{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T00:36:49Z","timestamp":1769128609311,"version":"3.49.0"},"reference-count":38,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2019,5,24]],"date-time":"2019-05-24T00:00:00Z","timestamp":1558656000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Genet."],"DOI":"10.3389\/fgene.2019.00506","type":"journal-article","created":{"date-parts":[[2019,5,24]],"date-time":"2019-05-24T14:53:06Z","timestamp":1558709586000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":27,"title":["LINC00673 rs11655237 C>T Polymorphism Impacts Hepatoblastoma Susceptibility in Chinese Children"],"prefix":"10.3389","volume":"10","author":[{"given":"Tianyou","family":"Yang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiahao","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yang","family":"Wen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tianbao","family":"Tan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiliang","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jing","family":"Pan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chao","family":"Hu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuxiao","family":"Yao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiao","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yijuan","family":"Xin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suhong","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huimin","family":"Xia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jing","family":"He","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan","family":"Zou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2019,5,24]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"314","DOI":"10.7150\/ijbs.15001","article-title":"Pancreatic cancer genetics.","volume":"12","author":"Amundadottir","year":"2016","journal-title":"Int. J. Biol. Sci."},{"key":"B2","doi-asserted-by":"publisher","first-page":"95542","DOI":"10.18632\/oncotarget.20980","article-title":"Long noncoding RNA LINC00673 epigenetically suppresses KLF4 by interacting with EZH2 and DNMT1 in gastric cancer.","volume":"8","author":"Ba","year":"2017","journal-title":"Oncotarget"},{"key":"B3","doi-asserted-by":"publisher","first-page":"1220","DOI":"10.2174\/1389450118666170622091940","article-title":"LncRNA HOTAIR polymorphisms association with cancer susceptibility in different tumor types.","volume":"19","author":"Botti","year":"2018","journal-title":"Curr. Drug Targets"},{"key":"B4","doi-asserted-by":"publisher","first-page":"911","DOI":"10.1038\/ng.3341","article-title":"Common variation at 2p13.3, 3q29, 7p13 and 17q25.1 associated with susceptibility to pancreatic cancer.","volume":"47","author":"Childs","year":"2015","journal-title":"Nat. Genet."},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwj104","article-title":"Maternal and infant birth characteristics and hepatoblastoma.","volume":"163","author":"Colleen","year":"2006","journal-title":"Am. J. Epidemiol."},{"key":"B6","doi-asserted-by":"publisher","first-page":"1050","DOI":"10.1002\/cncr.22876","article-title":"Features predicting unresectability in hepatoblastoma.","volume":"110","author":"D\u2019Antiga","year":"2007","journal-title":"Cancer"},{"key":"B7","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1007\/s12029-014-9659-y","article-title":"Hepatoblastoma\u2013a rare liver tumor with review of literature.","volume":"45","author":"Devi","year":"2014","journal-title":"J. Gastrointest. Cancer"},{"key":"B8","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1016\/j.ijscr.2016.02.019","article-title":"Hepatoblastoma in childhood, long term survival achieved: 2 case reports and literature review.","volume":"21","author":"El Asmar","year":"2016","journal-title":"Int. J. Surg. Case Rep."},{"key":"B9","doi-asserted-by":"publisher","first-page":"3698","DOI":"10.1016\/j.jmb.2013.06.031","article-title":"Guided by RNAs: x-inactivation as a model for lncRNA function.","volume":"425","author":"Froberg","year":"2013","journal-title":"J. Mol. Biol."},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.3390\/ijms18061239","article-title":"Genomic insight into the role of lncRNA in cancer susceptibility.","volume":"18","author":"Gao","year":"2017","journal-title":"Int. J. Mol. Sci."