{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T05:05:26Z","timestamp":1784264726488,"version":"3.55.0"},"reference-count":22,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T00:00:00Z","timestamp":1784246400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Endocrinol."],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      The relationship between endometrial thickness and adverse pregnancy outcomes has garnered significant attention from researchers. The aim of this study was to investigates whether endometrial thickness (EMT) is a risk factor for hypertensive disorders of pregnancy (HDP) in women undergoing\n                      <jats:italic>in vitro<\/jats:italic>\n                      fertilization (IVF) due to male-factor infertility.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This single center retrospective cohort study included 2,536 women aged 20\u201340 years with male-factor infertility who underwent their first frozen-thawed embryo transfer (FET) and had a singleton live birth. Endometrial thickness was measured via transvaginal ultrasound on the day of embryo transfer, and patients were divided into three groups: \u22648 mm, 8\u201314 mm, and \u226514 mm. The primary outcome was the incidence of HDP.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The overall HDP rate was 3.67%, with no significant difference across EMT groups: 3.97% in the \u2264 8\u00a0mm group, 3.74% in the 8\u201314 mm group, and 3.03% in the \u2265 14\u00a0mm group (p=0.760). Older maternal age and higher BMI were significant risk factors for HDP [maternal age (OR 1.10, 95% CI 1.05-1.16, p=0.000) and BMI \u2265 24.0 Kg\/m\u00b2 (OR 2.40, 95% CI 1.10-5.25, p=0.028)], while EMT was not associated with HDP risk.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Endometrial thickness was not a significant risk factor for HDP in women with male-factor infertility undergoing their first FET.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fendo.2026.1896764","type":"journal-article","created":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T04:23:12Z","timestamp":1784262192000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Endometrial thickness is not a risk factor for hypertensive disorders of pregnancy after IVF treatment in women with male-factor infertility"],"prefix":"10.3389","volume":"17","author":[{"given":"Ningning","family":"Chen","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, The Third Affiliated Hospital of Zhengzhou University","place":["Zhengzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaopei","family":"Guo","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, The Third Affiliated Hospital of Zhengzhou University","place":["Zhengzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junjie","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, The Third Affiliated Hospital of Zhengzhou University","place":["Zhengzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Shi","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, The Third Affiliated Hospital of Zhengzhou University","place":["Zhengzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaohua","family":"Luo","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, The Third Affiliated Hospital of Zhengzhou University","place":["Zhengzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,7,17]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.cd010001.pub2","article-title":"Vasodilators for women undergoing fertility treatment","volume":"3","author":"Gutarra-Vilchez","year":"2025","journal-title":"Cochrane Database Syst Rev"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.3389\/frph.2022.863173","article-title":"Non-invasive and mechanism-based molecular assessment of endometrial receptivity during the window of implantation: Current concepts and future prospective testing 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