{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T04:13:11Z","timestamp":1787026391231,"version":"build-2736575974"},"reference-count":58,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T00:00:00Z","timestamp":1762128000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Endocrinol."],"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study investigates the relationship between a new anthropometric measure, the Body Shape Index (ABSI), and body composition and biochemical parameters in hemodialysis patients and, for the first time, the correlation between ABSI and muscle strength and function in these patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      A cross-sectional study was conducted on a sample of 80 patients who were regularly treated in the hemodialysis unit of a single medical center of the University Hospital of Ljubljana, Slovenia. General anthropometric parameters body mass index (BMI) and ABSI=(WC\/(BMI\n                      <jats:sup>2\/3<\/jats:sup>\n                      x height\u00bd) as well as body composition data (fat mass FM, fat-free mass FFM, fat-free mass index FFMI, skeletal muscle index SMI) were determined in 25 women (aged 74.5 \u00b1 7.5 years) and 55 men (aged 70.1 \u00b1 6.6 years) with overweight (25 kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      \u2264 BMI &amp;lt; 30 kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      ) and obesity (BMI \u2265 30 kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      ) by bioelectrical impedance analysis (BIA). Muscle strength was determined using a hand grip strength test, while muscle performance was assessed using the sit-to-stand test.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      ABSI was significantly negatively associated with muscle strength, functional tests and SMI only in men. Based on the median ABSI value (0.090273 m\n                      <jats:sup>11\/6<\/jats:sup>\n                      \u00b7kg\n                      <jats:sup>\u22122\/3<\/jats:sup>\n                      in women and 0.090893 m\n                      <jats:sup>11\/6<\/jats:sup>\n                      \u00b7kg\n                      <jats:sup>\u22122\/3<\/jats:sup>\n                      in men), women with a higher ABSI had a significantly higher glucose concentration than those with a lower ABSI. Men with a lower ABSI obtained significantly better results in the hand grip test, sit-to-stand test and waist circumference (WC).\n                    <\/jats:p>\n                    <jats:p>In conclusion, our findings suggest an inverse association between ABSI and muscle strength and function in male hemodialysis patients, indicating that higher ABSI may reflect poorer physical condition in this population. Further longitudinal studies are needed to explore the clinical significance of this relationship.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fendo.2025.1585193","type":"journal-article","created":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T05:21:32Z","timestamp":1762147292000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["The usefulness of a body shape index in assessing muscle function and strength in older adults hemodialysis patients"],"prefix":"10.3389","volume":"16","author":[{"given":"Bojan","family":"Knap","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo\u0161tjan","family":"\u017dvanut","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucija","family":"Brezo\u010dnik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mihaela","family":"Jurdana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2025,11,3]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2019.01.001","article-title":"US renal data system 2018 annual data report: epidemiology of kidney disease in the United States","volume":"73","author":"Saran","year":"2019","journal-title":"Am J Kidney Dis"},{"key":"B2","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1016\/j.krcp.2014.04.001","article-title":"Excess mortality among patients on dialysis: Comparison with the general population in Korea","volume":"33","author":"Choi","year":"2014","journal-title":"Kidney Res Clin Pract"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1038\/oby.2008.664","article-title":"Comparison of overall obesity and body fat distribution in predicting risk of mortality","volume":"17","author":"Reis","year":"2009","journal-title":"Obesity"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1038\/oby.2009.44","article-title":"Clinical utility of waist circumference in predicting all-cause mortality in a preventive cardiology clinic population: a PreCIS Database Study","volume":"17","author":"Bajaj","year":"2009","journal-title":"Obes Silver Spring Md"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1104119","article-title":"General and abdominal obesity and risk of death among black women","volume":"365","author":"Boggs","year":"2011","journal-title":"N Engl J Med"},{"key":"B6","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1007\/s00394-011-0286-0","article-title":"Waist-to-height ratio, waist circumference, and body mass index as indices of cardiometabolic risk among 36,642 Taiwanese