{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T15:28:32Z","timestamp":1791300512895,"version":"4.1.0"},"reference-count":178,"publisher":"Frontiers Media SA","content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Immunol."],"DOI":"10.3389\/fimmu.2017.00521","type":"journal-article","created":{"date-parts":[[2017,5,9]],"date-time":"2017-05-09T00:42:46Z","timestamp":1494290566000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":384,"title":["Thyroid Autoimmunity: Role of Anti-thyroid Antibodies in Thyroid and Extra-Thyroidal Diseases"],"prefix":"10.3389","volume":"8","author":[{"given":"Eleonore","family":"Fr\u00f6hlich","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Wahl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2017,5,9]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"197","DOI":"10.1016\/j.jaut.2009.09.008","article-title":"Recent insights in the epidemiology of autoimmune diseases: improved prevalence estimates and understanding of clustering of diseases","volume":"33","author":"Cooper","year":"2009","journal-title":"J Autoimmun"},{"key":"B2","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1016\/S1568-9972(03)00006-5","article-title":"The epidemiology of autoimmune diseases","volume":"2","author":"Cooper","year":"2003","journal-title":"Autoimmun Rev"},{"key":"B3","doi-asserted-by":"publisher","first-page":"252","DOI":"10.1007\/s12020-012-9703-2","article-title":"The incidence and prevalence of thyroid autoimmunity","volume":"42","author":"McLeod","year":"2012","journal-title":"Endocrine"},{"key":"B4","first-page":"360","article-title":"Thyroid-directed antibodies","volume-title":"Part II Laboratory Assessment of Thyroid Function","author":"Marcocci","year":"2005"},{"key":"B5","doi-asserted-by":"publisher","first-page":"114","DOI":"10.1210\/er.2015-1098","article-title":"TSH receptor cleavage into subunits and shedding of the A-subunit; a molecular and clinical perspective","volume":"37","author":"Rapoport","year":"2016","journal-title":"Endocr Rev"},{"key":"B6","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1007\/s13317-012-0028-1","article-title":"Blocking type TSH receptor antibodies","volume":"4","author":"Furmaniak","year":"2013","journal-title":"Auto Immun Highlights"},{"key":"B7","doi-asserted-by":"publisher","first-page":"5537","DOI":"10.1210\/en.2010-0424","article-title":"Neutral antibodies to the TSH receptor are present in Graves\u2019 disease and regulate selective signaling cascades","volume":"151","author":"Morshed","year":"2010","journal-title":"Endocrinology"},{"key":"B8","first-page":"11","article-title":"Abnormal responses in the assay of thyrotrophin","volume":"34","author":"Adams","year":"1956","journal-title":"Proc Univ Otago Med Sch"},{"key":"B9","doi-asserted-by":"publisher","first-page":"193","DOI":"10.1590\/S0004-27302013000300005","article-title":"The clinical use of thyroid function tests","volume":"57","author":"de Carvalho","year":"2013","journal-title":"Arq Bras Endocrinol Metabol"},{"key":"B10","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1507\/endocrj.50.113","article-title":"TSH-receptor antibody measurement in patients with various thyrotoxicosis and Hashimoto\u2019s thyroiditis: a comparison of two two-step assays, coated plate ELISA using porcine TSH-receptor and coated tube radioassay using human recombinant TSH-receptor","volume":"50","author":"Kamijo","year":"2003","journal-title":"Endocr J"},{"key":"B11","doi-asserted-by":"publisher","first-page":"103","DOI":"10.3109\/08916938909019959","article-title":"Assays of TSH-receptor antibodies in 576 patients with various thyroid disorders: their incidence, significance and clinical