{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,24]],"date-time":"2026-02-24T11:00:25Z","timestamp":1771930825375,"version":"3.50.1"},"reference-count":44,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,2,6]],"date-time":"2026-02-06T00:00:00Z","timestamp":1770336000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100022963","name":"Key Research and Development Program of Zhejiang Province","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100022963","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002855","name":"Ministry of Science and Technology of the People's Republic of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002855","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Endocrinol."],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The global prevalence of type 2 diabetes mellitus (T2DM) has risen significantly since 1990, contributing substantially to mortality and posing a major public health challenge. While overweight\/obesity and insulin resistance, commonly reflected by the triglyceride-glucose (TyG) index, are established risk factors for the development of T2DM, their individual and combined effects on mortality among patients with T2DM remain incompletely elucidated. This study aimed to evaluate the associations between body mass index (BMI) and the TyG index with all-cause and cardiovascular disease (CVD) mortality in a large clinical cohort of type 2 diabetes mellitus (T2DM) patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      This retrospective cohort study included 15,796 T2DM adults (aged &amp;gt;18 years) from two hospitals in China (2010-2023). The primary outcome was all-cause mortality, with a mean follow-up duration of 2.8 years. BMI was categorized as normal weight (18.5-24.9 kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      ), overweight (25-29.9 kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      ), and obesity (\u226530 kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      ). The TyG index was calculated as ln [fasting triglycerides (mg\/dL) \u00d7 fasting glucose (mg\/dL)\/2]. Multiple Cox proportional hazards models were used to estimate adjusted hazard ratios (aHRs) and 95% confidence intervals (CIs) for mortality.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among 15,796 participants, 1,665 deaths were recorded, including 629 CVD-related deaths. Overweight and obesity were associated with lower all-cause mortality risk (aHR: 0.73, 95% CI: 0.65\u22120.81 and aHR: 0.86, 95% CI: 0.74\u22121.00, respectively). Higher TyG index quartiles (Q3 and Q4) were associated with decreased mortality risk (aHR: 0.85, 95% CI: 0.74\u22120.98; aHR: 0.84, 95% CI: 0.72\u22120.97). The protective effect of a higher BMI was more pronounced in patients aged 60 years or older.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Our findings revealed that BMI and the TyG index are associated with mortality risk in T2DM patients, particularly in older patients. However, these findings are observational and do not imply causality or validate prognostic use. Further studies using causal inference methods are necessary to inform clinical guidelines.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fendo.2026.1652682","type":"journal-article","created":{"date-parts":[[2026,2,6]],"date-time":"2026-02-06T12:47:20Z","timestamp":1770382040000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Individual and joint effects of overweight\/obesity and the triglyceride\u2212glucose index on mortality risk in type 2 diabetic patients: a retrospective cohort study in China"],"prefix":"10.3389","volume":"17","author":[{"given":"Anthony","family":"Diwon","sequence":"first","affiliation":[{"name":"Department of Epidemiology & Biostatistics, School of Public Health, Wenzhou Medical University","place":["Wenzhou, Zhejiang, China"]},{"name":"Department of Endocrinology, The Second Affiliated Hospital, Wenzhou Medical University","place":["Wenzhou, Zhejiang, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuxin","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Epidemiology & Biostatistics, School of Public Health, Wenzhou Medical University","place":["Wenzhou, Zhejiang, China"]},{"name":"Department of Endocrinology, The Second Affiliated Hospital, Wenzhou Medical University","place":["Wenzhou, Zhejiang, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yang","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Epidemiology & Biostatistics, School of Public Health, Wenzhou Medical University","place":["Wenzhou, Zhejiang, China"]},{"name":"Department of Endocrinology, The Second Affiliated Hospital, Wenzhou Medical University","place":["Wenzhou, Zhejiang, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xinlv","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Epidemiology & Biostatistics, School of Public Health, Wenzhou Medical University","place":["Wenzhou, Zhejiang, China"]},{"name":"Department of Endocrinology, The Second Affiliated Hospital, Wenzhou Medical University","place":["Wenzhou, Zhejiang, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hui","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Epidemiology & Biostatistics, School of Public Health, Wenzhou Medical University","place":["Wenzhou, Zhejiang, China"]},{"name":"Department of Endocrinology, The Second Affiliated Hospital, Wenzhou