{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T06:46:31Z","timestamp":1793774791094,"version":"4.6.1"},"reference-count":72,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2018,9,25]],"date-time":"2018-09-25T00:00:00Z","timestamp":1537833600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["NIH R01 HL126732"],"award-info":[{"award-number":["NIH R01 HL126732"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000912","name":"March of Dimes Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000912","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Genet."],"DOI":"10.3389\/fgene.2018.00418","type":"journal-article","created":{"date-parts":[[2018,9,25]],"date-time":"2018-09-25T04:46:34Z","timestamp":1537850794000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":118,"title":["Fgf10 Signaling in Lung Development, Homeostasis, Disease, and Repair After Injury"],"prefix":"10.3389","volume":"9","author":[{"given":"Tingting","family":"Yuan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Volckaert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diptiman","family":"Chanda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victor J.","family":"Thannickal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stijn P.","family":"De Langhe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2018,9,25]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"1999","DOI":"10.1002\/dvdy.22032","article-title":"Conditional gene inactivation reveals roles for Fgf10 and Fgfr2 in establishing a normal pattern of epithelial branching in the mouse lung.","volume":"238","author":"Abler","year":"2009","journal-title":"Dev. Dyn."},{"key":"B2","doi-asserted-by":"publisher","first-page":"4139","DOI":"10.1242\/dev.109173","article-title":"Evidence for the involvement of fibroblast growth factor 10 in lipofibroblast formation during embryonic lung development.","volume":"142","author":"Al Alam","year":"2015","journal-title":"Development"},{"key":"B3","doi-asserted-by":"publisher","first-page":"11895","DOI":"10.1073\/pnas.96.21.11895","article-title":"Fgfr2 is required for limb outgrowth and lung-branching morphogenesis.","volume":"96","author":"Arman","year":"1999","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B4","doi-asserted-by":"publisher","first-page":"1600","DOI":"10.1242\/dev.135681","article-title":"FGFR2 is required for airway basal cell self-renewal and terminal differentiation.","volume":"144","author":"Balasooriya","year":"2017","journal-title":"Development"},{"key":"B5","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1016\/j.devcel.2016.03.001","article-title":"An FGFR1-SPRY2 signaling axis limits basal cell proliferation in the steady-state airway epithelium.","volume":"37","author":"Balasooriya","year":"2016","journal-title":"Dev. Cell"},{"key":"B6","doi-asserted-by":"publisher","first-page":"3025","DOI":"10.1172\/JCI68782","article-title":"Type 2 alveolar cells are stem cells in adult lung.","volume":"123","author":"Barkauskas","year":"2013","journal-title":"J. Clin. Invest."},{"key":"B7","doi-asserted-by":"crossref","first-page":"4867","DOI":"10.1242\/dev.124.23.4867","article-title":"Fibroblast growth factor 10 (FGF10) and branching morphogenesis in the embryonic mouse lung.","volume":"124","author":"Bellusci","year":"1997","journal-title":"Development"},{"key":"B8","doi-asserted-by":"publisher","first-page":"1360","DOI":"10.1164\/rccm.200209-1030OC","article-title":"Airway structural alterations selectively associated with severe asthma.","volume":"167","author":"Benayoun","year":"2003","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"B9","doi-asserted-by":"publisher","first-page":"L550","DOI":"10.1152\/ajplung.00329.2006","article-title":"FGF-10 is decreased in bronchopulmonary dysplasia and suppressed by Toll-like receptor activation.","volume":"292","author":"Benjamin","year":"2007","journal-title":"Am. J. Physiol. Lung Cell Mol. Physiol."},{"key":"B10","doi-asserted-by":"publisher","first-page":"1226","DOI":"10.1111\/jcmm.12269","article-title":"Keratinocyte growth factor-2 intratracheal instillation significantly attenuates ventilator-induced lung injury in rats.","volume":"18","author":"Bi","year":"2014","journal-title":"J. Cell Mol. Med."},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1038\/srep37445","article-title":"Developmental reprogramming in mesenchymal stromal cells of human subjects with idiopathic pulmonary fibrosis.","volume":"6","author":"Chanda","year":"2016","journal-title":"Sci. Rep."