usefulness","volume":"3","author":"Macchia","year":"1989","journal-title":"Autoimmunity"},{"key":"B12","doi-asserted-by":"publisher","first-page":"723","DOI":"10.1172\/jci114768","article-title":"Thyroid-stimulating antibody activity between different immunoglobulin G subclasses","volume":"86","author":"Weetman","year":"1990","journal-title":"J Clin Invest"},{"key":"B13","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1111\/j.1365-2265.1992.tb02297.x","article-title":"The IgG subclass distribution of TSH receptor blocking antibodies in primary hypothyroidism","volume":"37","author":"Kraiem","year":"1992","journal-title":"Clin Endocrinol"},{"key":"B14","doi-asserted-by":"publisher","first-page":"703","DOI":"10.1507\/endocrj.48.703","article-title":"Blocking type anti-TSH receptor antibodies detected by radioreceptor assay in Graves\u2019 disease","volume":"48","author":"Tada","year":"2001","journal-title":"Endocr J"},{"key":"B15","doi-asserted-by":"publisher","first-page":"579","DOI":"10.1089\/thy.2000.10.579","article-title":"The prevalence and clinical significance of blocking thyrotropin receptor antibodies in untreated hyperthyroid Graves\u2019 disease","volume":"10","author":"Kim","year":"2000","journal-title":"Thyroid"},{"key":"B16","doi-asserted-by":"publisher","first-page":"3781","DOI":"10.1210\/jcem.83.11.5056-2","article-title":"TSH receptor antibody measurement in the diagnosis and management of Graves\u2019 disease is rarely necessary","volume":"83","author":"Roti","year":"1988","journal-title":"J Clin Endocrinol Metab"},{"key":"B17","doi-asserted-by":"publisher","first-page":"28","DOI":"10.3389\/fendo.2017.00028","article-title":"TSH receptor antibody functionality and nomenclature","volume":"8","author":"Kahaly","year":"2017","journal-title":"Front Endocrinol"},{"key":"B18","doi-asserted-by":"publisher","first-page":"165487","DOI":"10.1155\/2014\/165487","article-title":"Association between TSH-receptor autoimmunity, hyperthyroidism, goitre, and orbitopathy in 208 Patients included in the remission induction and sustenance in Graves\u2019 disease study","volume":"2014","author":"Laurberg","year":"2014","journal-title":"J Thyroid Res"},{"key":"B19","doi-asserted-by":"publisher","first-page":"26","DOI":"10.7326\/0003-4819-103-1-26","article-title":"Primary myxedema with thyrotrophin-binding inhibitor immunoglobulins. Clinical and laboratory findings in 15 patients","volume":"103","author":"Konishi","year":"1985","journal-title":"Ann Intern Med"},{"key":"B20","doi-asserted-by":"publisher","first-page":"1004","DOI":"10.1089\/thy.2016.0017","article-title":"Thyrotropin receptor antibody levels at diagnosis and after thionamide course predict Graves\u2019 disease relapse","volume":"26","author":"Tun","year":"2016","journal-title":"Thyroid"},{"key":"B21","doi-asserted-by":"publisher","first-page":"182472","DOI":"10.1155\/2013\/182472","article-title":"Thyroid autoantibodies in pregnancy: their role, regulation and clinical relevance","volume":"2013","author":"Balucan","year":"2013","journal-title":"J Thyroid Res"},{"key":"B22","doi-asserted-by":"publisher","first-page":"192","DOI":"10.1210\/edrv-13-2-192","article-title":"The molecular biology of thyroid peroxidase: cloning, expression and role as autoantigen in autoimmune thyroid disease","volume":"13","author":"McLachlan","year":"1992","journal-title":"Endocr Rev"},{"key":"B23","doi-asserted-by":"publisher","first-page":"4568","DOI":"10.1074\/jbc.M408042200","article-title":"Endoproteolytic cleavage of human thyroperoxidase: role of the propeptide in the protein folding process","volume":"280","author":"Le Fourn","year":"2005","journal-title":"J Biol