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Thanks to these achievements, CAH patients are now in their adulthood, but an increased incidence of cardiovascular risk factors has been reported compared to general population in this stage of life. The aim of CAH treatment is to both prevent adrenal insufficiency and suppress androgen excess; in this delicate balance, under- as well as overtreatment might be equally harmful to long-term cardiovascular health. This work examines the prevalence of metabolic features and cardiovascular events, their correlation with hormone levels and GC replacement regimen in CAH patients and focuses on precocious markers to early detect patients at higher risk and new potential treatment approaches.<\/jats:p>","DOI":"10.3389\/fendo.2022.934675","type":"journal-article","created":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T05:01:01Z","timestamp":1659330061000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":23,"title":["Metabolic syndrome and cardiovascular morbidity in patients with congenital adrenal 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