{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T11:21:19Z","timestamp":1787311279694,"version":"build-2736575974"},"reference-count":30,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2022,1,4]],"date-time":"2022-01-04T00:00:00Z","timestamp":1641254400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Endocrinol."],"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Postoperative neck symptoms, including pain, swelling, uncomfortable feelings during swallowing, and incision adhesion formation, are common in patients after lobectomy through the traditional middle neck approach. A new unilateral supraclavicular approach is proposed to protect the anterior cervical region and reduce related complications. The aim of this study is to investigate the efficacy, safety, and advantages of the supraclavicular approach in lobectomy for unilateral papillary thyroid microcarcinoma (PTMC).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Two hundred sixty-three patients were recruited into either a conventional middle group (CM) or a new supraclavicular (NS) group. Clinicopathological features, surgically related variables, and postoperative symptoms were recorded. Quality of life (QOL) of all patients was assessed by the 12-item short-form health survey (SF-12) and thyroid cancer-specific QOL (THYCA-QoL) questionnaire in 3 and 12 months.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      There were no statistically significant differences in clinicopathological features (including sex, age, multifocality, extrathyroidal extension, histological variants, largest tumor diameter, Hashimoto\u2019s thyroiditis, metastasized central lymph node, removed central lymph node, surgeon, BRAF mutation, and follow-up duration), hospitalization (including hospital cost, surgery time, and blood loss during surgery), and complications between the two groups. Patients who underwent lobectomy through the NS approach had significantly better SF-12 physical, mental, and THYCA-QoL than the CM group patients in both 3 and 12 months (all\n                      <jats:italic>p<\/jats:italic>\n                      &amp;lt; 0.001). Moreover, the NS group had a shorter hospitalization time.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In conclusion, the NS approach for lobectomy is a safe and effective method for reducing postoperative symptoms and increasing QOL in patients with unilateral PTMC in both 3 and 12 months\u2019 follow-up.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fendo.2021.766444","type":"journal-article","created":{"date-parts":[[2022,1,4]],"date-time":"2022-01-04T02:25:29Z","timestamp":1641263129000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":9,"title":["Supraclavicular Approach of Lobectomy Improves Quality of Life for Patients With Unilateral Papillary Thyroid Microcarcinoma: A Prospective Cohort Study"],"prefix":"10.3389","volume":"12","author":[{"given":"Shuai","family":"Xue","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiuli","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guang","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peisong","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2022,1,4]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"7","DOI":"10.3322\/caac.21387","article-title":"Cancer Statistics, 2017","volume":"67","author":"Siegel","year":"2017","journal-title":"CA Cancer J Clin"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1038\/nrendo.2016.110","article-title":"The Changing Incidence of Thyroid Cancer","volume":"12","author":"Kitahara","year":"2016","journal-title":"Nat Rev Endocrinol"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1177\/1066896913517394","article-title":"Papillary Thyroid Microcarcinoma:How to Diagnose and Manage This Epidemic","volume":"22","author":"Soares","year":"2014","journal-title":"Int J Surg Pathol"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1155\/2021\/5544232","article-title":"The Overdiagnosis of Thyroid Micropapillary Carcinoma: The Rising Incidence, Inert Biological Behavior, and Countermeasures","volume":"2021","author":"Xu","year":"2021","journal-title":"J Oncol"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2017.2719","article-title":"Trends in Thyroid Cancer Incidence and Mortality in the United States, 1974-2013","volume":"317","author":"Lim","year":"2017","journal-title":"JAMA"},{"key":"B6","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1089\/thy.2015.0020","article-title":"2015 American Thyroid Association Management Guidelines for Adult Patients With Thyroid Nodules and Differentiated Thyroid Cancer: The American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer","volume":"26","author":"Haugen","year":"2016","journal-title":"Thyroid"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2016.0483","article-title":"Clinicians' Views on Management and Terminology for Papillary Thyroid Microcarcinoma: A Qualitative Study","volume":"27","author":"Nickel","year":"2017","journal-title":"Thyroid"},{"key":"B8","doi-asserted-by":"publisher","first-page":"471","DOI":"10.1186\/s12885-021-08230-8","article-title":"Active Surveillance for Thyroid Cancer: A Qualitative Study of Barriers and Facilitators to Implementation","volume":"21","author":"Jensen","year":"2021","journal-title":"BMC Cancer"},{"key":"B9","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.eprac.2020.11.003","article-title":"National Survey of Endocrinologists and Surgeons Regarding Active Surveillance for Low-Risk Papillary Thyroid Cancer","volume":"27","author":"Roman","year":"2021","journal-title":"Endocr Pract"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.15386\/cjmed-703","article-title":"Quality of Life in Thyroid Cancer Patients: A Literature Review","volume":"90","author":"Barbus","year":"2017","journal-title":"Clujul Med"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2018.05.029","article-title":"Effect of Wound Massage on Neck Discomfort and Voice Changes After Thyroidectomy","volume":"164","author":"Lee","year":"2018","journal-title":"Surgery"},{"key":"B12","doi-asserted-by":"publisher","first-page":"S94","DOI":"10.1016\/j.ijsu.2017.03.078","article-title":"Swallowing Disorders After Thyroidectomy: What We Know and Where We Are. 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