Chem"},{"key":"B24","doi-asserted-by":"publisher","first-page":"459","DOI":"10.1111\/j.1365-2249.1991.tb05749.x","article-title":"Anti-thyroid peroxidase antibodies in sera from healthy subjects and from patients with chronic thyroiditis: differences in the ability to inhibit thyroid peroxidase activities","volume":"85","author":"Kohno","year":"1991","journal-title":"Clin Exp Immunol"},{"key":"B25","doi-asserted-by":"crossref","first-page":"1392","DOI":"10.1093\/clinchem\/43.8.1392","article-title":"Effect of anti-thyroid peroxidase (TPO) antibodies on TPO activity measured by chemiluminescence assay","volume":"43","author":"Kaczur","year":"1997","journal-title":"Clin Chem"},{"key":"B26","doi-asserted-by":"publisher","first-page":"172","DOI":"10.1111\/j.1365-2249.2008.03756.x","article-title":"Distribution of immunoglobulin G subclasses of anti-thyroid peroxidase antibody in sera from patients with Hashimoto\u2019s thyroiditis with different thyroid functional status","volume":"154","author":"Xie","year":"2008","journal-title":"Clin Exp Immunol"},{"key":"B27","doi-asserted-by":"publisher","first-page":"504","DOI":"10.1089\/thy.2015.0592","article-title":"Oxidative stress and advanced glycation end products in Hashimoto\u2019s thyroiditis","volume":"26","author":"Ruggeri","year":"2016","journal-title":"Thyroid"},{"key":"B28","doi-asserted-by":"publisher","first-page":"576","DOI":"10.2174\/138920211798120763","article-title":"Hashimoto\u2019s thyroiditis: from genes to the disease","volume":"12","author":"Zaletel","year":"2011","journal-title":"Curr Genomics"},{"key":"B29","article-title":"Graves\u2019 disease and the manifestations of thyrotoxicosis","volume-title":"Endotext","author":"DeGroot","year":"2000"},{"key":"B30","doi-asserted-by":"publisher","first-page":"591","DOI":"10.1210\/jc.2007-1199","article-title":"Characterization of thyroglobulin epitopes in patients with autoimmune and non-autoimmune thyroid diseases using recombinant human monoclonal thyroglobulin autoantibodies","volume":"93","author":"Latrofa","year":"2008","journal-title":"J Clin Endocrinol Metab"},{"key":"B31","first-page":"73","article-title":"Immunology of human thyroid disease","volume-title":"Autoimmune Diseases of the Endocrine System","author":"Volpe","year":"1990"},{"key":"B32","doi-asserted-by":"publisher","first-page":"977","DOI":"10.1210\/jcem.80.3.7533775","article-title":"Monoclonal thyroglobulin autoantibodies: variable region analysis and epitope recognition","volume":"80","author":"Prentice","year":"1995","journal-title":"J Clin Endocrinol Metab"},{"key":"B33","first-page":"1583","article-title":"Chapter 83: Chronic (Hashimoto\u2019s) thyroiditis","volume-title":"Endocrinology Adult and Pediatric: The Thyroid Gland E-Book","author":"Lazarus","year":"2010"},{"key":"B34","article-title":"Chapter 13: Autoimmunity and transplantation","volume-title":"The Immune System in Health and Disease","author":"Janeway","year":"2001"},{"key":"B35","doi-asserted-by":"publisher","first-page":"648","DOI":"10.7439\/ijbar","article-title":"Prevalence of hypothyroidism and its association with anti-thyroid peroxidase antibody among adult sea food consuming population attending a tertiary health care centre in Kerala","volume":"6","author":"Cyriac","year":"2015","journal-title":"Int J Biomed Adv Res"},{"key":"B36","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1530\/eje-08-0192","article-title":"Thyroid and the environment: exposure to excessive nutritional iodine increases the prevalence of thyroid disorders in Sao Paulo, Brazil","volume":"159","author":"Camargo","year":"2008","journal-title":"Eur J Endocrinol"},{"key":"B37","doi-asserted-by":"publisher","first-page":"464","DOI":"10.1111\/j.1365-2249.1994.tb05514.x","article-title":"IgG