{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T05:19:32Z","timestamp":1783487972698,"version":"3.55.0"},"reference-count":28,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T00:00:00Z","timestamp":1783468800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Gastroenterol."],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Post-endoscopy gastric cancer (PEGC), defined as gastric cancer diagnosed after a negative upper gastrointestinal endoscopy, is considered a key indicator of endoscopic quality. Although international studies estimate that PEGC accounts for 5\u201311% of gastric cancer cases, evidence from Latin America remains scarce.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a retrospective multicentre observational study across three tertiary hospitals in Bogot\u00e1, Colombia (2024\u20132025). Adult patients with histologically confirmed gastric neoplasms were included. PEGC was defined as cancer diagnosed between 6 and 36 months after a negative endoscopy. Clinical characteristics, tumour location, and hospital outcomes were compared between PEGC and non-PEGC cases.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Amongst 599 patients, 71 met criteria for PEGC, corresponding to a frequency of 11.9% (95% CI: 9.5\u201314.7). Helicobacter pylori positivity was 67.1% overall and 70.4% amongst PEGC cases. PEGC was associated with higher rates of palliative management (23.9% vs 2.8%; OR 10.77; 95% CI: 5.09\u201322.77; p&amp;lt;0.001) and increased in-hospital mortality (16.9% vs 7.0%; OR 2.70; 95% CI: 1.33\u20135.46; p=0.004).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>PEGC was frequent in this Colombian cohort and associated with adverse hospital outcomes, highlighting missed diagnostic opportunities and the need to strengthen endoscopic quality standards in high-burden regions. These findings support the incorporation of PEGC rate as a quality indicator for upper gastrointestinal endoscopy in high-incidence regions.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fgstr.2026.1823329","type":"journal-article","created":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T04:52:50Z","timestamp":1783486370000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Post-endoscopy gastric cancer in Latin America: a multicentre cohort study from Colombia"],"prefix":"10.3389","volume":"5","author":[{"given":"Hernando","family":"Marulanda-Fernandez","sequence":"first","affiliation":[{"name":"Division of Gastroenterology, Universidad Nacional de Colombia","place":["Bogot\u00e1, Colombia"]},{"name":"Division of Gastroenterology and Digestive Endoscopy, Hospital Central de la Polic\u00eda","place":["Bogot\u00e1, Colombia"]},{"name":"Division of Gastroenterology and Digestive Endoscopy, Hospital Occidente de Kennedy","place":["Bogot\u00e1, Colombia"]},{"name":"Division of Gastroenterology and Digestive Endoscopy, Hospital Santa Clara","place":["Bogot\u00e1, Colombia"]},{"name":"Department of Gastroenterology, Center for Gastroenterology and Endoscopy","place":["Bogot\u00e1, Colombia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan Sebasti\u00e1n","family":"Fr\u00edas Ordo\u00f1ez","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Universidad Nacional de Colombia","place":["Bogot\u00e1, Colombia"]},{"name":"Division of Gastroenterology, Hospital Internacional de Colombia","place":["Bucaramanga, Colombia"]},{"name":"Research Group in Medical and Surgical Specialties, Fundaci\u00f3n Cardiovascular de Colombia","place":["Floridablanca, Colombia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gilberto","family":"Jaramillo Trujillo","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Universidad Nacional de Colombia","place":["Bogot\u00e1, Colombia"]},{"name":"Division of Gastroenterology, Hospital San Rafael de Facatativ\u00e1","place":["Cundinamarca, Colombia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juli\u00e1n","family":"Parga Berm\u00fadez","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Universidad Nacional de Colombia","place":["Bogot\u00e1, Colombia"]},{"name":"Division of Gastroenterology, Hospital El Tunal","place":["Bogot\u00e1, Colombia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean Sebasti\u00e1n","family":"Barrero G\u00f3mez","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Digestive Endoscopy, Hospital Occidente de Kennedy","place":["Bogot\u00e1, Colombia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia Valentina","family":"Monsalve Rico","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and 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