},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2015.00027","article-title":"A breath of fresh air on the mesenchyme: impact of impaired mesenchymal development on the pathogenesis of bronchopulmonary dysplasia.","volume":"2","author":"Chao","year":"2015","journal-title":"Front. Med."},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1186\/s40348-016-0045-7","article-title":"Alveologenesis: key cellular players and fibroblast growth factor 10 signaling.","volume":"3","author":"Chao","year":"2016","journal-title":"Mol. Cell Pediatr."},{"key":"B14","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1002\/path.4834","article-title":"Fgf10 deficiency is causative for lethality in a mouse model of bronchopulmonary dysplasia.","volume":"241","author":"Chao","year":"2017","journal-title":"J. Pathol."},{"key":"B15","doi-asserted-by":"publisher","first-page":"517","DOI":"10.1165\/rcmb.2012-0030OC","article-title":"Dynamic regulation of platelet-derived growth factor receptor alpha expression in alveolar fibroblasts during realveolarization.","volume":"47","author":"Chen","year":"2012","journal-title":"Am. J. Respir. Cell Mol. Biol."},{"key":"B16","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1016\/j.ydbio.2006.07.001","article-title":"Levels of mesenchymal FGFR2 signaling modulate smooth muscle progenitor cell commitment in the lung.","volume":"299","author":"De Langhe","year":"2006","journal-title":"Dev. Biol."},{"key":"B17","doi-asserted-by":"publisher","first-page":"316","DOI":"10.1016\/j.ydbio.2004.09.023","article-title":"Dickkopf-1 (DKK1) reveals that fibronectin is a major target of Wnt signaling in branching morphogenesis of the mouse embryonic lung.","volume":"277","author":"De Langhe","year":"2005","journal-title":"Dev. Biol."},{"key":"B18","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1242\/dev.127.3.483","article-title":"An important role for the IIIb isoform of fibroblast growth factor receptor 2 (FGFR2) in mesenchymal-epithelial signalling during mouse organogenesis.","volume":"127","author":"De Moerlooze","year":"2000","journal-title":"Development"},{"key":"B19","doi-asserted-by":"publisher","first-page":"190","DOI":"10.1038\/nature12930","article-title":"Alveolar progenitor and stem cells in lung development, renewal and cancer.","volume":"507","author":"Desai","year":"2014","journal-title":"Nature"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/538379","article-title":"Walking along the fibroblast growth factor 10 route: a key pathway to understand the control and regulation of epithelial and mesenchymal cell-lineage formation during lung development and repair after injury.","volume":"2014","author":"El Agha","year":"2014","journal-title":"Scientifica"},{"key":"B21","doi-asserted-by":"publisher","first-page":"296","DOI":"10.1242\/dev.099747","article-title":"Fgf10-positive cells represent a progenitor cell population during lung development and postnatally.","volume":"141","author":"El Agha","year":"2014","journal-title":"Development"},{"key":"B22","doi-asserted-by":"publisher","first-page":"261.e3","DOI":"10.1016\/j.stem.2017.03.011","article-title":"Two-Way conversion between lipogenic and myogenic fibroblastic phenotypes marks the progression and resolution of lung fibrosis.","volume":"20","author":"El Agha","year":"2017","journal-title":"Cell Stem Cell"},{"key":"B23","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1038\/ng1507","article-title":"Mutations in the gene encoding fibroblast growth factor 10 are associated with aplasia of lacrimal and salivary glands.","volume":"37","author":"Entesarian","year":"2005","journal-title":"Nat. Genet."},{"key":"B24","doi-asserted-by":"publisher","first-page":"1156","DOI":"10.1165\/rcmb.2013-0268OC","article-title":"Protective effects of keratinocyte growth factor-2 on ischemia-reperfusion-induced lung injury in rats.","volume":"50","author":"Fang","year":"2014","journal-title":"Am. J. Respir. Cell Mol. Biol."},{"key":"B25","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1101\/gad.10.2.165","article-title":"Keratinocyte growth factor is required for hair development but not for wound healing.","volume":"10","author":"Guo","year":"1996","journal-title":"Genes Dev."},{"key":"B26","doi-asserted-by":"publisher","first-page":"424","DOI":"10.1164\/rccm.200811-1794OC","article-title":"Overexpression of fibroblast growth factor-10 during both inflammatory and fibrotic phases attenuates bleomycin-induced pulmonary fibrosis in mice.","volume":"180","author":"Gupte","year":"2009","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"B27","doi-asserted-by":"publisher","first-page":"3855","DOI":"10.1073\/pnas.071586898","article-title":"A splicing switch and gain-of-function mutation in FgfR2-IIIc hemizygotes causes Apert\/Pfeiffer-syndrome-like phenotypes.","volume":"98","author":"Hajihosseini","year":"2001","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B28","doi-asserted-by":"publisher","first-page":"932","DOI":"10.1242\/jcs.092734","article-title":"beta-Catenin-SOX2 signaling regulates the fate of developing airway epithelium.","author":"Hashimoto","year":"2012","journal-title":"J. Cell Sci."