{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T16:14:05Z","timestamp":1792512845857,"version":"4.5.0"},"reference-count":36,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2021,9,27]],"date-time":"2021-09-27T00:00:00Z","timestamp":1632700800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Endocrinol."],"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To analyze the correlation between ovarian reserve and thyroid function in women with infertility.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Retrospective analysis of the data of 496 infertility patients who visited the clinic between January 2019 and December 2020. According to the TSH level, it is grouped into &amp;lt;2.5 mIU\/L, 2.5~4.0mIU\/L and \u22654.0 mIU\/L or according to the positive\/negative thyroid autoimmune antibody. The relationship was assessed through the ovarian reserve, thyroid function, and anti-M\u00fcllerian hormone (AMH) levels in infertile patients. On the other hand, the patients are divided into groups according to age (\u226429 years old, 30-34 years old and \u226535 years old), basic FSH (&amp;lt;10 IU\/L and \u226510 IU\/L), and AMH levels. The ovarian reserve was evaluated through the AMH and the antral follicle count (AFC).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The average age of the patients was 30.31 \u00b1 4.50 years old, and the average AMH level was 5.13 \u00b1 4.30 ng\/mL. 3.63% (18\/496) of patients had abnormal TSH levels (normal: 0.35-5.5 mIU\/L), the positive rate of thyroid peroxidase antibody (TPOAb) was 14.52% (72\/496), the positive rate of anti-thyroglobulin antibody (TgAb) was 16.94% (84\/496), and the positive rate of TPOAb and TgAb was 10.48% (52\/496). After grouping according to TSH level or thyroid autoimmune antibody positive\/negative grouping, the analysis found that there was no statistical significance in age, AMH level and basic FSH level among the groups (P&amp;gt;0.05). There were no significant differences in the levels of TSH, FT3, and FT4 among different ages, AMH, and FSH levels (P&amp;gt;0.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>There is no significant correlation between ovarian reserve and thyroid function in infertile women.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fendo.2021.745199","type":"journal-article","created":{"date-parts":[[2021,9,27]],"date-time":"2021-09-27T16:48:45Z","timestamp":1632761325000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":16,"title":["Correlation Analysis Between Ovarian Reserve and Thyroid Hormone Levels in Infertile Women of Reproductive Age"],"prefix":"10.3389","volume":"12","author":[{"given":"Jie","family":"Wu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying-jie","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming-qiang","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yao-fang","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2021,9,27]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.5653\/cerm.2015.42.4.131","article-title":"Thyroid Dysfunction and Subfertility","volume":"42","author":"Cho","year":"2015","journal-title":"Clin Exp Reprod Med"},{"key":"B2","doi-asserted-by":"publisher","first-page":"799","DOI":"10.1111\/cen.12824","article-title":"Management of Primary Hypothyroidism: Statement by the British Thyroid Association Executive Committee","volume":"84","author":"Okosieme","year":"2016","journal-title":"Clin Endocrinol (Oxf)"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2014.0028","article-title":"American Thyroid Association Task Force on Thyroid Hormone Replacement. 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