adults","volume":"52","author":"Li","year":"2013","journal-title":"Eur J Nutr"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfp168","article-title":"Is there any survival advantage of obesity in Southern European hemodialysis patients","volume":"24","author":"Chazot","year":"2009","journal-title":"Nephrol Dial Transplant Off Publ Eur Dial Transpl Assoc - Eur Ren Assoc"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2008.12.040","article-title":"Abdominal obesity and all-cause and cardiovascular mortality in end-stage renal disease","volume":"53","author":"Postorino","year":"2009","journal-title":"J Am Coll Cardiol"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1038\/ki.2009.524","article-title":"Both low muscle mass and low fat are associated with higher all-cause mortality in hemodialysis patients","volume":"77","author":"Huang","year":"2010","journal-title":"Kidney Int"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1053\/j.jrn.2011.11.002","article-title":"Malnutrition (subjective global assessment) scores and serum albumin levels, but not body mass index values, at initiation of dialysis are independent predictors of mortality: a 10-year clinical cohort study","volume":"22","author":"Chan","year":"2012","journal-title":"J Ren Nutr Off J Counc Ren Nutr Natl Kidney Found"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)30949-7","article-title":"BMI and mortality: the limits of epidemiological evidence","volume":"388","author":"Berrigan","year":"2016","journal-title":"Lancet Lond Engl"},{"key":"B12","article-title":"Chronic hemodialysis patients with visceral obesity have a higher risk for cardiovascular events","volume":"20","author":"Moriyama","year":"2011","journal-title":"Asia Pac J Clin Nutr"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfr057","article-title":"Abdominal obesity is the most significant metabolic syndrome component predictive of cardiovascular events in chronic hemodialysis patients","volume":"26","author":"Wu","year":"2011","journal-title":"Nephrol Dial Transplant Off Publ Eur Dial Transpl Assoc - Eur Ren Assoc"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1038\/s41366-021-01026-7","article-title":"Enhanced prediction of renal function decline by replacing waist circumference with \u201cA Body Shape Index (ABSI)\u201d in diagnosing metabolic syndrome: a retrospective cohort study in Japan","volume":"46","author":"Nagayama","year":"2022","journal-title":"Int J Obes"},{"key":"B15","doi-asserted-by":"publisher","first-page":"e39504","DOI":"10.1371\/journal.pone.0039504","article-title":"A new body shape index predicts mortality hazard independently of body mass index","volume":"7","author":"Krakauer","year":"2012","journal-title":"PloS One"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1007\/s11695-018-3117-z","article-title":"ABSI (A body shape index) and ARI (Anthropometric risk indicator) in bariatric surgery. First application on a bariatric cohort and possible clinical use","volume":"28","author":"Consalvo","year":"2018","journal-title":"Obes Surg"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1001711","article-title":"Observational studies: getting clear about transparency","volume":"11","year":"2014","journal-title":"PloS Med"},{"key":"B18","doi-asserted-by":"publisher","first-page":"14541","DOI":"10.1038\/s41598-020-71302-5","article-title":"A Body Shape Index (ABSI) achieves better mortality risk stratification than alternative indices of abdominal obesity: results from a large European cohort","volume":"10","author":"Christakoudi","year":"2020","journal-title":"Sci Rep"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1007\/s40519-019-00678-9","article-title":"Comparison of visceral, general and central obesity indices in the prediction of metabolic syndrome in maintenance hemodialysis patients","volume":"25","author":"Zhou","year":"2020","journal-title":"Eat Weight Disord - Stud Anorex Bulim Obes"},{"key":"B20","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1186\/s13098-018-0323-8","article-title":"Relationship between \u201ca body shape index (ABSI)\u201d and body composition in obese patients with type 2 diabetes","volume":"10","author":"Gomez-Peralta","year":"2018","journal-title":"Diabetol Metab Syndr"},{"key":"B21","doi-asserted-by":"publisher","first-page":"300","DOI":"10.1016\/j.jamda.2019.12.012","article-title":"Asian working group for sarcopenia: 2019 consensus update on sarcopenia diagnosis and treatment","volume":"21","author":"Chen","year":"2020","journal-title":"J Am Med Dir Assoc"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph17186797","article-title":"Association of body shape index (ABSI) with hand grip strength","volume":"17","author":"Krakauer","year":"2020","journal-title":"Int J Environ Res Public Health"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamda.2014.11.013","article-title":"Defining sarcopenia in terms of incident adverse outcomes","volume":"16","author":"Woo","year":"2015","journal-title":"J Am Med Dir Assoc"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1177\/2050312120910358","article-title":"What are the association patterns between handgrip strength and adverse health conditions? A topical