},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.1186\/1471-213X-5-11","article-title":"FGF10\/FGFR2b signaling plays essential roles during in vivo embryonic submandibular salivary gland morphogenesis.","volume":"5","author":"Jaskoll","year":"2005","journal-title":"BMC Dev. Biol."},{"key":"B30","doi-asserted-by":"publisher","first-page":"1949","DOI":"10.1016\/S0140-6736(11)60052-4","article-title":"Idiopathic pulmonary fibrosis.","volume":"378","author":"King","year":"2011","journal-title":"Lancet"},{"key":"B31","doi-asserted-by":"publisher","first-page":"705","DOI":"10.1136\/jmedgenet-2011-100166","article-title":"Fibroblast growth factor 10 haploinsufficiency causes chronic obstructive pulmonary disease.","volume":"48","author":"Klar","year":"2011","journal-title":"J. Med. Genet."},{"key":"B32","doi-asserted-by":"publisher","first-page":"1149.e12","DOI":"10.1016\/j.cell.2017.07.028","article-title":"Anatomically and functionally distinct lung mesenchymal populations marked by Lgr5 and Lgr6.","volume":"170","author":"Lee","year":"2017","journal-title":"Cell"},{"key":"B33","doi-asserted-by":"publisher","first-page":"999","DOI":"10.1002\/stem.1911","article-title":"Progenitors of secondary crest myofibroblasts are developmentally committed in early lung mesoderm.","volume":"33","author":"Li","year":"2015","journal-title":"Stem Cells"},{"key":"B34","doi-asserted-by":"publisher","first-page":"297.e5","DOI":"10.1016\/j.devcel.2018.01.008","article-title":"The strength of mechanical forces determines the differentiation of alveolar epithelial cells.","volume":"44","author":"Li","year":"2018","journal-title":"Dev. Cell"},{"key":"B35","doi-asserted-by":"publisher","first-page":"2157","DOI":"10.1242\/dev.01795","article-title":"Fgf10 expression identifies parabronchial smooth muscle cell progenitors and is required for their entry into the smooth muscle cell lineage.","volume":"132","author":"Mailleux","year":"2005","journal-title":"Development"},{"key":"B36","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1016\/0925-4773(94)90050-7","article-title":"FGF-7 (keratinocyte growth factor) expression during mouse development suggests roles in myogenesis, forebrain regionalisation and epithelial-mesenchymal interactions.","volume":"45","author":"Mason","year":"1994","journal-title":"Mech. Dev."},{"key":"B37","doi-asserted-by":"publisher","first-page":"L463","DOI":"10.1152\/ajplung.00013.2015","article-title":"Fibroblast growth factor signaling in myofibroblasts differs from lipofibroblasts during alveolar septation in mice.","volume":"309","author":"McGowan","year":"2015","journal-title":"Am. J. Physiol. Lung Cell Mol. Physiol."},{"key":"B38","doi-asserted-by":"publisher","first-page":"3156","DOI":"10.1101\/gad.12.20.3156","article-title":"Fgf-10 is required for both limb and lung development and exhibits striking functional similarity to Drosophila branchless.","volume":"12","author":"Min","year":"1998","journal-title":"Genes Dev."},{"key":"B39","doi-asserted-by":"publisher","first-page":"319","DOI":"10.1038\/s41586-018-0393-7","article-title":"A revised airway epithelial hierarchy includes CFTR-expressing ionocytes.","volume":"560","author":"Montoro","year":"2018","journal-title":"Nature"},{"key":"B40","doi-asserted-by":"publisher","first-page":"643","DOI":"10.1006\/bbrc.2000.3721","article-title":"FGF10 acts as a major ligand for FGF receptor 2 IIIb in mouse multi-organ development.","volume":"277","author":"Ohuchi","year":"2000","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"B41","doi-asserted-by":"publisher","first-page":"446","DOI":"10.1086\/302245","article-title":"De novo alu-element insertions in FGFR2 identify a distinct pathological basis for Apert syndrome.","volume":"64","author":"Oldridge","year":"1999","journal-title":"Am. J. Hum. Genet."