Medical University","place":["Wenzhou, Zhejiang, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ziyi","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Epidemiology & Biostatistics, School of Public Health, Wenzhou Medical University","place":["Wenzhou, Zhejiang, China"]},{"name":"Department of Endocrinology, The Second Affiliated Hospital, Wenzhou Medical University","place":["Wenzhou, Zhejiang, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guomiao","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Epidemiology & Biostatistics, School of Public Health, Wenzhou Medical University","place":["Wenzhou, Zhejiang, China"]},{"name":"Department of Endocrinology, The Second Affiliated Hospital, Wenzhou Medical University","place":["Wenzhou, Zhejiang, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qichao","family":"Sheng","sequence":"additional","affiliation":[{"name":"Department of Epidemiology & Biostatistics, School of Public Health, Wenzhou Medical University","place":["Wenzhou, Zhejiang, China"]},{"name":"Department of Endocrinology, The Second Affiliated Hospital, Wenzhou Medical University","place":["Wenzhou, Zhejiang, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huiqin","family":"Mei","sequence":"additional","affiliation":[{"name":"Department of Epidemiology & Biostatistics, School of Public Health, Wenzhou Medical University","place":["Wenzhou, Zhejiang, China"]},{"name":"Department of Endocrinology, The Second Affiliated Hospital, Wenzhou Medical University","place":["Wenzhou, Zhejiang, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yixi","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Epidemiology & Biostatistics, School of Public Health, Wenzhou Medical University","place":["Wenzhou, Zhejiang, China"]},{"name":"Department of Endocrinology, The Second Affiliated Hospital, Wenzhou Medical University","place":["Wenzhou, Zhejiang, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qingyang","family":"Mao","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, The Second Affiliated Hospital, Wenzhou Medical University","place":["Wenzhou, Zhejiang, China"]},{"name":"State Key Laboratory of Cognitive Intelligence, University of Science and Technology of China","place":["Hefei, Anhui, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chao","family":"Zheng","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, The Second Affiliated Hospital, Wenzhou Medical University","place":["Wenzhou, Zhejiang, China"]},{"name":"Department of Endocrinology, The Second Affiliated Hospital, School of Medicine, Zhejiang University","place":["Hangzhou, Zhejiang, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoyu","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Epidemiology & Biostatistics, School of Public Health, Wenzhou Medical University","place":["Wenzhou, Zhejiang, China"]},{"name":"Department of Endocrinology, The Second Affiliated Hospital, Wenzhou Medical University","place":["Wenzhou, Zhejiang, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guangyun","family":"Mao","sequence":"additional","affiliation":[{"name":"Department of Epidemiology & Biostatistics, School of Public Health, Wenzhou Medical University","place":["Wenzhou, Zhejiang, China"]},{"name":"Department of Endocrinology, The Second Affiliated Hospital, Wenzhou Medical University","place":["Wenzhou, Zhejiang, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2026,2,6]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(23)01301-6","article-title":"Global, regional, and national burden of diabetes from 1990 to 2021, with projections of prevalence to 2050: a systematic analysis for the Global Burden of Disease Study 2021","volume":"402","year":"2023","journal-title":"Lancet"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)31679-8","article-title":"Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015","volume":"388","year":"2016","journal-title":"Lancet"},{"key":"B3","volume-title":"Federation ID. IDF Diabetes Atlas, 10th edn","author":"Atlas","year":"2021"},{"key":"B4","doi-asserted-by":"publisher","first-page":"88","DOI":"10.1038\/nrendo.2017.151","article-title":"Global aetiology and epidemiology of type 2 diabetes mellitus and its complications","volume":"14","author":"Zheng","year":"2018","journal-title":"Nat Rev Endocrinol"},{"key":"B5","doi-asserted-by":"publisher","first-page":"398","DOI":"10.1016\/j.ihj.2022.07.008","article-title":"Association of country economy and socioeconomic factors on risk factor control for primary prevention of cardiovascular disease in patients with diabetes mellitus: Insights from the DISCOVER study","volume":"74","author":"Malik","year":"2022","journal-title":"Indian Heart J"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.2991\/jegh.k.191028.001","article-title":"Epidemiology of type 2 diabetes - global burden of disease and forecasted trends","volume":"10","author":"Khan","year":"2020","journal-title":"J Epidemiol Glob Health"},{"key":"B7","doi-asserted-by":"publisher","first-page":"e192696","DOI":"10.1001\/jamanetworkopen.2019.2696","article-title":"Association of diabetes with all-cause and cause-specific mortality in Asia: A pooled analysis of more than 1 million participants","volume":"2","author":"Yang","year":"2019","journal-title":"JAMA Netw Open"},{"key":"B8","unstructured":"Zhang\n              W\n            \n          \n          China\u2019s number of diabetes-related death in 2021"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.2337\/dc09-S062","article-title":"Diagnosis and classification of diabetes mellitus","year":"2009","journal-title":"Diabetes Care"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1016\/S2666-7568(22)00247-1","article-title":"Association of the triglyceride glucose index as a measure of insulin resistance with mortality and cardiovascular disease in populations from five continents (PURE study): a prospective cohort study","volume":"4","author":"Lopez-Jaramillo","year":"2023","journal-title":"Lancet Healthy Longev"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.3390\/jpm13030495","article-title":"The U-shape relationship between triglyceride-glucose index and the risk of diabetic retinopathy among the US population","volume":"13","author":"Zhou","year":"2023","journal-title":"J Pers Med"},{"key":"B12","doi-asserted-by":"publisher","first-page":"2","DOI":"10.2174\/1573399810666140214093600","article-title":"Assessment of pancreatic \u03b2-cell function: review of methods and clinical applications","volume":"10","author":"Cersosimo","year":"2014","journal-title":"Curr Diabetes Rev"},{"key":"B13","doi-asserted-by":"publisher","first-page":"101941","DOI":"10.1016\/j.pmedr.2022.101941","article-title":"Triglyceride glucose index: A new biomarker in predicting cardiovascular risk","volume":"29","author":"Ara\u00fajo","year":"2022","journal-title":"Prev Med Rep"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.2147\/DMSO.S343374","article-title":"Association between triglyceride-glucose index and 2-year adverse cardiovascular and cerebrovascular events in patients with type 2 diabetes mellitus who underwent off-pump coronary artery bypass grafting","volume":"15","author":"Chen","year":"2022","journal-title":"Diabetes Metab Syndr Obes"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-150-9-200905050-00006","article-title":"A new equation to estimate glomerular filtration rate","volume":"150","author":"Levey","year":"2009","journal-title":"Ann Intern Med"},{"key":"B16","unstructured":"Optimal BMI cutoff points in obesity screening for Chinese\n          \n          \n            \n              Wang\n              Z\n            \n          \n          \n          2022"},{"key":"B17","unstructured":"Obesity and overweight\n          \n          \n            \n              Organization\n              WH\n            \n          \n          \n          2024"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.2147\/COPD.S141295","article-title":"Comparison of World Health Organization and Asia-Pacific body mass index classifications in COPD patients","volume":"12","author":"Lim","year":"2017","journal-title":"Int J Chron Obstruct Pulmon Dis"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.26574\/maedica.2021.16.3.375","article-title":"Association of triglyceride-glucose index (TyG index) with HbA1c and insulin resistance in type 2 diabetes mellitus","volume":"16","author":"Selvi","year":"2021","journal-title":"Maedica (Bucur)"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.18869\/acadpub.jcbr.1.1.11","article-title":"Triglyceride-glucose index simulation","volume":"1","author":"Hosseini","year":"2017","journal-title":"J Clin Basic Res"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1038\/oby.2007.217","article-title":"Morbidity and mortality risk associated with an overweight BMI in older men and women","volume":"15","author":"Janssen","year":"2007","journal-title":"Obesity"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2012.09.004","article-title":"Obesity paradox: differential effects on cancer and noncancer mortality in patients with type 2 diabetes mellitus","volume":"226","author":"Tseng","year":"2013","journal-title":"Atherosclerosis"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1990.00390170095021","article-title":"Body weight as a risk factor in the elderly","volume":"150","author":"Tayback","year":"1990","journal-title":"Arch Internal Med"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwu052","article-title":"Overweight in early adulthood, adult weight change, and risk of type 2 diabetes, cardiovascular diseases, and certain cancers in men: a cohort study","volume":"179","author":"de Mutsert","year":"2014","journal-title":"Am J Epidemiol"},{"key":"B25","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12916-017-0978-2","article-title":"The extra cost of comorbidity: multiple illnesses and the economic burden of non-communicable diseases","volume":"15","author":"Cortaredona","year":"2017","journal-title":"BMC Med"},{"key":"B26","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1186\/s12944-024-02060-w","article-title":"Relative importance of triglyceride glucose index combined with body mass index in predicting recovery from prediabetic state to normal fasting glucose: a cohort analysis based on a Chinese physical examination population","volume":"23","author":"Yang","year":"2024","journal-title":"Lipids Health Dis"},{"key":"B27","doi-asserted-by":"publisher","first-page":"108","DOI":"10.1186\/s12933-020-01086-5","article-title":"Impacts of triglyceride-glucose index on prognosis of patients with type 2 diabetes mellitus and non-ST-segment elevation acute coronary syndrome: results from an observational cohort study