{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T05:30:46Z","timestamp":1767850246640,"version":"3.49.0"},"reference-count":24,"publisher":"Frontiers Media SA","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Front. Genet."],"DOI":"10.3389\/fgene.2014.00133","type":"journal-article","created":{"date-parts":[[2014,5,15]],"date-time":"2014-05-15T06:47:04Z","timestamp":1400136424000},"source":"Crossref","is-referenced-by-count":34,"title":["Molecular mechanisms for the inheritance of acquired characteristics\u00e2\u20ac\u201dexosomes, microRNA shuttling, fear and stress: Lamarck resurrected?"],"prefix":"10.3389","volume":"5","author":[{"given":"John","family":"Smythies","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lawrence","family":"Edelstein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vilayanur","family":"Ramachandran","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2014,5,15]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"714","DOI":"10.1016\/j.bbagrm.2012.12.011","article-title":"Control of maternal mRNA stability in germ cells and early embryos","volume":"1829","author":"Barckmann","year":"2013","journal-title":"Biochim. Biophys. Acta"},{"key":"B2","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1095\/biolreprod.113.110486","article-title":"Epididymosomes convey different repertoires of microRNAs throughout the bovine epididymis","volume":"89","author":"Belleann\u00c3\u00a9e","year":"2013","journal-title":"Biol. Reprod"},{"key":"B2a","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1038\/nn.3594","article-title":"Parental olfactory experience influences behavior and neural structure in subsequent generations","volume":"17","author":"Dias","year":"2014","journal-title":"Nat. Neurosci"},{"issue":"32","key":"B3","doi-asserted-by":"publisher","DOI":"10.3389\/fncel.2014.00032","article-title":"Epigenetic aspects of telocytes\/cordocytes: jacks of all trades, masters of most","volume":"8","author":"Edelstein","year":"2014","journal-title":"Front. Cell. Neurosci"},{"key":"B4","doi-asserted-by":"publisher","first-page":"4226","DOI":"10.1096\/fj.12-224048","article-title":"Paternal obesity initiates metabolic disturbances in two generations of mice with incomplete penetrance to the F2 generation and alters the transcriptional profile of testis and sperm microRNA content","volume":"27","author":"Fullston","year":"2013","journal-title":"FASEB J"},{"key":"B5","doi-asserted-by":"publisher","first-page":"667","DOI":"10.1038\/nn.3695","article-title":"Implication of sperm RNAs in transgenerational inheritance of the effects of early trauma in mice","volume":"17","author":"Gapp","year":"2014","journal-title":"Nat. Neurosci"},{"key":"B6","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1186\/1742-2094-11-68","article-title":"Exosomes as mediators of neuroinflammation","volume":"11","author":"Gupta","year":"2014","journal-title":"J. Neuroinflamm"},{"key":"B7","doi-asserted-by":"publisher","first-page":"118","DOI":"10.1186\/1752-0509-5-118","article-title":"Mechanisms of gap gene expression canalization in the Drosophila blastoderm","volume":"5","author":"Gursky","year":"2011","journal-title":"BMC Syst. Biol"},{"key":"B8","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1007\/BF00281206","article-title":"Linnaeus' Peloria: the history of a monster","volume":"54","author":"Gustaffson","year":"1979","journal-title":"Theor. Appl. Genet"},{"key":"B8a","doi-asserted-by":"publisher","first-page":"679","DOI":"10.1007\/s00441-012-1469-6","article-title":"Characterization and importance of microRNAs in mammalian gonadal function","volume":"349","author":"Hossain","year":"2012","journal-title":"Cell Tissue Res"},{"key":"B9","doi-asserted-by":"publisher","first-page":"604","DOI":"10.1093\/humupd\/dmt031","article-title":"The presence, role and clinical use of spermatozoal RNAs","volume":"19","author":"Jodar","year":"2013","journal-title":"Hum. Reprod. Update"},{"key":"B10","doi-asserted-by":"publisher","first-page":"590","DOI":"10.1007\/s12035-013-8544-1","article-title":"Exosomes: