{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T16:00:46Z","timestamp":1792598446827,"version":"4.5.0"},"reference-count":86,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T00:00:00Z","timestamp":1759190400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Endocrinol."],"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>To develop and validate a user-oriented nomogram of suicide risk in thyroid cancer patients to enable clinicians to identify and intervene in a timely manner with high-risk subgroups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was a retrospective, population-based cohort study in which patients with thyroid cancer diagnosed from the Surveillance, Epidemiology, and End Results (SEER) database between 2000 and 2020 were include. Optimized features were screened by the least absolute shrinkage and selection operator (LASSO) regression model. Subsequently, we selected variables with nonzero coefficients, entered them into a Cox proportional hazards regression model and constructed a visualized nomogram model predicting suicide. We implemented receiver operating characteristic curves (ROC), calibration curves, decision curve analysis (DCA), and internal validation to assess the discrimination, calibration, clinical applicability, and generalizability of the nomogram.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>To our knowledge, this is the first nomogram specifically designed for thyroid cancer patients, integrating histopathological, therapeutic, and socioeconomic predictors. Furthermore, the calibration curves for this nomogram fit well with the diagonal, and the C-indexes for the training and testing sets were 0.760 and 0.724, respectively, and the decision curve analysis indicated clinical benefit.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This study successfully identified risk factors for suicide in patients with thyroid cancer and developed a nomogram that provides patients with an individualized, quantifiable assessment of suicide risk and assists clinicians in identifying and intervening in potential suicides.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fendo.2025.1392283","type":"journal-article","created":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T05:29:47Z","timestamp":1759210187000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":2,"title":["Development and validation of a nomogram for predicting suicide risk factors in thyroid cancer patients following diagnosis: a population-based retrospective study"],"prefix":"10.3389","volume":"16","author":[{"given":"Jie","family":"Zhou","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengjie","family":"Tian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiangchen","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lingyi","family":"Xiong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinlong","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengfan","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinjun","family":"Liang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaozhong","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2025,9,30]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21660","article-title":"Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries","volume":"71","author":"Sung","year":"2021","journal-title":"CA Cancer J Clin"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-8587(22)00035-3","article-title":"The epidemiological landscape of thyroid cancer worldwide: GLOBOCAN estimates for incidence and mortality rates in 2020","volume":"10","author":"Pizzato","year":"2022","journal-title":"Lancet Diabetes Endocrinol"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)30172-6","article-title":"Thyroid cancer","volume":"388","author":"Cabanillas","year":"2016","journal-title":"Lancet"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoto.2022.0660","article-title":"The cost and financial burden of thyroid cancer on patients in the US: A review and directions for future research","volume":"148","author":"Uppal","year":"2022","journal-title":"JAMA Otolaryngol Head Neck Surg"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1902944","article-title":"Suicide","volume":"382","author":"Fazel","year":"2020","journal-title":"N Engl J Med"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-med-042220-015032","article-title":"Contemporary management of thyroid nodules","volume":"73","author":"Kobaly","year":"2022","journal-title":"Annu Rev Med"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1002\/cam4.2813","article-title":"Causes