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Endocrinol."],"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>This study aimed to explore the cut-off value of 10 obesity indicators, including BF% (Body Fat Ratio, BF%), BMI (Body Mass Index, BMI), WHR (Waist-to-Hip Ratio, WHR), WHtR (Waist-to-Height Ratio, WHtR), BAI (Body Adiposity Index, BAI), OBD (Obesity Degree, OBD), CI (Conicity Index,CI), AVI (Abdominal Volume Index, AVI), ABSI (A Body Shape Index, ABSI) and BRI (Body Roundness Index, BRI), and investigate their relationship between different anthropometric indices of obesity indicators and their correlation to hypertension, diabetes, and dyslipidemia in rural residents aged 35\u201374 years in Ningxia, an autonomous region of northwest China.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The study participants were interviewed by questionnaire (including demographic characteristics such as age, education status, economic status, and lifestyle variables such as exercise frequency, smoke, alcohol, tea, spice, and vinegar consumption), bio-impedance body composition analysis, and blood laboratory test. The t-test and chi-square test were used to compare the characteristics of different groups, and the receiver operating characteristic curve was used to analyze the correlation of different indicators and explore their cut-off values.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The study comprised 14,926 participants, of whom 39.80% (5948\/14,926) were male, and the mean age of the study population was 56.75 \u00b1 9.74 years. The waist circumference had the greatest influence on obesity indicators, and BMI, AVI, and BRI are most susceptible to anthropometric indicators. WHtR had the largest AUC (Area Under the ROC Curves, AUC) for predicting obesity in both male and female. In addition, we provided a recommended cut-off value of BMI, WHR, WHtR, BAI, OBD, CI, AVI, ABSI and BRI. WHtR had the largest AUC for predicting diabetes, hypertension, and dyslipidemia, while WHtR served as a good predictive indicator (all P&amp;lt;0.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Waist circumference is closely related to obesity. Therefore, there is a great significance to carry out long-term health management education among the population, change the unhealthy lifestyle and promote the metabolic health for the primary prevention of cardiovascular diseases.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fendo.2025.1346193","type":"journal-article","created":{"date-parts":[[2025,6,9]],"date-time":"2025-06-09T04:10:49Z","timestamp":1749442249000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":8,"title":["Different obesity indicators and their correlation with hypertension, diabetes, and dyslipidemia in 35\u201374 years rural residents in Northwest 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