{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T13:51:16Z","timestamp":1762955476001},"reference-count":31,"publisher":"Frontiers Media SA","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Front. Genet."],"DOI":"10.3389\/fgene.2015.00249","type":"journal-article","created":{"date-parts":[[2015,7,22]],"date-time":"2015-07-22T08:37:40Z","timestamp":1437554260000},"source":"Crossref","is-referenced-by-count":11,"title":["FOXP3 is a promising and potential candidate gene in generalised vitiligo susceptibility"],"prefix":"10.3389","volume":"6","author":[{"given":"Parveen","family":"Jahan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Surekha","family":"Tippisetty","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Prasanna L.","family":"Komaravalli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2015,7,22]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"1","DOI":"10.5339\/qmj.2013.10","article-title":"Concise review of recent studies in vitiligo","volume":"2013","author":"Allam","year":"2013","journal-title":"Qatar. Med. J"},{"key":"B2","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1038\/83713","article-title":"The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3","volume":"27","author":"Bennett","year":"2001","journal-title":"Nat. Genet"},{"key":"B3","doi-asserted-by":"publisher","first-page":"798","DOI":"10.1038\/jid.2009.347","article-title":"Genome-wide association study of generalized vitiligo in an isolated European founder population identifies SMOC2, in close proximity to IDDM8","volume":"130","author":"Birlea","year":"2010","journal-title":"J. Invest. Dermatol"},{"key":"B4","doi-asserted-by":"publisher","first-page":"371","DOI":"10.1038\/jid.2010.337","article-title":"Comprehensive Association Analysis of Candidate Genes for Generalized Vitiligo Supports XBP1, FOXP3, and TSLP","volume":"131","author":"Birlea","year":"2011","journal-title":"J. Invest. Dermatol"},{"key":"B5","doi-asserted-by":"publisher","first-page":"1285","DOI":"10.1038\/jid.2013.540","article-title":"A quantitative increase in regulatory T cells controls development of vitiligo","volume":"134","author":"Chatterjee","year":"2014","journal-title":"J. Invest. Dermatol"},{"key":"B6","doi-asserted-by":"publisher","first-page":"1057","DOI":"10.1086\/430279","article-title":"A novel linkage to generalized vitiligo on 4q13-q21 identified in a genomewide linkage analysis of Chinese families","volume":"76","author":"Chen","year":"2005","journal-title":"Am. J. Hum. Genet"},{"key":"B7","doi-asserted-by":"publisher","first-page":"279","DOI":"10.4103\/2229-5178.120637","article-title":"Study of oxidative stress in peripheral blood of Indian vitiligo patients","volume":"4","author":"Deo","year":"2013","journal-title":"Indian. Dermatol. Online. J"},{"key":"B8","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1016\/j.autrev.2014.10.002","article-title":"Regulatory T cells in vitiligo: implications for pathogenesis and therapeutics","volume":"14","author":"Dwivedi","year":"2015","journal-title":"Autoimmun. Rev"},{"key":"B9","doi-asserted-by":"publisher","first-page":"586","DOI":"10.1111\/pcmr.12105","article-title":"Decreased regulatory T-cells and CD4(+) \/CD8(+) ratio correlate with disease onset and progression in patients with generalized vitiligo","volume":"26","author":"Dwivedi","year":"2013","journal-title":"Pigment Cell Melanoma Res"},{"key":"B10","doi-asserted-by":"publisher","first-page":"262","DOI":"10.1016\/j.jaad.2013.01.035","article-title":"Association of FOXP3 (rs3761548) promoter polymorphism with nondermatomal vitiligo: a study from India","volume":"69","author":"Jahan","year":"2013","journal-title":"J. Am. Acad. Dermatol"},{"key":"B12","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1007\/s12291-010-0045-7","article-title":"Study of oxidative stress in vitiligo","volume":"26","author":"Jain","year":"2011","journal-title":"Indian. J. Clin. Biochem"},{"key":"B13","doi-asserted-by":"publisher","first-page":"576","DOI":"10.1038\/ng.602","article-title":"Common variants in FOXP1 are associated with generalized vitiligo","volume":"42","author":"Jin","year":"2010","journal-title":"Nat. Genet"},{"key":"B14","doi-asserted-by":"publisher","first-page":"276","DOI":"10.1111\/j.1755-148X.2010.00688.x","article-title":"Reduced skin homing by functional Treg in vitiligo","volume":"23","author":"Klarquist","year":"2010","journal-title":"Pigment. Cell Melanoma. Res"},{"key":"B15","doi-asserted-by":"publisher","first-page":"1206","DOI":"10.1111\/j.1365-4632.2011.05377.x","article-title":"A review of the worldwide prevalence of vitiligo in children\/adolescents and adults","volume":"51","author":"Kr\u00fcger","year":"2012","journal-title":"Int. J. Dermatol"},{"key":"B16","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1111\/exd.12103","article-title":"Vitiligo: interplay between oxidative stress and immune system","volume":"22","author":"Laddha","year":"2013","journal-title":"Exp. Dermatol"},{"key":"B17","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1084\/jem.20061852","article-title":"Selective