of death among cancer patients in the era of cancer survivorship in Korea: Attention to the suicide and cardiovascular mortality","volume":"9","author":"Oh","year":"2020","journal-title":"Cancer Med"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.31675","article-title":"Suicide risk among cancer survivors: Head and neck versus other cancers","volume":"124","author":"Osazuwa-Peters","year":"2018","journal-title":"Cancer"},{"key":"B9","doi-asserted-by":"publisher","first-page":"111173","DOI":"10.1016\/j.mce.2021.111173","article-title":"The hypothalamus-pituitary-thyroid (HPT)-axis and its role in physiology and pathophysiology of other hypothalamus-pituitary functions","volume":"525","author":"Feldt-Rasmussen","year":"2021","journal-title":"Mol Cell Endocrinol"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2016.0632","article-title":"Papillary thyroid cancer: the good and bad of the \u201cGood cancer","volume":"27","author":"Randle","year":"2017","journal-title":"Thyroid"},{"key":"B11","doi-asserted-by":"publisher","first-page":"114180","DOI":"10.1016\/j.socscimed.2021.114180","article-title":"Still ready to give up on life? A longitudinal phenomenological study into wishes to die among older adults","volume":"284","author":"van Wijngaarden","year":"2021","journal-title":"Soc Sci Med"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoto.2015.2480","article-title":"Incidence of suicide in patients with head and neck cancer","volume":"141","author":"Kam","year":"2015","journal-title":"JAMA Otolaryngol Head Neck Surg"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoto.2021.1728","article-title":"Incidence and risk of suicide among patients with head and neck cancer in rural, urban, and metropolitan areas","volume":"147","author":"Osazuwa-Peters","year":"2021","journal-title":"JAMA Otolaryngol Head Neck Surg"},{"key":"B14","doi-asserted-by":"publisher","first-page":"299","DOI":"10.1037\/a0029940","article-title":"Psychological factors associated with head and neck cancer treatment and survivorship: evidence and opportunities for behavioral medicine","volume":"81","author":"Howren","year":"2013","journal-title":"J Consult Clin Psychol"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2015.0098","article-title":"Risk factors for decreased quality of life in thyroid cancer survivors: initial findings from the north American thyroid cancer survivorship study","volume":"25","author":"Aschebrook-Kilfoy","year":"2015","journal-title":"Thyroid"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-015-3300-5","article-title":"Quality of life in thyroid cancer is similar to that of other cancers with worse survival","volume":"40","author":"Applewhite","year":"2016","journal-title":"World J Surg"},{"key":"B17","doi-asserted-by":"publisher","first-page":"114119","DOI":"10.1016\/j.psychres.2021.114119","article-title":"Incidence of suicide mortality among childhood cancer survivors: A population-based retrospective study","volume":"304","author":"Fu","year":"2021","journal-title":"Psychiatry Res"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2022.0067","article-title":"Predictors of anxiety and depression in differentiated thyroid cancer survivors: results of a cross-sectional study","volume":"32","author":"Noto","year":"2022","journal-title":"Thyroid"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2019.03.006","article-title":"Post-thyroidectomy neck appearance and impact on quality of life in thyroid cancer survivors","volume":"165","author":"Kurumety","year":"2019","journal-title":"Surgery"},{"key":"B20","doi-asserted-by":"publisher","first-page":"88","DOI":"10.1046\/j.1473-2165.2002.00027.x","article-title":"The body as art","volume":"1","author":"Barker","year":"2002","journal-title":"J Cosmet Dermatol"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2019.04.068","article-title":"Energy level and fatigue after surgery for thyroid cancer: A population-based study of patient-reported outcomes","volume":"167","author":"Hughes","year":"2020","journal-title":"Surgery"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1001\/archoto.2009.16","article-title":"Clinical predictors of quality of life in patients with initial differentiated thyroid cancers","volume":"135","author":"Almeida","year":"2009","journal-title":"Arch Otolaryngol Head Neck Surg"},{"key":"B23","doi-asserted-by":"publisher","first-page":"djv314","DOI":"10.1093\/jnci\/djv314","article-title":"Use of radioactive iodine for thyroid cancer and risk of second primary Malignancy: