{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T13:38:58Z","timestamp":1791639538506,"version":"4.3.4"},"reference-count":23,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2022,9,28]],"date-time":"2022-09-28T00:00:00Z","timestamp":1664323200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Genet."],"abstract":"<jats:p>This study aims to evaluate the incidence of low birth weight (LBW) and related maternal risk factors (during pregnancy or childbirth) and neonatal outcomes. A retrospective cross-sectional study design was used to select 7,421 pregnant women who gave birth in our hospital from January 2018 to June 2021. The data were analyzed using STATA 14.1, and the dependent variable (LBW) and risk were analyzed by the chi-square test of independence. The association between factors is used to determine the factors related to LBW through bivariate and multivariate logistic regression. The incidence of LBW in this study was 4.77%. Compared with single pregnant women, the probability of newborn LBW in married pregnant women is 40% lower (AOR = 0.60 95%CI: 0.40\u20130.90, <jats:italic>p<\/jats:italic> = 0.013). Compared with gestational age less than 37\u00a0weeks, the LBW probability of gestational age 37\u201342 and 42\u00a0weeks or older is 85 and 81% lower respectively (AOR = 0.15 95% CI: 0.10\u20130.24, <jats:italic>p<\/jats:italic> = 0.001; AOR = 0.19 95 %CI: 0.09\u201338, <jats:italic>p<\/jats:italic> = 0.001), compared with normal pregnant women, the probability of neonatal LBW among pregnant women with hypertension is 94% higher [AOR = 1.94 (95% CI: 1.39\u20132.74, <jats:italic>p<\/jats:italic> = 0.001). Compared with neonates with normal birth weight, neonates with LBW are at Apgar 1\u00a0min And Apgar 5\u00a0min score is lower than 7 (AOR = 0.52 95%CI: 0.37\u20130.73, <jats:italic>p<\/jats:italic> = 0.001, AOR = 0.54 95%CI: 0.38\u20130.75, <jats:italic>p<\/jats:italic> = 0.001) higher risk. In conclusion, women\u2019s marital status (single), gestational age (&amp;lt;37\u00a0weeks), and combined hypertension are independently associated with LBW, and the higher risk of Apgar 1\u00a0min and Apgar 5\u00a0min scores &amp;lt;7 is an independent result of LBW.<\/jats:p>","DOI":"10.3389\/fgene.2022.1019321","type":"journal-article","created":{"date-parts":[[2022,9,28]],"date-time":"2022-09-28T07:31:58Z","timestamp":1664350318000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":12,"title":["Maternal risk factors and neonatal outcomes associated with low birth weight"],"prefix":"10.3389","volume":"13","author":[{"given":"Yang","family":"Shaohua","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zheng","family":"Bin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liu","family":"Mei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhai","family":"Jingfei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiao","family":"Pingping","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"He","family":"Yanping","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhu","family":"Liping","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Jiexin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mao","family":"Guoshun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2022,9,28]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"388","DOI":"10.1186\/s12884-017-1575-2","article-title":"Perinatal outcomes of hypertensive disorders in pregnancy at a tertiary hospital in Ghana","volume":"17","author":"Adu-Bonsaffoh","year":"2017","journal-title":"BMC Pregnancy Childbirth"},{"key":"B2","doi-asserted-by":"publisher","first-page":"200","DOI":"10.1016\/j.midw.2016.06.016","article-title":"Prevalence of low birth weight, macrosomia and stillbirth and their relationship to associated maternal risk factors in Hohoe Municipality, Ghana","volume":"40","author":"Agbozo","year":"2016","journal-title":"Midwifery"},{"key":"B3","doi-asserted-by":"publisher","first-page":"02062077","DOI":"10.1371\/journal.pone.0206207","article-title":"Socio-demographic determinants of low birth weight: Evidence from the kassena-nankana districts of the upper east region of Ghana","volume":"13","author":"Agorinya","year":"2018","journal-title":"PloS One"},{"key":"B4","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1007\/s11906-017-0757-7","article-title":"Pathophysiology and current clinical management of preeclampsia","volume":"19","author":"Amaral","year":"2017","journal-title":"Curr. 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