mediators of neurodegeneration, neuroprotection and therapeutics","volume":"49","author":"Kalani","year":"2014","journal-title":"Mol. Neurobiol"},{"key":"B11","doi-asserted-by":"publisher","first-page":"e44542","DOI":"10.1371\/journal.pone.0044542","article-title":"Novel small noncoding RNAs in mouse spermatozoa, zygotes and early embryos","volume":"7","author":"Kawano","year":"2012","journal-title":"PLoS ONE"},{"key":"B12","doi-asserted-by":"publisher","first-page":"5","DOI":"10.6061\/clinics\/2013(Sup01)02","article-title":"Novel insights into the genetic and epigenetic paternal contribution to the human embryo","volume":"68","author":"Kumar","year":"2013","journal-title":"Clinics (Sao. Paulo)"},{"key":"B13","doi-asserted-by":"publisher","first-page":"432","DOI":"10.4161\/epi.19794","article-title":"Smoking induces differential miRNA expression in human spermatozoa: a potential transgenerational epigenetic concern?","volume":"7","author":"Marczylo","year":"2012","journal-title":"Epigenetics"},{"key":"B14","doi-asserted-by":"publisher","first-page":"e55946","DOI":"10.1371\/journal.pone.0055946","article-title":"Canalization and control in automata networks: body segmentation in Drosophila melanogaster","volume":"8","author":"Marques-Pita","year":"2013","journal-title":"PLoS ONE"},{"key":"B15","doi-asserted-by":"publisher","first-page":"353","DOI":"10.1586\/14737175.2014.890893","article-title":"What are exosomes and how can they be used in multiple sclerosis therapy?","volume":"14","author":"Pusic","year":"2014","journal-title":"Expert Rev. Neurother"},{"key":"B16","doi-asserted-by":"publisher","first-page":"9003","DOI":"10.1523\/JNEUROSCI.0914-13.2013","article-title":"Paternal stress exposure alters sperm microrna content and reprograms offspring hpa stress axis regulation","volume":"33","author":"Rodgers","year":"2013","journal-title":"J. Neurosci"},{"key":"B17","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1161\/CIRCRESAHA.114.300639","article-title":"Exosomes and cardiac repair after myocardial infarction","volume":"114","author":"Sahoo","year":"2014","journal-title":"Circ. Res"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1007\/s13365-014-0238-6","article-title":"Exosomes and their role in CNS viral infections","author":"Sampey","year":"2014","journal-title":"J. Neurovirol"},{"issue":"126","key":"B19","doi-asserted-by":"publisher","DOI":"10.3389\/fnint.2012.00126","article-title":"Transsynaptic modality codes in the brain: possible involvement of synchronized spike timing, microRNAs, exosomes and epigenetic processes","volume":"6","author":"Smythies","year":"2013a","journal-title":"Front. Intregr. Neurosci"},{"issue":"278","key":"B20","doi-asserted-by":"publisher","DOI":"10.3389\/fncel.2013.00278","article-title":"Telocytes, exosomes, gap junctions and the cytoskeleton: the makings of a primitive nervous system?","volume":"7","author":"Smythies","year":"2013b","journal-title":"Front. Cell. Neurosci"},{"key":"B21","doi-asserted-by":"publisher","first-page":"R37","DOI":"10.1530\/REP-12-0526","article-title":"Fine-tuning evolution: germ-line epigenetics and inheritance","volume":"146","author":"Stringer","year":"2013","journal-title":"Reproduction"},{"key":"B22","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.bcmd.2005.03.005","article-title":"Role of exosomes in sperm maturation during the transit along the male reproductive tract","volume":"35","author":"Sullivan","year":"2005","journal-title":"Blood Cells Mol. Dis"}],"container-title":["Frontiers in Genetics"],"original-title":[],"deposited":{"date-parts":[[2015,2,18]],"date-time":"2015-02-18T20:18:35Z","timestamp":1424290715000},"score":1,"resource":{"primary":{"URL":"http:\/\/journal.frontiersin.org\/article\/10.3389\/fgene.2014.00133\/abstract"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,5,15]]},"references-count":24,"URL":"https:\/\/doi.org\/10.3389\/fgene.2014.00133","relation":{},"ISSN":["1664-8021"],"issn-type":[{"value":"1664-8021","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,5,15]]}}}