{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T07:51:39Z","timestamp":1793692299692,"version":"4.5.1"},"reference-count":103,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2021,7,16]],"date-time":"2021-07-16T00:00:00Z","timestamp":1626393600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Endocrinol."],"abstract":"<jats:p>Hydrogen sulfide (H<jats:sub>2<\/jats:sub>S), as one of the three known gaseous signal transduction molecules in organisms, has attracted a surging amount of attention. H<jats:sub>2<\/jats:sub>S is involved in a variety of physiological and pathological processes in the body, such as dilating blood vessels (regulating blood pressure), protecting tissue from ischemia-reperfusion injury, anti-inflammation, carcinogenesis, or inhibition of cancer, as well as acting on the hypothalamus and pancreas to regulate hormonal metabolism. The change of H<jats:sub>2<\/jats:sub>S concentration is related to a variety of endocrine disorders, and the change of hormone concentration also affects the synthesis of H<jats:sub>2<\/jats:sub>S. Understanding the effect of biosynthesis and the concentration of H<jats:sub>2<\/jats:sub>S on the endocrine system is useful to develop drugs for the treatment of hypertension, diabetes, and other diseases.<\/jats:p>","DOI":"10.3389\/fendo.2021.704620","type":"journal-article","created":{"date-parts":[[2021,7,16]],"date-time":"2021-07-16T11:39:30Z","timestamp":1626435570000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":24,"title":["Role of Hydrogen Sulfide in the Endocrine System"],"prefix":"10.3389","volume":"12","author":[{"given":"Hao-Jie","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ebenezeri Erasto","family":"Ngowi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Qian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tao","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang-Zhe","family":"Qin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing-Jing","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ke","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin-Ying","family":"Ji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong-Dong","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2021,7,16]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-2952(89)90288-8","article-title":"Acute Hydrogen Sulfide Poisoning. 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