},{"key":"B42","doi-asserted-by":"publisher","DOI":"10.1242\/dev.160788","article-title":"Beta-Catenin maintains lung epithelial progenitors after lung specification.","volume":"2018","author":"Ostrin","year":"2018","journal-title":"Development"},{"key":"B43","doi-asserted-by":"publisher","first-page":"578","DOI":"10.1038\/nature14984","article-title":"Hedgehog actively maintains adult lung quiescence and regulates repair and regeneration.","volume":"526","author":"Peng","year":"2015","journal-title":"Nature"},{"key":"B44","doi-asserted-by":"publisher","first-page":"L299","DOI":"10.1152\/ajplung.00008.2009","article-title":"FGF signaling is required for myofibroblast differentiation during alveolar regeneration.","volume":"297","author":"Perl","year":"2009","journal-title":"Am. J. Physiol. Lung Cell Mol. Physiol."},{"key":"B45","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1242\/dev.114.1.233","article-title":"Two FGF receptor genes are differentially expressed in epithelial and mesenchymal tissues during limb formation and organogenesis in the mouse.","volume":"114","author":"Peters","year":"1992","journal-title":"Development"},{"key":"B46","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1005544","article-title":"Influenza virus infects epithelial stem\/progenitor cells of the distal lung: impact on Fgfr2b-Driven epithelial repair.","volume":"12","author":"Quantius","year":"2016","journal-title":"PLoS Pathog."},{"key":"B47","doi-asserted-by":"publisher","first-page":"237","DOI":"10.1016\/j.ydbio.2007.04.033","article-title":"Fgf10 dosage is critical for the amplification of epithelial cell progenitors and for the formation of multiple mesenchymal lineages during lung development.","volume":"307","author":"Ramasamy","year":"2007","journal-title":"Dev. Biol."},{"key":"B48","doi-asserted-by":"publisher","first-page":"1378","DOI":"10.1002\/dvdy.20461","article-title":"Intercellular growth factor signaling and the development of mouse tracheal submucosal glands.","volume":"233","author":"Rawlins","year":"2005","journal-title":"Dev. Dyn."},{"key":"B49","doi-asserted-by":"publisher","first-page":"525","DOI":"10.1016\/j.stem.2009.04.002","article-title":"The role of Scgb1a1 + Clara cells in the long-term maintenance and repair of lung airway, but not alveolar, epithelium.","volume":"4","author":"Rawlins","year":"2009","journal-title":"Cell Stem Cell"},{"key":"B50","doi-asserted-by":"publisher","first-page":"12771","DOI":"10.1073\/pnas.0906850106","article-title":"Basal cells as stem cells of the mouse trachea and human airway epithelium.","volume":"106","author":"Rock","year":"2009","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B51","doi-asserted-by":"publisher","first-page":"545","DOI":"10.1242\/dmm.006031","article-title":"Airway basal stem cells: a perspective on their roles in epithelial homeostasis and remodeling.","volume":"3","author":"Rock","year":"2010","journal-title":"Dis. Model. Mech."},{"key":"B52","doi-asserted-by":"publisher","first-page":"1225","DOI":"10.1242\/dev.00345","article-title":"Tbx4-Fgf10 system controls lung bud formation during chicken embryonic development.","volume":"130","author":"Sakiyama","year":"2003","journal-title":"Development"},{"key":"B53","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1242\/dev.051680","article-title":"FGF10 controls the patterning of the tracheal cartilage rings via Shh.","volume":"138","author":"Sala","year":"2011","journal-title":"Development"},{"key":"B54","doi-asserted-by":"publisher","first-page":"431","DOI":"10.1096\/fj.04-2879fje","article-title":"Submucosal gland dysfunction as a primary defect in cystic fibrosis.","volume":"19","author":"Salinas","year":"2005","journal-title":"FASEB J."},{"key":"B55","doi-asserted-by":"publisher","first-page":"138","DOI":"10.1038\/5096","article-title":"Fgf10 is essential for limb and lung formation.","volume":"21","author":"Sekine","year":"1999","journal-title":"Nat. Genet."},{"key":"B56","doi-asserted-by":"publisher","first-page":"3074","DOI":"10.1111\/j.1582-4934.2012.01588.x","article-title":"KGF-2 targets alveolar epithelia and capillary endothelia to reduce high altitude pulmonary oedema in rats.","volume":"16","author":"She","year":"2012","journal-title":"J. Cell Mol. Med."},{"key":"B57","doi-asserted-by":"publisher","first-page":"12461","DOI":"10.1073\/pnas.92.26.12461","article-title":"Pulmonary malformation in transgenic mice expressing human keratinocyte growth factor in the lung.","volume":"92","author":"Simonet","year":"1995","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B58","doi-asserted-by":"publisher","first-page":"E974","DOI":"10.1073\/pnas.1715564115","article-title":"Human airway branch variation and chronic obstructive pulmonary disease.","volume":"115","author":"Smith","year":"2018","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B59","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1146\/annurev-med-042711-142004","article-title":"Molecular mechanisms in progressive idiopathic pulmonary fibrosis.","volume":"64","author":"Steele","year":"2013","journal-title":"Annu. Rev. Med."