{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T09:58:47Z","timestamp":1787738327562,"version":"build-2784847793"},"reference-count":27,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,7,4]],"date-time":"2025-07-04T00:00:00Z","timestamp":1751587200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Endocrinol."],"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Diabetic foot ulcers (DFUs), a common complication of diabetes, are often accompanied by delayed wound healing, pain, psychological distress, and sleep disturbances.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>To evaluate the effectiveness of personalized continuous care (PCC) compared to routine care in improving wound healing, symptom severity, and psychological\/sleep outcomes in DFU patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective cohort study of 60 DFU patients (2021\u20132024) compared PCC (n=30) with routine care (n=30). Outcomes assessed included wound area reduction, granulation tissue coverage, symptom scores (ulceration, necrosis, pain), and validated psychological (SDS, SAS) and sleep (AIS) scales.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The PCC group showed superior wound healing (40.51% <jats:italic>vs<\/jats:italic>. 27.43% area reduction; 61.66% <jats:italic>vs<\/jats:italic>. 46.32% granulation coverage, p&amp;lt;0.05), lower symptom scores (ulceration: 3.18 \u00b1 0.45 <jats:italic>vs<\/jats:italic>. 4.46 \u00b1 0.6; pain: 2.01 \u00b1 0.29 <jats:italic>vs<\/jats:italic>. 3.45 \u00b1 0.58, p&amp;lt;0.01), and improved psychological (SDS: 32.1 \u00b1 3.88 <jats:italic>vs<\/jats:italic>. 44.87 \u00b1 4.05; SAS: 30.36 \u00b1 3.77 <jats:italic>vs<\/jats:italic>. 43.25 \u00b1 4.56, p&amp;lt;0.001) and sleep outcomes (AIS: 8.23 \u00b1 0.6 <jats:italic>vs<\/jats:italic>. 11.33 \u00b1 0.94, p&amp;lt;0.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>PCC enhances DFU wound healing, alleviates symptoms, and improves psychological well-being and sleep quality, supporting its integration routine clinical practice.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fendo.2025.1612047","type":"journal-article","created":{"date-parts":[[2025,7,4]],"date-time":"2025-07-04T04:10:52Z","timestamp":1751602252000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":4,"title":["Effectiveness of personalized continuous care in wound care of patients with diabetic foot 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