in China","volume":"19","author":"Zhao","year":"2020","journal-title":"Cardiovasc Diabetol"},{"key":"B28","doi-asserted-by":"publisher","first-page":"74","DOI":"10.1186\/s13098-018-0376-8","article-title":"Metabolic clustering of risk factors: evaluation of Triglyceride-glucose index (TyG index) for evaluation of insulin resistance","volume":"10","author":"Khan","year":"2018","journal-title":"Diabetol Metab Syndr"},{"key":"B29","doi-asserted-by":"publisher","first-page":"e0212963","DOI":"10.1371\/journal.pone.0212963","article-title":"Comparison of triglyceride glucose index, and related parameters to predict insulin resistance in Korean adults: An analysis of the 2007\u20132010 Korean National Health and Nutrition Examination Survey","volume":"14","author":"Lim","year":"2019","journal-title":"PloS One"},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.1038\/s41574-021-00512-2","article-title":"Type 2 diabetes mellitus in older adults: clinical considerations and management","volume":"17","author":"Bellary","year":"2021","journal-title":"Nat Rev Endocrinol"},{"key":"B31","doi-asserted-by":"publisher","DOI":"10.3390\/jpm12111911","article-title":"Multimorbidity, frailty and diabetes in older people-identifying interrelationships and outcomes","volume":"12","author":"Sinclair","year":"2022","journal-title":"J Pers Med"},{"key":"B32","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2014.03.007","article-title":"Muscle contractile and metabolic dysfunction is a common feature of sarcopenia of aging and chronic diseases: from sarcopenic obesity to cachexia","volume":"33","author":"Biolo","year":"2014","journal-title":"Clin Nutr"},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00019.2005","article-title":"Nutrition and aging: changes in the regulation of energy metabolism with aging","volume":"86","author":"Roberts","year":"2006","journal-title":"Physiol Rev"},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.1080\/02640414.2011.553965","article-title":"Obesity paradoxes","volume":"29","author":"McAuley","year":"2011","journal-title":"J Sports Sci"},{"key":"B35","doi-asserted-by":"publisher","first-page":"e002260","DOI":"10.1136\/openhrt-2023-002260","article-title":"Obesity paradox: a myth or reality, time to reveal the fact in a South Asian cohort presenting with STE-ACS undergoing primary percutaneous coronary intervention","volume":"10","author":"Kumar","year":"2023","journal-title":"Open Heart"},{"key":"B36","doi-asserted-by":"publisher","DOI":"10.1038\/nrendo.2014.175","article-title":"Personalized weight loss strategies\u2014the role of macronutrient distribution","volume":"10","author":"Martinez","year":"2014","journal-title":"Nat Rev Endocrinol"},{"key":"B37","doi-asserted-by":"publisher","DOI":"10.1017\/S0029665113001316","article-title":"Dietary management of the metabolic syndrome - one size fits all","volume":"72","author":"Champagne","year":"2013","journal-title":"Proc Nutr Soc"},{"key":"B38","doi-asserted-by":"publisher","DOI":"10.3390\/nu15204314","article-title":"Dietary and nutritional guidelines for people with diabetes","volume":"15","author":"Iizuka","year":"2023","journal-title":"Nutrients"},{"key":"B39","doi-asserted-by":"publisher","DOI":"10.1111\/ijcp.12384","article-title":"The importance of weight management in type 2 diabetes mellitus","volume":"68","author":"Wilding","year":"2014","journal-title":"Int J Clin Pract"},{"key":"B40","doi-asserted-by":"publisher","DOI":"10.1097\/EDE.0b013e31828c776c","article-title":"The \u201cobesity paradox\u201d explained","volume":"24","author":"Banack","year":"2013","journal-title":"Epidemiology"},{"key":"B41","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1007\/s11912-016-0539-4","article-title":"The obesity paradox in cancer: a review","volume":"18","author":"Lennon","year":"2016","journal-title":"Curr Oncol Rep"},{"key":"B42","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1093\/aje\/kwq341","article-title":"Reverse causation and illness-related weight loss in observational studies of body weight and mortality","volume":"173","author":"Flegal","year":"2011","journal-title":"Am J Epidemiol"},{"key":"B43","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.109.192574","article-title":"Mortality, health outcomes, and body mass index in the overweight range: a science advisory from the American Heart Association","volume":"119","author":"Lewis","year":"2009","journal-title":"Circulation"},{"key":"B44","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199509143331102","article-title":"Association of weight loss and weight fluctuation with mortality among Japanese American men","volume":"333","author":"Iribarren","year":"1995","journal-title":"N Engl J Med"}],"container-title":["Frontiers in Endocrinology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fendo.2026.1652682\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,24]],"date-time":"2026-02-24T09:59:14Z","timestamp":1771927154000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fendo.2026.1652682\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,6]]},"references-count":44,"alternative-id":["10.3389\/fendo.2026.1652682"],"URL":"https:\/\/doi.org\/10.3389\/fendo.2026.1652682","relation":{},"ISSN":["1664-2392"],"issn-type":[{"value":"1664-2392","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,6]]},"article-number":"1652682"}}