{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T23:10:38Z","timestamp":1791846638041,"version":"4.3.4"},"reference-count":81,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2024,6,24]],"date-time":"2024-06-24T00:00:00Z","timestamp":1719187200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Endocrinol."],"abstract":"<jats:p>Diabetes, a multifaceted metabolic disorder, poses a significant global health burden with its increasing prevalence and associated complications, such as diabetic nephropathy, diabetic retinopathy, diabetic cardiomyopathy, and diabetic angiopathy. Recent studies have highlighted the intricate interplay between N<jats:sup>6<\/jats:sup>-methyladenosine (m<jats:sup>6<\/jats:sup>A) and non-coding RNAs (ncRNAs) in key pathways implicated in these diabetes complications, like cell apoptosis, oxidative stress, and inflammation. Thus, understanding the mechanistic insights into how m<jats:sup>6<\/jats:sup>A dysregulation impacts the expression and function of ncRNAs opens new avenues for therapeutic interventions targeting the m<jats:sup>6<\/jats:sup>A-ncRNAs axis in diabetes complications. This review explores the regulatory roles of m<jats:sup>6<\/jats:sup>A modifications and ncRNAs, and stresses the role of the m<jats:sup>6<\/jats:sup>A-ncRNA axis in diabetes complications, providing a therapeutic potential for these diseases.<\/jats:p>","DOI":"10.3389\/fendo.2024.1426380","type":"journal-article","created":{"date-parts":[[2024,6,24]],"date-time":"2024-06-24T04:28:31Z","timestamp":1719203311000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":6,"title":["The m6A-ncRNAs axis in diabetes complications: novel mechanism and therapeutic 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