depletion of Foxp3+ regulatory T cells induces a scurfy-like disease","volume":"204","author":"Lahl","year":"2007","journal-title":"J. Exp. Med"},{"key":"B18","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1111\/j.1600-0625.1993.tb00023.x","article-title":"Review of the etiopathomechanism of vitiligo: a convergence theory","volume":"2","author":"Le Poole","year":"1993a","journal-title":"Exp. Dermatol"},{"key":"B19","doi-asserted-by":"publisher","first-page":"e37513","DOI":"10.1371\/journal.pone.0037513","article-title":"Global Activation of CD8+Cytotoxic T Lymphocytes Correlates with an Impairment in Regulatory T Cells in Patients with Generalized Vitiligo","volume":"7","author":"Lili","year":"2012","journal-title":"PLoS. ONE"},{"key":"B20","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1111\/j.1365-4632.2006.02848.x","article-title":"Vitiligo prevalence study in Shaanxi Province, China","volume":"46","author":"Lu","year":"2007","journal-title":"Int. J. Dermatol"},{"key":"B21","doi-asserted-by":"publisher","first-page":"701","DOI":"10.4103\/0378-6323.45144","article-title":"Clinical and sociodemographic study of vitiligo","volume":"74","author":"Shah","year":"2008","journal-title":"Indian. J. Dermatol. Venereol. Leprol"},{"key":"B22","doi-asserted-by":"publisher","first-page":"226","DOI":"10.1111\/j.1582-4934.2008.00370.x","article-title":"Intron-1 rs3761548 is related to the defective transcription of Foxp3 in psoriasis through abrogating E47\/c-Myb binding","volume":"14","author":"Shen","year":"2010","journal-title":"J. Cell. Mol. Med"},{"key":"B23","doi-asserted-by":"publisher","first-page":"571","DOI":"10.1111\/bjd.12377","article-title":"Association between FOXP3 polymorphisms and vitiligo in a Han Chinese population","volume":"169","author":"Song","year":"2013","journal-title":"Br. J. Dermatol"},{"key":"B24","first-page":"25","article-title":"An association study of single nucleotide polymorphisms of the FOXP3 intron-1 and the risk of Psoriasis vulgaris","volume":"49","author":"Song","year":"2012","journal-title":"Indian. J. Biochem. Biophys"},{"key":"B25","doi-asserted-by":"publisher","first-page":"310","DOI":"10.1111\/1346-8138.12147","article-title":"Modern vitiligo genetics sheds new light on an ancient disease","volume":"40","author":"Spritz","year":"2013","journal-title":"J. Dermatol"},{"key":"B26","doi-asserted-by":"publisher","first-page":"403","DOI":"10.1038\/jid.2012.320","article-title":"Association analyses identify three susceptibility loci for vitiligo in the Chinese Han Population","volume":"133","author":"Tang","year":"2013","journal-title":"J. Invest. Dermatol"},{"key":"B27","doi-asserted-by":"publisher","first-page":"537","DOI":"10.1136\/jmg.39.8.537","article-title":"Clinical and molecular features of the immunodysregulation, polyendocrinopathy, enteropathy, X linked (IPEX) syndrome","volume":"39","author":"Wildin","year":"2002","journal-title":"J. Med. Genet"},{"key":"B28","doi-asserted-by":"publisher","first-page":"896458","DOI":"10.1155\/2012\/896458","article-title":"Association between functional polymorphisms of Foxp3 gene and the occurrence of unexplained recurrent spontaneous abortion in a Chinese Han Population","volume":"2012","author":"Wu","year":"2012","journal-title":"Clin. Develop. Immunol"},{"key":"B29","doi-asserted-by":"publisher","first-page":"1643","DOI":"10.1093\/intimm\/dxh165","article-title":"Crucial role of FOXP3 in the development and function of human CD25+ CD4+ regulatory T cells","volume":"16","author":"Yagi","year":"2004","journal-title":"Int. Immunol"},{"key":"B30","doi-asserted-by":"publisher","first-page":"936","DOI":"10.1038\/nature05563","article-title":"Genome-wide analysis of Foxp3 target genes in developing and mature regulatory T cells","volume":"445","author":"Zheng","year":"2007","journal-title":"Nature"},{"key":"B31","doi-asserted-by":"publisher","first-page":"457","DOI":"10.1038\/ni1455","article-title":"Foxp3 in control of the regulatory T cell lineage","volume":"8","author":"Zheng","year":"2007","journal-title":"Nat. Immunol"},{"key":"B32","doi-asserted-by":"publisher","first-page":"602","DOI":"10.1111\/j.1755-148X.2012.01019.x","article-title":"Systemic analyses of immunophenotypes of peripheral T cells in non-segmental vitiligo: implication of defective natural killer T cells","volume":"25","author":"Zhou","year":"2012","journal-title":"Pigment. Cell. Melanoma. Res"}],"container-title":["Frontiers in Genetics"],"original-title":[],"deposited":{"date-parts":[[2015,8,5]],"date-time":"2015-08-05T13:12:43Z","timestamp":1438780363000},"score":1,"resource":{"primary":{"URL":"http:\/\/journal.frontiersin.org\/Article\/10.3389\/fgene.2015.00249\/abstract"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,7,22]]},"references-count":31,"URL":"https:\/\/doi.org\/10.3389\/fgene.2015.00249","relation":{},"ISSN":["1664-8021"],"issn-type":[{"value":"1664-8021","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,7,22]]}}}