{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T11:15:59Z","timestamp":1787829359612,"version":"build-2784847793"},"reference-count":18,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2023,9,8]],"date-time":"2023-09-08T00:00:00Z","timestamp":1694131200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Endocrinol."],"abstract":"<jats:p>Uremic tumoral calcinosis (UTC) is an uncommon and severe complication of hemodialysis therapy. The most important pathogenic factor involved in UTC is an increase in calcium-phosphorus products. We report here a patient undergoing hemodialysis for renal failure caused by hypertensive nephropathy who presented multiple UTCs in the right shoulder, left elbow and wrist. After surgical excision, they all recurred, with a similar UTC in the left shoulder. By observing the imaging features of various imaging examinations during the whole period of this case, including X-ray, computed tomography (CT), magnetic resonance imaging (MRI), and single-photon emission computed tomography (SPECT), we highlight the importance of imaging for evaluating the state of UTC regarding treatment options, further deepening our understanding of the imaging manifestations for this disease and their clinical significance.<\/jats:p>","DOI":"10.3389\/fendo.2023.1249680","type":"journal-article","created":{"date-parts":[[2023,9,11]],"date-time":"2023-09-11T12:26:55Z","timestamp":1694435215000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":2,"title":["Multiple uremic tumoral calcinosis in periarticular soft tissues with chronic renal failure: a case report"],"prefix":"10.3389","volume":"14","author":[{"given":"Lijin","family":"He","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meifang","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chenlan","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kunlong","family":"Yan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chengmin","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2023,9,8]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"26","DOI":"10.3171\/2015.12.Spine151085","article-title":"Uremic tumoral calcinosis in the cervical spine: case report","volume":"25","author":"Fatehi","year":"2016","journal-title":"J Neurosurg Spine"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.12998\/wjcc.v2.i9.409","article-title":"Review of tumoral calcinosis: A rare clinico-pathological entity","volume":"2","author":"Fathi","year":"2014","journal-title":"World J Clin cases"},{"key":"B3","doi-asserted-by":"publisher","first-page":"E1133","DOI":"10.1503\/cmaj.200104","article-title":"Uremic tumoral calcinosis of the cervical spine","volume":"192","author":"Kendal","year":"2020","journal-title":"CMAJ: Can Med Assoc J = J l\u2019Associat medicale Can"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1097\/00003072-199512000-00026","article-title":"Tumoral calcinosis-like metastatic calcification in a patient with renal osteodystrophy: CT and scintigraphic appearances","volume":"20","author":"Kobayashi","year":"1995","journal-title":"Clin Nucl Med"},{"key":"B5","article-title":"Surgical complications associated with extensive tumoral calcinosis","volume":"40","author":"King","year":"2011","journal-title":"Am J orthopedics (Belle Mead NJ)"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1007\/s00402-007-0310-2","article-title":"A case of symptomatic tumoral calcinosis on the great toe and review of the literature","volume":"128","author":"Kadowaki","year":"2008","journal-title":"Arch orthopaedic Trauma Surg"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2021-247613","article-title":"Sedimentation sign: a classical finding on tumorous calcinosis","volume":"15","author":"Pires","year":"2022","journal-title":"BMJ Case Rep"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1016\/j.pjnns.2016.12.001","article-title":"Tumoral calcinosis of the cervical spine in a dialysis patient. 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