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Gene ontology studies have indicated possible role of miR-324 in responses of cells to the leukemia inhibitory factor, long-term synaptic potentiation, positive regulation of cytokines production and sensory perception of sound. In human, miR-324 is encoded by <jats:italic>MIR324<\/jats:italic> gene which resides on chromosome 17p13.1. In the current manuscript, we provide a concise review of the role of miR-324 in the pathogenesis of cancers as well as non-cancerous conditions such as aneurysmal subarachnoid hemorrhage, diabetic nephropathy, epilepsy, pulmonary\/renal fibrosis, ischemic stroke and ischemia reperfusion injuries. Moreover, we summarize the role of this miRNA as a prognostic marker for malignant disorders.<\/jats:p>","DOI":"10.3389\/fgene.2022.950162","type":"journal-article","created":{"date-parts":[[2022,8,10]],"date-time":"2022-08-10T04:34:29Z","timestamp":1660106069000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":11,"title":["A review on the role of miRNA-324 in various diseases"],"prefix":"10.3389","volume":"13","author":[{"given":"Sepideh","family":"Kadkhoda","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bashdar Mahmud","family":"Hussen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Solat","family":"Eslami","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soudeh","family":"Ghafouri-Fard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2022,8,10]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"e68054","DOI":"10.7554\/eLife.68054","article-title":"SMA-miRs (miR-181a-5p, -324-5p, and -451a) are overexpressed in spinal muscular atrophy skeletal muscle and serum samples","volume":"1","author":"Abiusi","year":"2021","journal-title":"eLife"},{"key":"B2","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1016\/j.jpsychires.2014.05.020","article-title":"Serum and amygdala microRNA signatures of posttraumatic stress: Fear correlation and biomarker potential","volume":"57","author":"Balakathiresan","year":"2014","journal-title":"J. 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