{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T15:35:03Z","timestamp":1784907303358,"version":"3.55.0"},"reference-count":11,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2022,11,28]],"date-time":"2022-11-28T00:00:00Z","timestamp":1669593600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Endocrinol."],"abstract":"<jats:p>There is currently no universally accepted name for inflammatory disease of the eye and orbit associated with thyroid autoimmune disease. Variability in terminology impedes the evaluation of scientific literature and clinical collaboration and can affect patients\u2019 understanding of a disease process. The goals of this perspective article are 1. To compare the frequency of different terms used for eye disease associated with autoimmune thyroid disease in the scientific literature between 2000, 2010 and 2020 publications; 2. To investigate potential associations of terminology with author and journal specialty, and multidisciplinary vs. mono-disciplinary author teams; 3. To determine preferential terms used by professional societies; and 4. To propose standardized terminology based on our data analysis. The methods for this study included review of all English language articles listed in PubMed, with publication dates in the years 2000, 2010 and 2020, that included one of 6 terms currently used to describe eye disease associated with autoimmune thyroid disease. Characteristics pertaining to authors, journals, and article type were recorded. Results showed that the most used term in the 2000 literature was Graves\u2019 Ophthalmopathy (61%). In the 2010 literature, Graves\u2019 Orbitopathy (31%) became most common, followed by Graves\u2019 Ophthalmopathy (30%). Between 2010 and 2020, thyroid eye disease (37%) became the most common term, followed by Graves\u2019 Orbitopathy (35%). This perspective article proposes \u201cthyroid eye disease\u201d (TED) as the preferred name for this entity and discusses supporting terminology patterns and trends over time in scientific literature and in professional societies.<\/jats:p>","DOI":"10.3389\/fendo.2022.1083886","type":"journal-article","created":{"date-parts":[[2022,11,28]],"date-time":"2022-11-28T02:37:03Z","timestamp":1669603023000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":8,"title":["Thyroid eye disease or Graves\u2019 orbitopathy: What name to use, and why it matters"],"prefix":"10.3389","volume":"13","author":[{"given":"Lilly H.","family":"Wagner","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth A.","family":"Bradley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea A.","family":"Tooley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanhan","family":"Ren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kharisa N.","family":"Rachmasari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marius N.","family":"Stan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2022,11,28]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoto.2018.1272","article-title":"Effect of a change in papillary thyroid cancer terminology on anxiety levels and treatment preferences: A randomized crossover trial","volume":"144","author":"Nickel","year":"2018","journal-title":"JAMA Otolaryngol Head Neck 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hypothyroidism, and euthyroidism in thyroid eye disease: a systematic review of the literature","volume":"9","author":"Mu\u00f1oz-Ortiz","year":"2020","journal-title":"Syst Rev"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2018.0665","article-title":"Knowledge of thyroid eye disease in graves' disease patients with and without orbitopathy","volume":"29","author":"Edmunds MR","year":"2019","journal-title":"Thyroid"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcjo.2020.06.004","article-title":"Nomenclature: thyroid-associated orbitopathy, graves ophthalmopathy, or thyroid eye disease","volume":"56","author":"Ing","year":"2021","journal-title":"Can J Ophthalmol"},{"key":"B11","unstructured":"Graves' Orbitopathy"}],"container-title":["Frontiers in 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