review","volume":"8","author":"McGrath","year":"2020","journal-title":"SAGE Open Med"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.3389\/fpubh.2023.1087248","article-title":"Physical performance and muscle strength rather than muscle mass are predictor of all-cause mortality in hemodialysis patients","volume":"11","author":"Chen","year":"2023","journal-title":"Front Public Health"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/61.10.1059","article-title":"The loss of skeletal muscle strength, mass, and quality in older adults: the health, aging and body composition study","volume":"61","author":"Goodpaster","year":"2006","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/56.5.b209","article-title":"Longitudinal muscle strength changes in older adults: influence of muscle mass, physical activity, and health","volume":"56","author":"Hughes","year":"2001","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"B28","doi-asserted-by":"publisher","first-page":"601","DOI":"10.1186\/s12889-018-5538-y","article-title":"Validation of the NPAQ-short \u2013 a brief questionnaire to monitor physical activity and compliance with the WHO recommendations","volume":"18","author":"Danquah","year":"2018","journal-title":"BMC Public Health"},{"key":"B29","doi-asserted-by":"publisher","first-page":"583","DOI":"10.1016\/j.clnu.2012.06.010","article-title":"Sarcopenic obesity: A Critical appraisal of the current evidence","volume":"31","author":"Prado","year":"2012","journal-title":"Clin Nutr Edinb Scotl"},{"key":"B30","doi-asserted-by":"publisher","first-page":"45","DOI":"10.4103\/jrms.jrms_590_21","article-title":"Atherogenic index of plasma: A valuable novel index to distinguish patients with unstable atherogenic plaques","volume":"27","author":"Khosravi","year":"2022","journal-title":"J Res Med Sci"},{"key":"B31","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0050573","article-title":"Could the new body shape index predict the new onset of diabetes mellitus in the Chinese population","volume":"8","author":"He","year":"2013","journal-title":"PloS One"},{"key":"B32","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2014.03.015","article-title":"Inverse relationship between \u201ca body shape index\u201d (ABSI) and fat-free mass in women and men: Insights into mechanisms of sarcopenic obesity","volume":"34","author":"Biolo","year":"2015","journal-title":"Clin Nutr Edinb Scotl"},{"key":"B33","doi-asserted-by":"publisher","first-page":"31776","DOI":"10.1038\/s41598-024-82751-7","article-title":"Correlation and predictive value of novel anthropometric indicators with adult sarcopenia and sarcopenia obesity","volume":"14","author":"Wu","year":"2024","journal-title":"Sci Rep"},{"key":"B34","doi-asserted-by":"publisher","first-page":"637","DOI":"10.1186\/s12877-025-06310-z","article-title":"Predictive efficacy of waist-related indices for sarcopenic obesity incidence in Chinese older adults: a nationwide cohort study","volume":"25","author":"Zhang","year":"2025","journal-title":"BMC Geriatr"},{"key":"B35","doi-asserted-by":"publisher","DOI":"10.1111\/obr.12666","article-title":"Effectiveness of A Body Shape Index (ABSI) in predicting chronic diseases and mortality: a systematic review and meta-analysis","volume":"19","author":"Ji","year":"2018","journal-title":"Obes Rev Off J Int Assoc Study Obes"},{"key":"B36","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0269956","article-title":"Identification of sarcopenic obesity in adults undergoing orthopaedic surgery: Relationship between \u201ca body shape index\u201d (ABSI) and fat-free mass. A cross -sectional study","volume":"17","author":"Toma\u017ei\u010d","year":"2022","journal-title":"PloS One"},{"key":"B37","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2022.839074","article-title":"Association of sarcopenia and a body shape index with overall and cause-specific mortality","volume":"13","author":"Qiao","year":"2022","journal-title":"Front Endocrinol (Lausanne)"},{"key":"B38","doi-asserted-by":"publisher","DOI":"10.3389\/fnut.2024.1305330","article-title":"The predictive ability of ABSI compared to BMI for mortality and frailty among older adults","volume":"11","author":"Shafran","year":"2024","journal-title":"Front Nutr"},{"key":"B39","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1007\/s11357-015-9860-3","article-title":"Sex-specific differences in risk factors for sarcopenia amongst community-dwelling older adults","volume":"37","author":"Tay","year":"2015","journal-title":"AGE"},{"key":"B40","doi-asserted-by":"publisher","DOI":"10.1016\/j.archger.2017.11.008","article-title":"Association of nutrition and immune-endocrine dysfunction with muscle mass and performance in cognitively impaired older adults","volume":"75","author":"Tay","year":"2018","journal-title":"Arch Gerontol Geriatr"},{"key":"B41","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbmt.2021.02.020","article-title":"The reliability and validity of the 30-seconds sit-to-stand test and its capacity for assessment of the functional status of hemodialysis patients","volume":"27","author":"Figueiredo","year":"2021","journal-title":"J Bodyw Mov Ther"},{"key":"B42","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.10261013","article-title":"Comparative