{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T07:30:47Z","timestamp":1774510247509,"version":"3.50.1"},"reference-count":35,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T00:00:00Z","timestamp":1774483200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Endocrinol."],"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To describe the correlation between abdominal muscle mass and CAC in T2DM patients using DSCT, and to determine the preferred muscle imaging indicators in diagnosing and predicting positive CAC patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and methods<\/jats:title>\n                    <jats:p>\n                      108 T2DM patients were included (57.0 \u00b1 10.9 years old). We acquired both CAC score and abdominal-chest DSCT data. DSCT measurements (intermuscular adipose tissue [IMAT], total abdominal muscle area [TAMA], normal attenuation muscle area [NAMA], low attenuation muscle area [LAMA], fat fraction [FF], LAMA\/body mass index [BMI], NAMA\/BMI, and NAMA\/TAMA index) of 7 muscles (psoas major [PM], quadratus lumborum [QL], erector spinae [ES], rectus abdominis [RA], transversus abdominis [TA], oblique abdominals [OA], abdominal core muscles [ACM]) on the level of the third lumbar vertebra were conducted. T2DM patients were divided into four subgroups based on CAC score: negative controls (NCs) (0 score), mild (&amp;lt;100 score), moderate (100\u2013300 score), and severe (&amp;gt;300 score). The following statistical analyses were conducted: intergroup differences were compared using the Mann-Whitney test, diagnostic performance was evaluated via receiver operating characteristic (ROC) curve analysis, associations were assessed with Spearman correlation, and predictors were identified through logistic regression. A\n                      <jats:italic>P<\/jats:italic>\n                      -value &amp;lt;0.05 was considered statistically significant.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Result<\/jats:title>\n                    <jats:p>\n                      Compared with NCs, TAMA, NAMA, NAMA\/BMI, and NAMA\/TAMA index were significantly higher in the group of all CAC (\n                      <jats:italic>P<\/jats:italic>\n                      &amp;lt;0.05), while TAMA was significantly lower (\n                      <jats:italic>P<\/jats:italic>\n                      &amp;lt;0.05). The NAMA, NAMA\/BMI and the NAMA\/TAMA index in four representative muscles (PM, QL, ES, and RA) demonstrated certain diagnostic performance (AUC range, 0.70-0.97, 0.85-0.99 and 0.81-0.97). Overall, NAMA\/TAMA index in OA exhibited the strongest negative correlation with CAC score (r=-0.56,\n                      <jats:italic>P<\/jats:italic>\n                      &amp;lt; 0.01), and NAMA\/BMI in the ACM emerged as an independent risk factor for positive CAC (odds ratio=0.63,\n                      <jats:italic>P<\/jats:italic>\n                      = 0.02).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Abdominal muscle mass measured by DSCT was significantly associated with CAC score in T2DM patients. Overall, the NAMA\/BMI showed optimal diagnostic value for CAC across severity levels. Moreover, NAMA\/BMI in the ACM may serve as a predictive biomarker for positive CAC.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fendo.2026.1803735","type":"journal-article","created":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T05:29:16Z","timestamp":1774502956000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Association between abdominal muscle mass measured by dual-source computed tomography and coronary artery calcification in patients with Type 2 diabetes mellitus"],"prefix":"10.3389","volume":"17","author":[{"given":"Xiaolong","family":"Chen","sequence":"first","affiliation":[{"name":"Department of Radiology, The First Affiliated Hospital, Hengyang Medical School, University of South China","place":["Hengyang, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meidi","family":"Tan","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, The 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China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xihua","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Radiology, The First Affiliated Hospital, Hengyang Medical School, University of South China","place":["Hengyang, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wenxuan","family":"Lei","sequence":"additional","affiliation":[{"name":"Department of Radiology, The First Affiliated Hospital, Hengyang Medical School, University of South China","place":["Hengyang, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mingxuan","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Radiology, The First Affiliated Hospital, Hengyang Medical School, University of South China","place":["Hengyang, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fei","family":"Peng","sequence":"additional","affiliation":[{"name":"Department of Radiology, The First 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