{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T14:06:04Z","timestamp":1790690764209,"version":"4.1.0"},"reference-count":32,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2024,12,16]],"date-time":"2024-12-16T00:00:00Z","timestamp":1734307200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Endocrinol."],"abstract":"<jats:sec><jats:title>Purpose<\/jats:title><jats:p>Infertility is affecting more and more couples of appropriate age. Hysteroscopy (HSC) has certain effects on the uncompleted pregnancy and live birth caused by uterine microenvironment. Based on the evidence, this paper systematically evaluates the effectiveness and safety of HSC intervention on the fertility outcome of female infertility.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Randomised controlled trials (RCTS) of hysteroscopy intervention in female infertility were included in the literature database. The retrieval time was from the establishment of the database to December 10, 2022. RevMan 5.4 software was used for statistical analysis to study the effects of HSC on clinical pregnancy rate, live birth rate and abortion rate.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 14 RCTS were included. Five studies evaluated the effect of HSC on live birth rate, and HSC had an overall positive effect on live birth rate. Fourteen studies evaluated the effect of HSC on clinical pregnancy rates, and preoperative HSC was associated with significant improvements in pregnancy rates for both first-time IVF\/ICSI patients and repeat IVF\/ICSI patients. Eight studies showed no significant difference in the effect of HSC on miscarriage rates.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>As a visual examination\/treatment technique, HSC can improve the clinical pregnancy rate and live birth rate in most studies, while the risk of abortion is within the acceptable range, and can be used as a recommended examination method for infertile women.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fendo.2024.1489783","type":"journal-article","created":{"date-parts":[[2024,12,16]],"date-time":"2024-12-16T12:23:27Z","timestamp":1734351807000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":8,"title":["Whether hysteroscopy improves fertility outcomes in infertile women: a meta-analysis and systematic review"],"prefix":"10.3389","volume":"15","author":[{"given":"Yidi","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zunhao","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chanchan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiuxiang","family":"Teng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junqin","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2024,12,16]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2005.08.066","article-title":"International disparities in access to infertility services","volume":"85","author":"Nachtigall","year":"2006","journal-title":"Fertil Steril"},{"key":"B2","volume-title":"Infertility prevalence estimates, 1990\u20132021","year":"2023"},{"key":"B3","doi-asserted-by":"publisher","first-page":"393","DOI":"10.1016\/j.fertnstert.2017.06.005","article-title":"The international glossary on infertility and fertility care, 2017","volume":"108","author":"Zegers-Hochschild","year":"2017","journal-title":"Fertil Steril"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.3760\/cma.j.issn.0529-567x.2019.08.001","article-title":"Infertility diagnosis guidelines","volume":"54","author":"Chen","year":"2019","journal-title":"Chin J Obstet Gynecol"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2015.03.019","article-title":"Diagnostic evaluation of the infertile female: a committee opinion","volume":"103","year":"2015","journal-title":"Fertil Steril"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD009461.pub4","article-title":"Hysteroscopy for treating subfertility associated with suspected major uterine cavity abnormalities","volume":"12","author":"Bosteels","year":"2018","journal-title":"Cochrane Database Syst Rev"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dmx019","article-title":"Baseline anatomical assessment of the uterus and ovaries in infertile women: a systematic review of the evidence on which assessment methods are the safest and most effective in terms of improving fertility outcomes","volume":"23","author":"Armstrong","year":"2017","journal-title":"Hum Reprod Update"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2019.06.031","article-title":"Hysteroscopy and why macroscopic uterine factors matter for fertility","volume":"112","author":"Parry","year":"2019","journal-title":"Fertil Steril"},{"key":"B9","article-title":"Fertility: assessment and treatment for people with fertility problems","year":"2013","journal-title":"Natl Institute Health Clin Excellence"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmig.2018.10.024","article-title":"Hysteroscopic resection of endometrial polyps and assisted reproductive technology pregnancy outcomes compared with no treatment: A systematic review","volume":"26","author":"Zhang","year":"2019","journal-title":"J Minim Invasive Gynecol"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000014075","article-title":"Effect of hysteroscopy before starting in-vitro fertilization for women with recurrent implantation failure: A meta-analysis and systematic review","volume":"98","author":"Mao","year":"2019","journal-title":"Med (Baltimore)"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.4069\/kjwhn.2020.12.13","article-title":"The effects of diagnostic hysteroscopy on the reproductive outcomes of infertile women without intrauterine pathologies: a systematic review and meta-analysis","volume":"26","author":"Yang","year":"2020","journal-title":"Korean J Women Health Nurs"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1016\/j.jogoh.2021.102109","article-title":"Office hysteroscopy before first in vitro fertilization. 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