},{"key":"B11","doi-asserted-by":"publisher","first-page":"445","DOI":"10.1046\/j.1460-9592.2000.00548.x","article-title":"Successful airway control with the laryngeal mask in an infant with beckwith-wiedemann syndrome and hepatoblastoma for central line catheterization.","volume":"10","author":"Goldman","year":"2010","journal-title":"Paediatr. Anaesth."},{"key":"B12","doi-asserted-by":"publisher","first-page":"1481","DOI":"10.1111\/jcmm.12836","article-title":"Association of potentially functional variants in the XPG gene with neuroblastoma risk in a chinese population.","volume":"20","author":"He","year":"2016","journal-title":"J. Cell. Mol. Med."},{"key":"B13","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.omtn.2018.01.003","article-title":"Association of common genetic variants in pre-microRNAs and neuroblastoma susceptibility: a two-center study in chinese children.","volume":"11","author":"He","year":"2018","journal-title":"Mol. Ther. Nucleic Acids"},{"key":"B14","doi-asserted-by":"publisher","first-page":"936","DOI":"10.1016\/j.tranon.2017.09.008","article-title":"Genetic variations of GWAS-identified genes and neuroblastoma susceptibility: a replication study in southern chinese children.","volume":"10","author":"He","year":"2017","journal-title":"Transl. Oncol."},{"key":"B15","doi-asserted-by":"publisher","first-page":"445","DOI":"10.1634\/theoncologist.5-6-445","article-title":"Childhood cancers: hepatoblastoma.","volume":"5","author":"Herzog","year":"2000","journal-title":"Oncologist"},{"key":"B16","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1016\/j.jpeds.2005.04.019","article-title":"The spectrum of APC mutations in children with hepatoblastoma from familial adenomatous polyposis kindreds.","volume":"147","author":"Hirschman","year":"2005","journal-title":"J. Pediatr."},{"key":"B17","doi-asserted-by":"publisher","first-page":"1014","DOI":"10.1016\/j.ymthe.2017.01.017","article-title":"Long noncoding RNA LINC00673 is activated by SP1 and exerts oncogenic properties by interacting with LSD1 and EZH2 in gastric cancer.","volume":"25","author":"Huang","year":"2017","journal-title":"Mol. Ther."},{"key":"B18","doi-asserted-by":"publisher","first-page":"1023","DOI":"10.1002\/ajmg.1320430621","article-title":"Risk of hepatoblastoma in familial adenomatous polyposis.","volume":"43","author":"Hughes","year":"2010","journal-title":"Am. J. Med. Genet."},{"key":"B19","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1016\/s0304-3835(99)00433-4","article-title":"Somatic mutations of beta-catenin play a crucial role in the tumorigenesis of sporadic hepatoblastoma.","volume":"152","author":"Jeng","year":"2000","journal-title":"Cancer Lett."},{"key":"B20","doi-asserted-by":"publisher","first-page":"D181","DOI":"10.1093\/nar\/gku1000","article-title":"lncRNASNP: a database of SNPs in lncRNAs and their potential functions in human and mouse.","volume":"43","author":"Jing","year":"2015","journal-title":"Nucleic Acids Res."},{"key":"B21","doi-asserted-by":"crossref","first-page":"2318","DOI":"10.18632\/oncotarget.1913","article-title":"Overexpression of lncRNA H19 enhances carcinogenesis and metastasis of gastric cancer.","volume":"5","author":"Li","year":"2014","journal-title":"Oncotarget"},{"key":"B22","doi-asserted-by":"publisher","first-page":"32696","DOI":"10.18632\/oncotarget.16158","article-title":"Long intergenic noncoding RNA 00673 promotes non-small-cell lung cancer metastasis by binding with EZH2 and causing epigenetic silencing of HOXA5.","volume":"8","author":"Ma","year":"2017","journal-title":"Oncotarget"},{"key":"B23","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1002\/mc.22261","article-title":"A functional lncRNA HOTAIR genetic variant contributes to gastric cancer susceptibility.","volume":"55","author":"Pan","year":"2016","journal-title":"Mol. Carcinog."},{"key":"B24","doi-asserted-by":"publisher","first-page":"484","DOI":"10.3390\/genes6030484","article-title":"Molecular and cellular mechanisms of action of tumour suppressor GAS5 lncRNA.","volume":"6","author":"Pickard","year":"2015","journal-title":"Genes"},{"key":"B25","doi-asserted-by":"publisher","first-page":"5170","DOI":"10.1002\/jcp.26332","article-title":"The 9p21 locus: a potential therapeutic target and prognostic marker in breast cancer.","volume":"233","author":"Rivand","year":"2017","journal-title":"J. Cell. Physiol."