subclass distribution of thyroglobulin antibodies in patients with thyroid disease","volume":"98","author":"Caturegli","year":"1994","journal-title":"Clin Exp Immunol"},{"key":"B38","doi-asserted-by":"publisher","first-page":"3937","DOI":"10.1210\/jcem.85.10.6884","article-title":"Rarity of anti-Na+\/I- symporter (NIS) antibody with iodide uptake inhibiting activity in autoimmune thyroid diseases (AITD)","volume":"85","author":"Chin","year":"2000","journal-title":"J Clin Endocrinol Metab"},{"key":"B39","doi-asserted-by":"publisher","first-page":"138","DOI":"10.1089\/thy.2016.0442","article-title":"Anti-thyrotropin autoantibodies in patients with macro-thyrotropin and long-term changes in macro-thyrotropin and serum thyrotropin levels","volume":"27","author":"Hattori","year":"2017","journal-title":"Thyroid"},{"key":"B40","first-page":"575","article-title":"Diagnosis and management of Graves\u2019 disease","volume":"168","author":"Ginsberg","year":"2003","journal-title":"CMAJ"},{"key":"B41","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1530\/eje-07-0450","article-title":"TSH-receptor autoimmunity in Graves\u2019 disease after therapy with anti-thyroid drugs, surgery, or radioiodine: a 5-year prospective randomized study","volume":"158","author":"Laurberg","year":"2008","journal-title":"Eur J Endocrinol"},{"key":"B42","doi-asserted-by":"publisher","first-page":"1103","DOI":"10.1089\/thy.2007.0072","article-title":"Persistence of thyrotropin (TSH) receptor antibodies in children and adolescents with Graves\u2019 disease treated using antithyroid medication","volume":"17","author":"Smith","year":"2007","journal-title":"Thyroid"},{"key":"B43","doi-asserted-by":"publisher","first-page":"661","DOI":"10.1210\/jcem-71-3-661","article-title":"Antithyroid peroxidase autoantibodies in thyroid diseases","volume":"71","author":"Mariotti","year":"1990","journal-title":"J Clin Endocrinol Metab"},{"key":"B44","doi-asserted-by":"publisher","first-page":"755","DOI":"10.1089\/thy.2008.0008","article-title":"Long-term follow-up of antithyroid peroxidase antibodies in patients with chronic autoimmune thyroiditis (Hashimoto\u2019s thyroiditis) treated with levothyroxine","volume":"18","author":"Schmidt","year":"2008","journal-title":"Thyroid"},{"key":"B45","volume-title":"Antithyroid Antibody","author":"Elhomsy","year":"2014"},{"key":"B46","doi-asserted-by":"publisher","first-page":"800","DOI":"10.1097\/mib.0000000000000018","article-title":"Opposing effects of smoking in ulcerative colitis and Crohn\u2019s disease may be explained by differential effects on dendritic cells","volume":"20","author":"Ueno","year":"2014","journal-title":"Inflamm Bowel Dis"},{"key":"B47","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1007\/BF02893034","article-title":"Autoimmune thyroid disorders-an update","volume":"20","author":"Swain","year":"2005","journal-title":"Indian J Clin Biochem"},{"key":"B48","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1111\/cen.12106","article-title":"Graves\u2019 hyperthyroidism and moderate alcohol consumption: evidence for disease prevention","volume":"79","author":"Carle","year":"2013","journal-title":"Clin Endocrinol"},{"key":"B49","doi-asserted-by":"publisher","first-page":"483","DOI":"10.1530\/eje-12-0356","article-title":"Moderate alcohol consumption may protect against overt autoimmune hypothyroidism: a population-based case-control study","volume":"167","author":"Carle","year":"2012","journal-title":"Eur J Endocrinol"},{"key":"B50","doi-asserted-by":"publisher","first-page":"S111","DOI":"10.1017\/s0007114507838049","article-title":"Moderate alcohol consumption and the