{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T10:28:52Z","timestamp":1760956132181,"version":"3.41.2"},"reference-count":10,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2021,11,17]],"date-time":"2021-11-17T00:00:00Z","timestamp":1637107200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Endocrinol."],"DOI":"10.3389\/fendo.2021.797228","type":"journal-article","created":{"date-parts":[[2021,11,17]],"date-time":"2021-11-17T07:05:32Z","timestamp":1637132732000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":2,"title":["Editorial: Male Idiopathic Infertility: Novel Possible Targets, Volume I"],"prefix":"10.3389","volume":"12","author":[{"given":"Rossella","family":"Cannarella","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rosita A.","family":"Condorelli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Davor","family":"Jezek","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aldo E.","family":"Calogero","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2021,11,17]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dmx022","article-title":"Temporal Trends in Sperm Count: A Systematic Review and Meta-Regression Analysis","volume":"23","author":"Levine","year":"2017","journal-title":"Hum Reprod Update"},{"key":"B2","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1186\/s12958-015-0032-1","article-title":"A Unique View on Male Infertility Around the Globe","volume":"13","author":"Agarwal","year":"2015","journal-title":"Reprod Biol Endocrinol"},{"key":"B3","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1038\/nrurol.2012.234","article-title":"Follicle-Stimulating Hormone Treatment in Normogonadotropic Infertile Men","volume":"10","author":"Valenti","year":"2013","journal-title":"Nat Rev Urol"},{"key":"B4","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1093\/humrep\/dew284","article-title":"Causes of Male Infertility: A 9-Year Prospective Monocentre Study on 1737 Patients With Reduced Total Sperm Counts","volume":"32","author":"Punab","year":"2017","journal-title":"Hum Reprod"},{"key":"B5","doi-asserted-by":"publisher","first-page":"7308","DOI":"10.3390\/ijms21197308","article-title":"Seminal Plasma Transcriptome and Proteome: Towards a Molecular Approach in the Diagnosis of Idiopathic Male Infertility","volume":"21","author":"Cannarella","year":"2020","journal-title":"Int J Mol Sci"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.3390\/jcm8060809","article-title":"Effects of Insulin on Porcine Neonatal Sertoli Cell Responsiveness to FSH In Vitro","volume":"8","author":"Cannarella","year":"2019","journal-title":"J Clin Med"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.26355\/eurrev_201907_18346","article-title":"FSH Treatment for Normogonadotropic Male Infertility: A Synergistic Role for Metformin","volume":"23","author":"La Vignera","year":"2019","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1111\/andr.12659","article-title":"Risk Behaviours and Alcohol in Adolescence are Negatively Associated With Testicular Volume: Results From the Amico-Andrologo Survey","volume":"7","author":"Gianfrilli","year":"2019","journal-title":"Andrology"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.3390\/jcm8091414","article-title":"The Risky Health Behaviours of Male Adolescents in the Southern Italian Region: Implications for Sexual and Reproductive Disease","volume":"8","author":"Perri","year":"2019","journal-title":"J Clin Med"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.3390\/jcm8060811","article-title":"Effects of GH and IGF1 on Basal and FSH-Modulated Porcine Sertoli Cells in-Vitro","volume":"8","author":"Cannarella","year":"2019","journal-title":"J Clin Med"}],"container-title":["Frontiers in Endocrinology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fendo.2021.797228\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,11,17]],"date-time":"2021-11-17T07:05:35Z","timestamp":1637132735000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fendo.2021.797228\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11,17]]},"references-count":10,"alternative-id":["10.3389\/fendo.2021.797228"],"URL":"https:\/\/doi.org\/10.3389\/fendo.2021.797228","relation":{},"ISSN":["1664-2392"],"issn-type":[{"type":"electronic","value":"1664-2392"}],"subject":[],"published":{"date-parts":[[2021,11,17]]},"article-number":"797228"}}