associations of muscle mass and muscle strength with mortality in dialysis patients","volume":"9","author":"Isoyama","year":"2014","journal-title":"Clin J Am Soc Nephrol CJASN"},{"key":"B43","doi-asserted-by":"publisher","DOI":"10.1016\/j.kint.2017.01.024","article-title":"Sarcopenia and its individual criteria are associated, in part, with mortality among patients on hemodialysis","volume":"92","author":"Kittiskulnam","year":"2017","journal-title":"Kidney Int"},{"key":"B44","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0211988","article-title":"The associations of fat tissue and muscle mass indices with all-cause mortality in patients undergoing hemodialysis","volume":"14","author":"Yajima","year":"2019","journal-title":"PloS One"},{"key":"B45","doi-asserted-by":"publisher","DOI":"10.1038\/ejcn.2016.186","article-title":"Lower thigh muscle mass is associated with all-cause and cardiovascular mortality in elderly hemodialysis patients","volume":"71","author":"Fukasawa","year":"2017","journal-title":"Eur J Clin Nutr"},{"key":"B46","doi-asserted-by":"publisher","DOI":"10.3390\/jfmk3040053","article-title":"The influence of upper and lower extremity strength on performance-based sarcopenia assessment tests","volume":"3","author":"Harris-Love","year":"2018","journal-title":"J Funct Morphol Kinesiol"},{"key":"B47","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/gly206","article-title":"Frailty among patients receiving hemodialysis: evolution of components and associations with mortality","volume":"74","author":"Johansen","year":"2019","journal-title":"J Gerontol Ser A"},{"key":"B48","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1093\/ageing\/afy169","article-title":"Sarcopenia: revised European consensus on definition and diagnosis","volume":"48","author":"Cruz-Jentoft","year":"2019","journal-title":"Age Ageing"},{"key":"B49","doi-asserted-by":"publisher","DOI":"10.1016\/j.numecd.2007.10.002","article-title":"Sarcopenic obesity: a new category of obesity in the elderly","volume":"18","author":"Zamboni","year":"2008","journal-title":"Nutr Metab Cardiovasc Dis NMCD"},{"key":"B50","doi-asserted-by":"publisher","DOI":"10.1001\/jama.299.11.1259","article-title":"Metabolic responses to reduced daily steps in healthy nonexercising men","volume":"299","author":"Olsen","year":"2008","journal-title":"JAMA"},{"key":"B51","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2023.03.016","article-title":"Bioimpedance phase angle is independently associated with myosteatosis: The Shizuoka study","volume":"42","author":"Kato","year":"2023","journal-title":"Clin Nutr"},{"key":"B52","doi-asserted-by":"publisher","first-page":"297","DOI":"10.1016\/j.nut.2013.08.017","article-title":"Longitudinal changes in bioimpedance phase angle reflect inverse changes in serum IL-6 levels in maintenance hemodialysis patients","volume":"30","author":"Beberashvili","year":"2014","journal-title":"Nutr Burbank Los Angel Cty Calif"},{"key":"B53","doi-asserted-by":"publisher","DOI":"10.3389\/fnut.2021.742081","article-title":"Association between phase angle and sarcopenia in patients undergoing peritoneal dialysis","volume":"8","author":"Do","year":"2021","journal-title":"Front Nutr"},{"key":"B54","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.2001.90.4.1334","article-title":"Relationship between fat-to-fat-free mass ratio and decrements in leg strength after downhill running","volume":"90","author":"Hickner","year":"2001","journal-title":"J Appl Physiol"},{"key":"B55","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2021.07.035","article-title":"Bioelectrical impedance (BIA)-derived phase angle in adults with obesity: A systematic review","volume":"40","author":"Di Vincenzo","year":"2021","journal-title":"Clin Nutr"},{"key":"B56","doi-asserted-by":"publisher","first-page":"e12569","DOI":"10.1002\/rmb2.12569","article-title":"The roles of sex hormones in the pathophysiology of age-related sarcopenia and frailty","volume":"23","author":"Hosoi","year":"2024","journal-title":"Reprod Med Biol"},{"key":"B57","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2021.682012","article-title":"Sarcopenia and menopause: the role of estradiol","volume":"12","author":"Geraci","year":"2021","journal-title":"Front Endocrinol (Lausanne)"},{"key":"B58","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2014.00217","article-title":"Sarcopenia and androgens: a link between pathology and treatment","volume":"5","author":"Basualto-Alarc\u00f3n","year":"2014","journal-title":"Front Endocrinol (Lausanne)"}],"container-title":["Frontiers in Endocrinology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fendo.2025.1585193\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T05:21:33Z","timestamp":1762147293000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fendo.2025.1585193\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,3]]},"references-count":58,"alternative-id":["10.3389\/fendo.2025.1585193"],"URL":"https:\/\/doi.org\/10.3389\/fendo.2025.1585193","relation":{},"ISSN":["1664-2392"],"issn-type":[{"value":"1664-2392","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11,3]]},"article-number":"1585193"}}