3362","article-title":"Executive summary of the stages of reproductive aging workshop + 10: addressing the unfinished agenda of staging reproductive aging","volume":"97","author":"Harlow","year":"2012","journal-title":"J Clin Endocrinol Metab"},{"key":"B19","doi-asserted-by":"publisher","first-page":"809","DOI":"10.4158\/EP-2019-0015","article-title":"Associations between vitamin d and microvascular complications in middle-aged and elderly diabetic patients","volume":"25","author":"Wan","year":"2019","journal-title":"Endocr Pract."},{"key":"B20","doi-asserted-by":"publisher","first-page":"30064","DOI":"10.1016\/j.diabet.2019.04.004","article-title":"Association of c-peptide with diabetic vascular complications in type 2 diabetes","volume":"3636","author":"Wang","year":"2019","journal-title":"Diabetes Metab."},{"key":"B21","doi-asserted-by":"publisher","first-page":"2218","DOI":"10.1210\/jc.2016-1076","article-title":"Exposure to famine in early life and nonalcoholic fatty liver disease in adulthood","volume":"101","author":"Wang","year":"2016","journal-title":"J Clin Endocrinol Metab"},{"key":"B22","doi-asserted-by":"publisher","first-page":"948","DOI":"10.1001\/jama.2013.168118","article-title":"Prevalence and control of diabetes in Chinese adults","volume":"310","author":"Xu","year":"2013","journal-title":"JAMA"},{"key":"B23","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1111\/j.1753-0407.2009.00062.x","article-title":"Prehypertension is associated with atherosclerosis in type 2 diabetes","volume":"2","author":"Tan","year":"2010","journal-title":"J Diabetes"},{"key":"B24","doi-asserted-by":"publisher","first-page":"6039","DOI":"10.1210\/jc.2004-0735","article-title":"Endogenous sex hormones in relation to age, sex, lifestyle factors, and chronic diseases in a general population: the tromso study","volume":"89","author":"Bjornerem","year":"2004","journal-title":"J Clin Endocrinol Metab"},{"key":"B25","doi-asserted-by":"publisher","first-page":"561","DOI":"10.1038\/nrrheum.2017.126","article-title":"Discordant american college of physicians and international rheumatology guidelines for gout management: consensus statement of the gout, hyperuricemia and crystal-associated disease network (g-can)","volume":"13","author":"Dalbeth","year":"2017","journal-title":"Nat Rev Rheumatol"},{"key":"B26","doi-asserted-by":"publisher","first-page":"352","DOI":"10.2337\/dci18-0051","article-title":"2018 Health care & education presidential address: the american diabetes association in the era of health care transformation","volume":"42","author":"Hill-Briggs","year":"2019","journal-title":"Diabetes Care"},{"key":"B27","doi-asserted-by":"publisher","first-page":"555","DOI":"10.1038\/ki.2010.462","article-title":"Evaluation of the chronic kidney disease epidemiology collaboration equation for estimating the glomerular filtration rate in multiple ethnicities","volume":"79","author":"Stevens","year":"2011","journal-title":"Kidney Int"},{"key":"B28","doi-asserted-by":"publisher","first-page":"551","DOI":"10.1210\/jcem-59-3-551","article-title":"Age changes and sex differences in serum dehydroepiandrosterone sulfate concentrations throughout adulthood","volume":"59","author":"Orentreich","year":"1984","journal-title":"J Clin Endocrinol Metab"},{"key":"B29","doi-asserted-by":"publisher","first-page":"355","DOI":"10.1016\/bs.vh.2018.01.008","article-title":"Effect of dehydroepiandrosterone (dhea) on diabetes mellitus and obesity","volume":"108","author":"Aoki","year":"2018","journal-title":"Vitam Horm"},{"key":"B30","doi-asserted-by":"publisher","first-page":"98","DOI":"10.1007\/s00125-016-4136-8","article-title":"Serum dehydroepiandrosterone levels are associated with lower risk of type 2 diabetes: the rotterdam study","volume":"60","author":"Brahimaj","year":"2017","journal-title":"Diabetologia"},{"key":"B31","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1016\/bs.vh.2018.02.003","article-title":"Mechanisms of action of dehydroepiandrosterone","volume":"108","author":"Clark","year":"2018","journal-title":"Vitam Horm"},{"key":"B32","doi-asserted-by":"publisher","first-page":"198","DOI":"10.1530\/acta.0.0850198","article-title":"The relationship of sex steroids to uric acid levels in plasma and urine","volume":"85","author":"Adamopoulos","year":"1977","journal-title":"Acta Endocrinol"},{"key":"B33","doi-asserted-by":"publisher","first-page":"1321","DOI":"10.1507\/endocrj.EJ13-0203","article-title":"Testosterone replacement elevates the serum uric acid levels in patients with female to male gender identity disorder","volume":"60","author":"Kurahashi","year":"2013","journal-title":"Endocr J"},{"key":"B34","doi-asserted-by":"publisher","first-page":"2230","DOI":"10.1210\/jc.2007-2467","article-title":"Effect of long-term administration of cross-sex hormone therapy on serum and urinary uric acid in transsexual persons","volume":"93","author":"Yahyaoui","year":"2008","journal-title":"J Clin Endocrinol Metab"},{"key":"B35","doi-asserted-by":"publisher","first-page":"1853","DOI":"10.1093\/humrep\/det085","article-title":"Serum uric acid in relation to endogenous reproductive hormones during the menstrual cycle: findings from the biocycle study","volume":"28","author":"Mumford","year":"2013","journal-title":"Hum Reprod"},{"key":"B36","doi-asserted-by":"publisher","first-page":"1211","DOI":"10.1097\/GME.0000000000000230","article-title":"Aging, not menopause, is associated with higher prevalence of hyperuricemia among older women","volume":"21","author":"Krishnan","year":"2014","journal-title":"Menopause"},{"key":"B37","doi-asserted-by":"publisher","first-page":"650","DOI":"10.1016\/S0140-6736(99)92381-4","article-title":"Reduction of serum uric acid by hormone replacement therapy in postmenopausal women with hyperuricaemia","volume":"354","author":"Sumino","year":"1999","journal-title":"Lancet"},{"key":"B38","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1097\/GME.0000000000000953","article-title":"Serum uric acid levels and hormone therapy type: a retrospective cohort study of postmenopausal women","volume":"25","author":"Jung","year":"2018","journal-title":"Menopause"},{"key":"B39","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1002\/art.1780280203","article-title":"Plasma follicle-stimulating hormone, luteinizing hormone, and sex hormones in patients with gout","volume":"28","author":"Marinello","year":"1985","journal-title":"Arthritis Rheum"}],"container-title":["Frontiers in Endocrinology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fendo.2020.00055\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,2,19]],"date-time":"2020-02-19T23:53:20Z","timestamp":1582156400000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fendo.2020.00055\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,2,20]]},"references-count":39,"alternative-id":["10.3389\/fendo.2020.00055"],"URL":"https:\/\/doi.org\/10.3389\/fendo.2020.00055","relation":{},"ISSN":["1664-2392"],"issn-type":[{"value":"1664-2392","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,2,20]]},"article-number":"55"}}