{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T10:41:31Z","timestamp":1784889691049,"version":"3.55.0"},"reference-count":59,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2021,8,10]],"date-time":"2021-08-10T00:00:00Z","timestamp":1628553600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Endocrinol."],"abstract":"<jats:p>Congenital hypothyroidism (CH) is an endocrine disease commonly found in newborns and is related to the absence or reduction of thyroid hormones (THs), which are essential for development since intrauterine life. Children with CH can develop hearing problems as THs are crucial for the auditory pathway\u2019s development and maturation. Sensory deprivations, especially in hearing disorders at early ages of development, can impair language skills, literacy, and behavioral, cognitive, social, and psychosocial development. In this review we describe clinical and molecular aspects linking CH and hearing loss.<\/jats:p>","DOI":"10.3389\/fendo.2021.671784","type":"journal-article","created":{"date-parts":[[2021,8,10]],"date-time":"2021-08-10T05:16:59Z","timestamp":1628572619000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":11,"title":["Congenital Hypothyroidism and the Deleterious Effects on Auditory Function and Language Skills: A Narrative Review"],"prefix":"10.3389","volume":"12","author":[{"given":"Caio Le\u00f4nidas Oliveira","family":"Andrade","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cr\u00e9sio de Arag\u00e3o Dantas","family":"Alves","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helton Estrela","family":"Ramos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2021,8,10]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1159\/000259194","article-title":"The Importance of Thyroid Hormone for Auditory Development in the Fetus and Neonate","volume":"1","author":"Sohmer","year":"1996","journal-title":"Audiol Neurootol"},{"key":"B2","doi-asserted-by":"publisher","first-page":"296","DOI":"10.1038\/nrendo.2013.58","article-title":"Making Sense With Thyroid Hormone\u2013the Role of T3 in Auditory Development","volume":"9","author":"Ng","year":"2013","journal-title":"Nat Rev Endocrinol"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1590\/2359-3997000000292","article-title":"Mechanisms Involved in Hearing Disorders of Thyroid Ontogeny: A Literature Review","volume":"61","author":"de Andrade","year":"2017","journal-title":"Arch Endocrinol Metab"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1016\/0165-3806(85)90237-8","article-title":"Corrective Effects of Thyroxine on Cochlear Abnormalities Induced by Congenital Hypothyroidism in the Rat. 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