A nationwide population-based study","volume":"108","author":"Teng","year":"2016","journal-title":"J Natl Cancer Inst"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1080\/10705511.2016.1154793","article-title":"Regularized structural equation modeling","volume":"23","author":"Jacobucci","year":"2016","journal-title":"Struct Equ Modeling"},{"key":"B25","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1186\/s12938-018-0568-3","article-title":"Machine learning approaches for predicting high cost high need patient expenditures in health care","volume":"17","author":"Yang","year":"2018","journal-title":"BioMed Eng Online"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2003.09.017","article-title":"Interpreting statistics in medical literature: a vade mecum for surgeons","volume":"198","author":"Guller","year":"2004","journal-title":"J Am Coll Surg"},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjc.6601118","article-title":"Survival analysis part I: basic concepts and first analyses","volume":"89","author":"Clark","year":"2003","journal-title":"Br J Cancer"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjc.6601119","article-title":"Survival analysis part II: multivariate data analysis\u2013an introduction to concepts and methods","volume":"89","author":"Bradburn","year":"2003","journal-title":"Br J Cancer"},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.3109\/0284186X.2012.741326","article-title":"Health-related quality of life and disease specific symptoms in long-term thyroid cancer survivors: a study from the population-based PROFILES registry","volume":"52","author":"Husson","year":"2013","journal-title":"Acta Oncol"},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-014-3846-8","article-title":"Total thyroidectomy is associated with increased risk of complications for low- and high-volume surgeons","volume":"21","author":"Hauch","year":"2014","journal-title":"Ann Surg Oncol"},{"key":"B31","doi-asserted-by":"publisher","DOI":"10.1007\/s12020-018-1649-6","article-title":"Cognitive functioning and quality of life in patients with Hashimoto thyroiditis on long-term levothyroxine replacement","volume":"62","author":"Djurovic","year":"2018","journal-title":"Endocrine"},{"key":"B32","doi-asserted-by":"publisher","DOI":"10.1001\/jamasurg.2021.6442","article-title":"Association of total thyroidectomy or thyroid lobectomy with the quality of life in patients with differentiated thyroid cancer with low to intermediate risk of recurrence","volume":"157","author":"Chen","year":"2022","journal-title":"JAMA Surg"},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.1515\/med-2019-0008","article-title":"The link between thyroid autoimmunity, depression and bipolar disorder","volume":"14","author":"Jucevi\u010di\u016bt\u0117","year":"2019","journal-title":"Open Med (Wars)"},{"key":"B34","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1001\/jamapsychiatry.2018.3181","article-title":"Risk of suicide after cancer diagnosis in England","volume":"76","author":"Henson","year":"2019","journal-title":"JAMA Psychiatry"},{"key":"B35","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2023.11.086","article-title":"Development and validation of a nomogram for predicting suicide risk and prognostic factors in bladder cancer patients following diagnosis: A population-based retrospective study","volume":"347","author":"Liu","year":"2024","journal-title":"J Affect Disord"},{"key":"B36","doi-asserted-by":"publisher","DOI":"10.1192\/j.eurpsy.2022.2320","article-title":"Social isolation and suicide risk: Literature review and perspectives","volume":"65","author":"Motillon-Toudic","year":"2022","journal-title":"Eur Psychiatry"},{"key":"B37","doi-asserted-by":"publisher","first-page":"193","DOI":"10.1016\/j.neubiorev.2021.04.011","article-title":"Suicidal behaviour in older age: A systematic review of risk factors associated to suicide attempts and completed suicides","volume":"127","author":"Beghi","year":"2021","journal-title":"Neurosci Biobehav Rev"},{"key":"B38","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-clinpsy-032511-143109","article-title":"Emotion regulation and psychopathology: the role of gender","volume":"8","author":"Nolen-Hoeksema","year":"2012","journal-title":"Annu Rev Clin Psychol"},{"key":"B39","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/S0165-0327(01)00379-2","article-title":"Barriers to help-seeking by men: a review of sociocultural and clinical literature with particular reference to depression","volume":"71","author":"M\u00f6ller-Leimk\u00fchler","year":"2002","journal-title":"J