},{"key":"B26","doi-asserted-by":"publisher","first-page":"1275","DOI":"10.1007\/s00247-014-3000-6","article-title":"Relapse surveillance in AFP-positive hepatoblastoma: re-evaluating the role of imaging.","volume":"44","author":"Rojas","year":"2014","journal-title":"Pediatr. Radiol."},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2407-13-608","article-title":"Comprehensive analyses of imprinted differentially methylated regions reveal epigenetic and genetic characteristics in hepatoblastoma.","volume":"13","author":"Rumbajan","year":"2013","journal-title":"BMC Cancer"},{"key":"B28","doi-asserted-by":"publisher","first-page":"25558","DOI":"10.18632\/oncotarget.8338","article-title":"Upregulation of long intergenic noncoding RNA 00673 promotes tumor proliferation via LSD1 interaction and repression of NCALD in non-small-cell lung cancer.","volume":"7","author":"Shi","year":"2016","journal-title":"Oncotarget"},{"key":"B29","first-page":"136","article-title":"Hepatoblastoma.","volume":"11","author":"Stocker","year":"1994","journal-title":"Semin. Diagn. Pathol."},{"key":"B30","doi-asserted-by":"publisher","first-page":"508","DOI":"10.1007\/s003830000576","article-title":"High frequency of \u03b2-catenin mutations in hepatoblastoma.","volume":"17","author":"Udatsu","year":"2001","journal-title":"Pediatr. Surg. Int."},{"key":"B31","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1053\/j.sempedsurg.2011.10.011","article-title":"Hepatoblastoma: recent developments in research and treatment.","volume":"21","author":"von Schweinitz","year":"2012","journal-title":"Semin. Pediatr. Surg."},{"key":"B32","doi-asserted-by":"publisher","DOI":"10.1177\/1073274818803942","article-title":"LINC00673 rs11655237 polymorphism is associated with increased risk of cervical cancer in a chinese population.","volume":"25","author":"Wang","year":"2018","journal-title":"Cancer Control"},{"key":"B33","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1016\/j.canlet.2013.06.013","article-title":"Long non-coding RNAs: a new frontier in the study of human diseases.","volume":"339","author":"Xuefei","year":"2013","journal-title":"Cancer Lett."},{"key":"B34","doi-asserted-by":"crossref","first-page":"15311","DOI":"10.18632\/oncotarget.3840","article-title":"Tag SNPs in long non-coding RNA H19 contribute to susceptibility to gastric cancer in the chinese han population.","volume":"6","author":"Yang","year":"2015","journal-title":"Oncotarget"},{"key":"B35","doi-asserted-by":"publisher","first-page":"16621","DOI":"10.18632\/oncotarget.14200","article-title":"Overexpression long non-coding RNALINC00673is associated with poor prognosis and promotes invasion and metastasis in tongue squamous cell carcinoma.","volume":"8","author":"Yu","year":"2017","journal-title":"Oncotarget"},{"key":"B36","first-page":"2536","article-title":"Long non-coding RNA LINC00673 promotes hepatocellular carcinoma progression and metastasis through negatively regulating miR-205.","volume":"7","author":"Zhang","year":"2017","journal-title":"Am. J. Cancer Res."},{"key":"B37","doi-asserted-by":"publisher","DOI":"10.1042\/BSR20171667","article-title":"LINC00673 rs11655237 C > T confers neuroblastoma susceptibility in chinese population.","volume":"38","author":"Zhang","year":"2018","journal-title":"Biosci. Rep."},{"key":"B38","doi-asserted-by":"publisher","first-page":"747","DOI":"10.1038\/ng.3568","article-title":"Pancreatic cancer risk variant in LINC00673 creates a miR-1231 binding site and interferes with PTPN11 degradation.","volume":"48","author":"Zheng","year":"2016","journal-title":"Nat. Genet."}],"container-title":["Frontiers in Genetics"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fgene.2019.00506\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,12,15]],"date-time":"2020-12-15T13:32:34Z","timestamp":1608039154000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fgene.2019.00506\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,5,24]]},"references-count":38,"alternative-id":["10.3389\/fgene.2019.00506"],"URL":"https:\/\/doi.org\/10.3389\/fgene.2019.00506","relation":{},"ISSN":["1664-8021"],"issn-type":[{"value":"1664-8021","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,5,24]]},"article-number":"506"}}