{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T20:58:46Z","timestamp":1785531526588,"version":"3.56.0"},"reference-count":8,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,7,31]],"date-time":"2025-07-31T00:00:00Z","timestamp":1753920000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Endocrinol."],"abstract":"<jats:p>Recent advances in automated insulin delivery (AID) system have been remarkable. The advanced hybrid closed-loop (AHCL) system made it easier to achieve optimal glycemic targets. According to previous studies, the AHCL system achieves relatively good glycemic control without strict carbohydrate input. These studies suggested that AID systems potentially improve glycemic control among patients with difficulty with self-management. However, few studies have focused on the efficacy of the systems among these patients. We present a case of a 30-year-old woman with type 1 diabetes and intellectual disabilities (full-scale intelligence quotient = 67) due to Shwachman-Diamond syndrome. While using a sensor-augmented pump with the predictive low glucose suspend system, her glycated hemoglobin levels consistently ranged from 9.0% to 10.0%, and she experienced frequent hospitalizations due to diabetic ketoacidosis. Stepping up to a hybrid closed-loop system achieved better glycemic control and prevented hospitalizations due to diabetic ketoacidosis. Finally, the patient achieved optimal glycemic control through the use of the AHCL system. Our case highlights the potential of AID systems in patients with type 1 diabetes and self-management difficulties, including those with intellectual disabilities.<\/jats:p>","DOI":"10.3389\/fendo.2025.1611540","type":"journal-article","created":{"date-parts":[[2025,7,31]],"date-time":"2025-07-31T04:10:29Z","timestamp":1753935029000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["Efficacy of an advanced hybrid closed-loop system in a patient with type 1 diabetes and intellectual disability: a case report"],"prefix":"10.3389","volume":"16","author":[{"given":"Hidetsugu","family":"Taka","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keiji","family":"Sugai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jumpei","family":"Shikuma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryo","family":"Suzuki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2025,7,31]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1089\/dia.2023.0433","article-title":"Celebrating the data from 100,000 real-world users of the miniMed 780G system in Europe, Middle East, and Africa collected over 3 years: from data to clinical evidence","volume":"26","author":"Choudhary","year":"2024","journal-title":"Diabetes Technol Ther"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1007\/s13300-023-01427-z","article-title":"Real-world user and clinician perspective and experience with miniMed 780G advanced hybrid closed loop system","volume":"14","author":"Kesavadev","year":"2023","journal-title":"Diabetes Ther"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.2337\/dc22-1692","article-title":"Simplified meal announcement versus precise carbohydrate counting in adolescents with type 1 diabetes using the miniMed 780G advanced hybrid closed loop system: A randomized controlled trial comparing glucose control","volume":"46","author":"Petrovski","year":"2023","journal-title":"Diabetes Care"},{"key":"B4","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1089\/dia.2023.0429","article-title":"Twelve-month follow-up from a randomized controlled trial of simplified meal announcement versus precise carbohydrate counting in adolescents with type 1 diabetes using the miniMed 780G advanced hybrid closed-loop system","volume":"26","author":"Petrovski","year":"2024","journal-title":"Diabetes Technol Ther"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1089\/dia.2023.0139","article-title":"Unannounced meal challenges using an advanced hybrid closed-loop system","volume":"25","author":"Shalit","year":"2023","journal-title":"Diabetes Technol Ther"},{"key":"B6","doi-asserted-by":"publisher","first-page":"503","DOI":"10.1186\/s12887-023-04324-3","article-title":"Clinical features, epidemiology, and treatment of Shwachman-Diamond syndrome: a systematic review","volume":"23","author":"Han","year":"2023","journal-title":"BMC Pediatr"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1055\/s-0031-1275699","article-title":"Shwachman-Diamond syndrome and type 1 diabetes mellitus: more than a chance association","volume":"119","author":"Gana","year":"2011","journal-title":"Exp Clin Endocrinol Diabetes"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1177\/17446295211032767","article-title":"Health\u00a0promotion challenges for young adults living with intellectual disability and\u00a0type 1 diabetes","volume":"26","author":"Marks","year":"2022","journal-title":"J Intellect Disabil"}],"container-title":["Frontiers in Endocrinology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fendo.2025.1611540\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,31]],"date-time":"2025-07-31T04:10:30Z","timestamp":1753935030000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fendo.2025.1611540\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,31]]},"references-count":8,"alternative-id":["10.3389\/fendo.2025.1611540"],"URL":"https:\/\/doi.org\/10.3389\/fendo.2025.1611540","relation":{},"ISSN":["1664-2392"],"issn-type":[{"value":"1664-2392","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7,31]]},"article-number":"1611540"}}