{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T20:03:46Z","timestamp":1784577826572,"version":"3.55.0"},"reference-count":22,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2020,11,16]],"date-time":"2020-11-16T00:00:00Z","timestamp":1605484800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Genet."],"DOI":"10.3389\/fgene.2020.594091","type":"journal-article","created":{"date-parts":[[2020,11,16]],"date-time":"2020-11-16T09:02:01Z","timestamp":1605517321000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":11,"title":["Expanded Carrier Screening in Chinese Population \u2013 A Survey on Views and Acceptance of Pregnant and Non-Pregnant Women"],"prefix":"10.3389","volume":"11","author":[{"given":"Hiu Yee Heidi","family":"Cheng","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Grace Ching Yin","family":"Wong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuen-Kwong Kelvin","family":"Chan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chin Peng","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary Hoi Yin","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ernest Hung-Yu","family":"Ng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anita Sik-Yau","family":"Kan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2020,11,16]]},"reference":[{"key":"B1","doi-asserted-by":"crossref","first-page":"e35","DOI":"10.1097\/AOG.0000000000001951","article-title":"Committee opinion no. 690: carrier screening in the age of genomic medicine.","volume":"129","year":"2017","journal-title":"Obstet. Gynecol."},{"key":"B2","first-page":"677","article-title":"Genetic disorders in children and young adults: a population study.","volume":"42","author":"Baird","year":"1988","journal-title":"Am. J. Hum. Genet."},{"key":"B3","doi-asserted-by":"publisher","first-page":"1948","DOI":"10.1038\/s41436-019-0455-8","article-title":"Clinical impact and cost-effectiveness of a 176-condition expanded carrier screen.","volume":"21","author":"Beauchamp","year":"2019","journal-title":"Genet. Med."},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1097\/01.aog.0000514924.67415.e7","article-title":"Patients\u2019 awareness and attitudes towards genetic carrier screening [22H].","volume":"129","author":"Briggs","year":"2017","journal-title":"Obstet. Gynecol."},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0200139","article-title":"Assessment of willingness to pay for expanded carrier screening among women and couples undergoing preconception carrier screening.","volume":"13","author":"Clarke","year":"2018","journal-title":"PLoS One"},{"key":"B6","article-title":"GM2 Gangliosidoses \u2013 Introduction and Epidemiology Archived 2012-04-20 at the Wayback Machine at Medscape","author":"David","year":"2012"},{"key":"B7","doi-asserted-by":"publisher","first-page":"653","DOI":"10.1097\/aog.0000000000000666","article-title":"Expanded carrier screening in reproductive medicine\u2014points to consider: a joint statement of the American College of Medical Genetics and Genomics, American College of Obstetricians and Gynecologists, National Society of Genetic Counselors, Perinatal Quality Foundation, and Society for Maternal-Fetal Medicine.","volume":"125","author":"Edwards","year":"2015","journal-title":"Obstet. Gynecol."},{"key":"B8","doi-asserted-by":"publisher","first-page":"734","DOI":"10.1001\/jama.2016.11139","article-title":"Modeled fetal risk of genetic diseases identified by expanded carrier screening.","volume":"316","author":"Haque","year":"2016","journal-title":"JAMA"},{"key":"B9","doi-asserted-by":"publisher","first-page":"412","DOI":"10.4236\/ojog.2015.57059","article-title":"An expanded carrier screening tool enhances preconception cystic fibrosis screening in infertile couples.","volume":"5","author":"Higgins","year":"2015","journal-title":"Open J. Obstet. Gynecol."},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1186\/s12910-017-0206-9","article-title":"Pre-and post-testing counseling considerations for the provision of expanded carrier screening: exploration of European geneticists\u2019 views.","volume":"18","author":"Janssens","year":"2017","journal-title":"BMC Med. Ethics"},{"key":"B11","first-page":"1","article-title":"The prevalence of thalassemia in mainland China: evidence from epidemiological surveys.","volume":"7","author":"Lai","year":"2017","journal-title":"Sci. Rep."