immune system: a review","volume":"98","author":"Romeo","year":"2007","journal-title":"Br J Nutr"},{"key":"B51","doi-asserted-by":"publisher","first-page":"1681","DOI":"10.1089\/thy.2016.0256","article-title":"Selenium supplementation significantly reduces thyroid autoantibody levels in patients with chronic autoimmune thyroiditis: a systematic review and meta-analysis","volume":"26","author":"Wichman","year":"2016","journal-title":"Thyroid"},{"key":"B52","unstructured":"Autoimmunity to the thyroid gland WeetmanA DeGrootLJ Thyroid Disease Manager2016"},{"key":"B53","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1177\/2042018810382481","article-title":"Endocrine and metabolic emergencies: thyroid storm","volume":"1","author":"Carroll","year":"2010","journal-title":"Ther Adv Endocrinol Metab"},{"key":"B54","unstructured":"KaczorT Iodine and Cancer: A Summary of the Evidence to Date2014"},{"key":"B55","doi-asserted-by":"publisher","first-page":"548","DOI":"10.4236\/ns.2015.712055","article-title":"Iodine \u2013 a potential antioxidant and the role of iodine\/iodide in health and disease","volume":"7","author":"Winkler","year":"2015","journal-title":"Nat Sci"},{"key":"B56","doi-asserted-by":"publisher","first-page":"302537","DOI":"10.1155\/2012\/302537","article-title":"The role of oxidative stress on the pathogenesis of Graves\u2019 disease","volume":"2012","author":"Zarkovic","year":"2012","journal-title":"J Thyroid Res"},{"key":"B57","doi-asserted-by":"publisher","first-page":"R241","DOI":"10.1530\/EJE-14-0047","article-title":"Mechanisms in endocrinology: autoimmune thyroid disease: old and new players","volume":"170","author":"Effraimidis","year":"2014","journal-title":"Eur J Endocrinol"},{"key":"B58","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1186\/1743-422x-6-5","article-title":"Viruses and thyroiditis: an update","volume":"6","author":"Desailloud","year":"2009","journal-title":"Virol J"},{"key":"B59","doi-asserted-by":"publisher","first-page":"863","DOI":"10.1089\/thy.2012.0507","article-title":"Hepatitis C virus infection of a thyroid cell line: implications for pathogenesis of hepatitis C virus and thyroiditis","volume":"23","author":"Blackard","year":"2013","journal-title":"Thyroid"},{"key":"B60","doi-asserted-by":"publisher","first-page":"315","DOI":"10.1089\/thy.1991.1.315","article-title":"Immunoglobulins of patients recovering from Yersinia enterocolitica infections exhibit Graves\u2019 disease-like activity in human thyroid membranes","volume":"1","author":"Wolf","year":"1991","journal-title":"Thyroid"},{"key":"B61","first-page":"321","article-title":"Does the gut microbiota trigger Hashimoto\u2019s thyroiditis?","volume":"14","author":"Mori","year":"2012","journal-title":"Discov Med"},{"key":"B62","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1097\/00004836-199806000-00008","article-title":"Helicobacter pylori infection is markedly increased in patients with autoimmune atrophic thyroiditis","volume":"26","author":"de Luis","year":"1998","journal-title":"J Clin Gastroenterol"},{"key":"B63","doi-asserted-by":"publisher","first-page":"4693","DOI":"10.4049\/jimmunol.1002631","article-title":"IFN-alpha mediates the development of autoimmunity both by direct tissue toxicity and through immune cell recruitment mechanisms","volume":"186","author":"Akeno","year":"2011","journal-title":"J Immunol"},{"key":"B64","doi-asserted-by":"publisher","first-page":"674","DOI":"10.1210\/jc.2008-0095","article-title":"Infection and autoimmune thyroid disease","volume":"93","author":"Davies","year":"2008","journal-title":"J Clin Endocrinol Metab"},{"key":"B65","doi-asserted-by":"publisher","first-page":"541","DOI":"10.1016\/0140-6736(91)91103-2","article-title":"Reversible