Affect Disord"},{"key":"B40","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2021.0361","article-title":"Sex differences in differentiated thyroid cancer","volume":"32","author":"Shobab","year":"2022","journal-title":"Thyroid"},{"key":"B41","doi-asserted-by":"publisher","DOI":"10.1016\/j.critrevonc.2010.05.005","article-title":"Suicide and cancer: where do we go from here","volume":"78","author":"Spoletini","year":"2011","journal-title":"Crit Rev Oncol Hematol"},{"key":"B42","doi-asserted-by":"publisher","DOI":"10.1177\/1049732318800003","article-title":"Unpacking social isolation in men\u2019s suicidality","volume":"29","author":"Oliffe","year":"2019","journal-title":"Qual Health Res"},{"key":"B43","doi-asserted-by":"publisher","DOI":"10.1177\/1557988316679576","article-title":"Injury, interiority, and isolation in men\u2019s suicidality","volume":"11","author":"Oliffe","year":"2017","journal-title":"Am J Mens Health"},{"key":"B44","doi-asserted-by":"publisher","DOI":"10.1177\/107327480000700302","article-title":"Prognostic indicators in differentiated thyroid carcinoma","volume":"7","author":"Dean","year":"2000","journal-title":"Cancer Control"},{"key":"B45","doi-asserted-by":"publisher","DOI":"10.1210\/jcem.86.4.7407","article-title":"Clinical review 128: Current approaches to primary therapy for papillary and follicular thyroid cancer","volume":"86","author":"Mazzaferri","year":"2001","journal-title":"J Clin Endocrinol Metab"},{"key":"B46","doi-asserted-by":"publisher","DOI":"10.1080\/13607863.2019.1603284","article-title":"Cross-national prevalence and factors associated with suicide ideation and attempts in older and young-and-middle age people","volume":"24","author":"Cabello","year":"2020","journal-title":"Aging Ment Health"},{"key":"B47","doi-asserted-by":"publisher","DOI":"10.1177\/154230500305700308","article-title":"The experience of spirituality in the psycho-social adaptation of cancer survivors","volume":"57","author":"Samson","year":"2003","journal-title":"J Pastoral Care Counsel"},{"key":"B48","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1521\/suli.32.1.1.22184","article-title":"A case control study of suicide and attempted suicide in older adults","volume":"32","author":"Beautrais","year":"2002","journal-title":"Suicide Life Threat Behav"},{"key":"B49","doi-asserted-by":"publisher","first-page":"232","DOI":"10.1038\/s41398-020-00874-7","article-title":"Whole-blood expression of inflammasome- and glucocorticoid-related mRNAs correctly separates treatment-resistant depressed patients from drug-free and responsive patients in the BIODEP study","volume":"10","author":"Cattaneo","year":"2020","journal-title":"Transl Psychiatry"},{"key":"B50","article-title":"Health care contact prior to suicide attempts in older adults. A field study in Galicia, Spain","volume":"48","author":"Soriano Barcel\u00f3","year":"2020","journal-title":"Actas Esp Psiquiatr"},{"key":"B51","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.1998.396","article-title":"Predictors of patients\u2019 mental adjustment to cancer: patient characteristics and social support","volume":"77","author":"Akechi","year":"1998","journal-title":"Br J Cancer"},{"key":"B52","doi-asserted-by":"publisher","DOI":"10.1002\/pon.1136","article-title":"Familial social support and depression in breast cancer: an exploratory study on a Pakistani sample","volume":"16","author":"Nausheen","year":"2007","journal-title":"Psychooncology"},{"key":"B53","doi-asserted-by":"publisher","DOI":"10.1007\/s11764-017-0627-y","article-title":"Benefits of marriage on relative and conditional relative cancer survival differ between males and females in the USA","volume":"11","author":"Merrill","year":"2017","journal-title":"J Cancer Surviv"},{"key":"B54","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2023.10.007","article-title":"The temporal relationship between marriage and risk for suicidal ideation","volume":"343","author":"Stephenson","year":"2023","journal-title":"J Affect Disord"},{"key":"B55","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3999(01)00235-5","article-title":"The influence of social support on depressive symptoms in cancer patients: age and gender differences","volume":"52","author":"Hann","year":"2002","journal-title":"J Psychosom Res"},{"key":"B56","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2013.49.6489","article-title":"Marital status and survival in patients with cancer","volume":"31","author":"Aizer","year":"2013","journal-title":"J Clin