},{"key":"B12","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1002\/pd.4532","article-title":"Current controversies in prenatal diagnosis 4: pre-conception expanded carrier screening should replace all current prenatal screening for specific single gene disorders.","volume":"35","author":"Langlois","year":"2015","journal-title":"Prenat. Diagn."},{"key":"B13","doi-asserted-by":"publisher","first-page":"319","DOI":"10.1002\/pd.5434","article-title":"The uptake of pan-ethnic expanded carrier screening is higher when offered during preconception or early prenatal genetic counseling.","volume":"39","author":"Larsen","year":"2019","journal-title":"Prenat. Diagn."},{"key":"B14","doi-asserted-by":"publisher","first-page":"823","DOI":"10.1007\/s10897-017-0205-5","article-title":"Time costs for genetic counseling in preconception carrier screening with genome sequencing.","volume":"27","author":"Lynch","year":"2018","journal-title":"J. Genet. Couns."},{"key":"B15","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1111\/j.2044-8260.1992.tb00997.x","article-title":"The development of a six-item short\u2212form of the state scale of the Spielberger State-Trait Anxiety Inventory (STAI).","volume":"31","author":"Marteau","year":"1992","journal-title":"Br. J. Clin. Psychol."},{"key":"B16","article-title":"Cystic fibrosis prevalence among a group of high-risk children in the main referral children hospital in Iran.","volume":"6","author":"Modaresi","year":"2017","journal-title":"J. Educ. Health Promot."},{"key":"B17","doi-asserted-by":"publisher","first-page":"1148","DOI":"10.1007\/s10897-018-0232-x","article-title":"Pregnant women\u2019s perspectives on expanded carrier screening.","volume":"27","author":"Propst","year":"2018","journal-title":"J. Genet. Couns."},{"key":"B18","doi-asserted-by":"publisher","first-page":"146","DOI":"10.1590\/s1516-31802001000400007","article-title":"The frequency of Tay-Sachs disease causing mutations in the Brazilian Jewish population justifies a carrier screening program.","volume":"119","author":"Rozenberg","year":"2001","journal-title":"Sao Paulo Med. J."},{"key":"B19","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1016\/s1383-5742(98)00012-x","article-title":"Ionizing radiation and genetic risks: IX. Estimates of the frequencies of mendelian diseases and spontaneous mutation rates in human populations: a 1998 perspective.","volume":"411","author":"Sankaranarayanan","year":"1998","journal-title":"Mutat. Res. Rev. Mutat. Res."},{"key":"B20","doi-asserted-by":"publisher","first-page":"691","DOI":"10.1038\/s41431-019-0351-3","article-title":"Feasibility of couple-based expanded carrier screening offered by general practitioners.","volume":"27","author":"Schuurmans","year":"2019","journal-title":"Eur. J. Hum. Genet."},{"key":"B21","volume":"49","year":"1994","journal-title":"Sources and effects of ionizing radiation: United Nations Scientific Committee on the Effects of Atomic Radiation: UNSCEAR 1994 Report to the General Assembly, with Scientific Annexes"},{"key":"B22","doi-asserted-by":"publisher","first-page":"254","DOI":"10.1038\/s41431-018-0253-9","article-title":"Pilot study of expanded carrier screening for 11 recessive diseases in China: results from 10,476 ethnically diverse couples.","volume":"27","author":"Zhao","year":"2019","journal-title":"Eur. J. Hum. Genet."}],"container-title":["Frontiers in Genetics"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fgene.2020.594091\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,11,16]],"date-time":"2020-11-16T09:02:06Z","timestamp":1605517326000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fgene.2020.594091\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,11,16]]},"references-count":22,"alternative-id":["10.3389\/fgene.2020.594091"],"URL":"https:\/\/doi.org\/10.3389\/fgene.2020.594091","relation":{},"ISSN":["1664-8021"],"issn-type":[{"value":"1664-8021","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,11,16]]},"article-number":"594091"}}