},{"key":"B60","doi-asserted-by":"publisher","first-page":"896","DOI":"10.1016\/j.bbrc.2006.11.107","article-title":"Sprouty2 and Sprouty4 are essential for embryonic morphogenesis and regulation of FGF signaling.","volume":"352","author":"Taniguchi","year":"2007","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"B61","doi-asserted-by":"publisher","first-page":"395","DOI":"10.1146\/annurev.med.55.091902.103810","article-title":"Mechanisms of pulmonary fibrosis.","volume":"55","author":"Thannickal","year":"2004","journal-title":"Annu. Rev. Med."},{"key":"B62","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1016\/j.resp.2014.06.011","article-title":"Keratinocyte growth factor-2 is protective in lipopolysaccharide-induced acute lung injury in rats.","volume":"201","author":"Tong","year":"2014","journal-title":"Respir. Physiol. Neurobiol."},{"key":"B63","doi-asserted-by":"publisher","DOI":"10.1038\/srep21642","article-title":"Fibroblast growth factor-10 (FGF-10) mobilizes lung-resident mesenchymal stem cells and protects against acute lung injury.","volume":"6","author":"Tong","year":"2016","journal-title":"Sci. Rep."},{"key":"B64","doi-asserted-by":"publisher","first-page":"371","DOI":"10.1038\/nature13173","article-title":"Reconstructing lineage hierarchies of the distal lung epithelium using single-cell RNA-seq.","volume":"509","author":"Treutlein","year":"2014","journal-title":"Nature"},{"key":"B65","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1165\/rcmb.2003-0064OC","article-title":"Fibroblast growth factor-10 attenuates H2O2-induced alveolar epithelial cell DNA damage: role of MAPK activation and DNA repair.","volume":"31","author":"Upadhyay","year":"2004","journal-title":"Am. J. Respir. Cell Mol. Biol."},{"key":"B66","doi-asserted-by":"publisher","first-page":"3731","DOI":"10.1242\/dev.096560","article-title":"Localized Fgf10 expression is not required for lung branching morphogenesis but prevents differentiation of epithelial progenitors.","volume":"140","author":"Volckaert","year":"2013","journal-title":"Development"},{"key":"B67","doi-asserted-by":"publisher","DOI":"10.1186\/1755-1536-7-8","article-title":"Lung epithelial stem cells and their niches: Fgf10 takes center stage.","volume":"7","author":"Volckaert","year":"2014","journal-title":"Fibrogenesis Tissue Repair"},{"key":"B68","doi-asserted-by":"publisher","first-page":"4409","DOI":"10.1172\/JCI58097","article-title":"Parabronchial smooth muscle constitutes an airway epithelial stem cell niche in the mouse lung after injury.","volume":"121","author":"Volckaert","year":"2011","journal-title":"J. Clin. Invest."},{"key":"B69","doi-asserted-by":"publisher","first-page":"48.e5","DOI":"10.1016\/j.devcel.2017.09.003","article-title":"Fgf10-hippo epithelial-mesenchymal crosstalk maintains and recruits lung basal stem cells.","volume":"43","author":"Volckaert","year":"2017","journal-title":"Dev. Cell"},{"key":"B70","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1242\/dev.125.4.753","article-title":"Fibroblast growth factor receptor 2 (FGFR2)-mediated reciprocal regulation loop between FGF8 and FGF10 is essential for limb induction.","volume":"125","author":"Xu","year":"1998","journal-title":"Development"},{"key":"B71","doi-asserted-by":"publisher","first-page":"1559","DOI":"10.1016\/j.ajpath.2013.07.016","article-title":"Activated alveolar epithelial cells initiate fibrosis through secretion of mesenchymal proteins.","volume":"183","author":"Yang","year":"2013","journal-title":"Am. J. Pathol."},{"key":"B72","doi-asserted-by":"publisher","first-page":"752.e4","DOI":"10.1016\/j.devcel.2018.03.001","article-title":"Spatial-Temporal lineage restrictions of embryonic p63(+) progenitors establish distinct stem cell pools in adult airways.","volume":"44","author":"Yang","year":"2018","journal-title":"Dev. Cell"}],"container-title":["Frontiers in Genetics"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fgene.2018.00418\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,9,2]],"date-time":"2022-09-02T16:58:05Z","timestamp":1662137885000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fgene.2018.00418\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,9,25]]},"references-count":72,"alternative-id":["10.3389\/fgene.2018.00418"],"URL":"https:\/\/doi.org\/10.3389\/fgene.2018.00418","relation":{},"ISSN":["1664-8021"],"issn-type":[{"value":"1664-8021","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,9,25]]},"article-number":"418"}}