Oncol"},{"key":"B57","doi-asserted-by":"publisher","DOI":"10.1016\/j.socscimed.2017.11.053","article-title":"Marital status integration and suicide: A meta-analysis and meta-regression","volume":"197","author":"Kyung-Sook","year":"2018","journal-title":"Soc Sci Med"},{"key":"B58","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1177\/0030222817715756","article-title":"Suicide trends according to age, gender, and marital status in South Korea","volume":"79","author":"Kim","year":"2019","journal-title":"Omega (Westport)"},{"key":"B59","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2014.12816","article-title":"Rate of suicide increases in middle age: primary care key to suicide prevention","volume":"312","author":"Mann","year":"2014","journal-title":"Jama"},{"key":"B60","doi-asserted-by":"publisher","DOI":"10.1016\/j.archger.2010.02.012","article-title":"Suicide attempts and burden of physical illness among depressed elderly inpatients","volume":"52","author":"Bergman Levy","year":"2011","journal-title":"Arch Gerontol Geriatr"},{"key":"B61","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1027\/0227-5910\/a000054","article-title":"Suicide risk and its relationship to change in marital status","volume":"32","author":"Ro\u0161kar","year":"2011","journal-title":"Crisis"},{"key":"B62","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s12552-012-9080-8","article-title":"The moderating effects of skin color and ethnic identity affirmation on suicide risk among low-SES African American women","volume":"5","author":"Perry","year":"2013","journal-title":"Race Soc Probl"},{"key":"B63","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.v67n0402","article-title":"Suicide rates in relation to health care access in the United States: an ecological study","volume":"67","author":"Tondo","year":"2006","journal-title":"J Clin Psychiatry"},{"key":"B64","doi-asserted-by":"publisher","DOI":"10.1111\/sltb.12023","article-title":"Social integration and suicide-related ideation from a social network perspective: a longitudinal study among inner-city African Americans","volume":"43","author":"Kuramoto","year":"2013","journal-title":"Suicide Life Threat Behav"},{"key":"B65","doi-asserted-by":"publisher","DOI":"10.1521\/suli.2005.35.6.615","article-title":"Suicidality in African American men: the roles of southern residence, religiosity, and social support","volume":"35","author":"Wingate","year":"2005","journal-title":"Suicide Life Threat Behav"},{"key":"B66","doi-asserted-by":"publisher","DOI":"10.1007\/s00127-005-0865-6","article-title":"Social environment factors associated with suicide attempt among low-income African Americans: the protective role of family relationships and social support","volume":"40","author":"Compton","year":"2005","journal-title":"Soc Psychiatry Psychiatr Epidemiol"},{"key":"B67","doi-asserted-by":"publisher","DOI":"10.1521\/suli.2010.40.2.170","article-title":"The Great Black Hope: Hope and its relation to suicide risk among African Americans","volume":"40","author":"Davidson","year":"2010","journal-title":"Suicide Life Threat Behav"},{"key":"B68","doi-asserted-by":"publisher","DOI":"10.1037\/a0029594","article-title":"Racial identity and reasons for living in African American female suicide attempters","volume":"18","author":"Street","year":"2012","journal-title":"Cultur Divers Ethnic Minor Psychol"},{"key":"B69","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2013.0308","article-title":"Incidence of differentiated thyroid cancer by socioeconomic status and urban residence: Canada 1991-2006","volume":"24","author":"Guay","year":"2014","journal-title":"Thyroid"},{"key":"B70","doi-asserted-by":"publisher","DOI":"10.1111\/sltb.12390","article-title":"Rural\/Urban disparities in adolescent nonfatal suicidal ideation and suicide attempt: A population-based study","volume":"48","author":"Goldman-Mellor","year":"2018","journal-title":"Suicide Life Threat Behav"},{"key":"B71","doi-asserted-by":"publisher","DOI":"10.1017\/S2045796018000124","article-title":"Subjective wellbeing, suicide and socioeconomic factors: an ecological analysis in Hong Kong","volume":"28","author":"Hsu","year":"2019","journal-title":"Epidemiol Psychiatr Sci"},{"key":"B72","doi-asserted-by":"publisher","first-page":"365","DOI":"10.1186\/s12888-017-1532-7","article-title":"The effect of seasonal changes and climatic factors on suicide attempts of young people","volume":"17","author":"Akkaya-Kalayci","year":"2017","journal-title":"BMC Psychiatry"},{"key":"B73","doi-asserted-by":"publisher","DOI":"10.1001\/jamapsychiatry.2014.1198","article-title":"Direct effect of sunshine on suicide","volume":"71","author":"Vyssoki","year":"2014","journal-title":"JAMA Psychiatry"},{"key":"B74","doi-asserted-by":"publisher","DOI":"10.1016\/j.ypmed.2017.04.032","article-title":"Rising longitudinal trajectories in suicide rates: The role of firearm suicide rates and firearm legislation","volume":"100","author":"Anestis","year":"2017","journal-title":"Prev Med"},{"key":"B75","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.94.10.1750","article-title":"Urban-rural shifts in intentional firearm death: different causes, same results","volume":"94","author":"Branas","year":"2004","journal-title":"Am J Public Health"},{"key":"B76","doi-asserted-by":"publisher","first-page":"1167","DOI":"10.1111\/j.1540-6237.2009.00652.x","article-title":"Adult suicide mortality in the United States: marital status, family size, socioeconomic status, and differences by sex","volume":"90","author":"Denney","year":"2009","journal-title":"Soc Sci Q"},{"key":"B77","doi-asserted-by":"publisher","first-page":"4210","DOI":"10.22605\/RRH4210","article-title":"Socioeconomic disparities in head and neck cancer patients\u2019 access to cancer treatment centers","volume":"17","author":"Walker","year":"2017","journal-title":"Rural Remote Health"},{"key":"B78","doi-asserted-by":"publisher","first-page":"974","DOI":"10.1186\/s12913-019-4815-5","article-title":"Access to specialty healthcare in urban versus rural US populations: a systematic literature review","volume":"19","author":"Cyr","year":"2019","journal-title":"BMC Health Serv Res"},{"key":"B79","doi-asserted-by":"publisher","DOI":"10.1017\/cts.2020.42","article-title":"A call to action to address rural mental health disparities","volume":"4","author":"Morales","year":"2020","journal-title":"J Clin Transl Sci"},{"key":"B80","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1146\/annurev.publhealth.29.020907.090821","article-title":"Ecologic studies revisited","volume":"29","author":"Wakefield","year":"2008","journal-title":"Annu Rev Public Health"},{"key":"B81","doi-asserted-by":"publisher","DOI":"10.1002\/pon.3524","article-title":"Intentions in wishes to die: analysis and a typology\u2013a report of 30 qualitative case studies of terminally ill cancer patients in palliative care","volume":"23","author":"Ohnsorge","year":"2014","journal-title":"Psychooncology"},{"key":"B82","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1186\/1472-684X-13-38","article-title":"What a wish to die can mean: reasons, meanings and functions of wishes to die, reported from 30 qualitative case studies of terminally ill cancer patients in palliative care","volume":"13","author":"Ohnsorge","year":"2014","journal-title":"BMC Palliat Care"},{"key":"B83","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2022.833965","article-title":"Suicide and accidental death among women with primary ovarian cancer: A population-based study","volume":"9","author":"Chen","year":"2022","journal-title":"Front Med (Lausanne)"},{"key":"B84","doi-asserted-by":"publisher","DOI":"10.1002\/pon.4872","article-title":"Existential distress in cancer: Alleviating suffering from fundamental loss and change","volume":"27","author":"Vehling","year":"2018","journal-title":"Psychooncology"},{"key":"B85","doi-asserted-by":"publisher","DOI":"10.1007\/BF03401308","article-title":"Results of the Thyroid Cancer Alliance international patient\/survivor survey: Psychosocial\/informational support needs, treatment side effects and international differences in care","volume":"12","author":"Banach","year":"2013","journal-title":"Hormones (Athens)"},{"key":"B86","doi-asserted-by":"publisher","DOI":"10.1007\/s12020-021-02786-y","article-title":"Distress, anxiety, depression and unmet needs in thyroid cancer survivors: a longitudinal study","volume":"74","author":"Dionisi-Vici","year":"2021","journal-title":"Endocrine"}],"container-title":["Frontiers in Endocrinology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fendo.2025.1392283\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T05:29:49Z","timestamp":1759210189000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fendo.2025.1392283\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9,30]]},"references-count":86,"alternative-id":["10.3389\/fendo.2025.1392283"],"URL":"https:\/\/doi.org\/10.3389\/fendo.2025.1392283","relation":{},"ISSN":["1664-2392"],"issn-type":[{"value":"1664-2392","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,9,30]]},"article-number":"1392283"}}