thyroid dysfunction during treatment with GM-CSF","volume":"338","author":"Hoekman","year":"1991","journal-title":"Lancet"},{"key":"B66","doi-asserted-by":"publisher","first-page":"4431","DOI":"10.1210\/jc.2016-2300","article-title":"Incidence of thyroid-related adverse events in melanoma patients treated with pembrolizumab","volume":"101","author":"de Filette","year":"2016","journal-title":"J Clin Endocrinol Metab"},{"key":"B67","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1056\/nejm198001033020105","article-title":"Hypothyroidism in workers exposed to polybrominated biphenyls","volume":"302","author":"Bahn","year":"1980","journal-title":"N Engl J Med"},{"key":"B68","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1186\/1756-6614-6-3","article-title":"Spectrum of lithium induced thyroid abnormalities: a current perspective","volume":"6","author":"Kibirige","year":"2013","journal-title":"Thyroid Res"},{"key":"B69","doi-asserted-by":"publisher","first-page":"599","DOI":"10.1056\/NEJM199108293250902","article-title":"Thyroid diseases after treatment of Hodgkin\u2019s disease","volume":"325","author":"Hancock","year":"1991","journal-title":"N Engl J Med"},{"key":"B70","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1530\/eje.1.02060","article-title":"The relative importance of genetic and environmental effects for the early stages of thyroid autoimmunity: a study of healthy Danish twins","volume":"154","author":"Hansen","year":"2006","journal-title":"Eur J Endocrinol"},{"key":"B71","doi-asserted-by":"publisher","first-page":"439","DOI":"10.1507\/endocrj.EJ11-0381","article-title":"Association of protein tyrosine phosphatase nonreceptor 22 (PTPN22) C1858T gene polymorphism with susceptibility to autoimmune thyroid diseases: a meta-analysis","volume":"59","author":"Luo","year":"2012","journal-title":"Endocr J"},{"key":"B72","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1146\/annurev-pathol-012513-104713","article-title":"Mechanisms of autoimmune thyroid diseases: from genetics to epigenetics","volume":"9","author":"Tomer","year":"2014","journal-title":"Annu Rev Pathol"},{"key":"B73","doi-asserted-by":"publisher","first-page":"600","DOI":"10.2353\/ajpath.2008.071008","article-title":"Sex differences in autoimmune disease from a pathological perspective","volume":"173","author":"Fairweather","year":"2008","journal-title":"Am J Pathol"},{"key":"B74","doi-asserted-by":"publisher","first-page":"366","DOI":"10.1016\/j.autrev.2006.10.001","article-title":"Gender and autoimmunity","volume":"6","author":"Zandman-Goddard","year":"2007","journal-title":"Autoimmun Rev"},{"key":"B75","doi-asserted-by":"publisher","first-page":"347","DOI":"10.1016\/j.yfrne.2014.04.004","article-title":"Gender differences in autoimmune disease","volume":"35","author":"Ngo","year":"2014","journal-title":"Front Neuroendocrinol"},{"key":"B76","doi-asserted-by":"publisher","first-page":"J193","DOI":"10.1016\/j.jaut.2011.11.011","article-title":"Increased loss of the Y chromosome in peripheral blood cells in male patients with autoimmune thyroiditis","volume":"38","author":"Persani","year":"2012","journal-title":"J Autoimmun"},{"key":"B77","doi-asserted-by":"publisher","first-page":"S17","DOI":"10.1089\/105072504323024552","article-title":"The interrelationships between thyroid dysfunction and hypogonadism in men and boys","volume":"14","author":"Meikle","year":"2004","journal-title":"Thyroid"},{"key":"B78","doi-asserted-by":"publisher","first-page":"363","DOI":"10.1530\/eje.0.1500363","article-title":"High prevalence of autoimmune thyroiditis in patients with polycystic ovary syndrome","volume":"150","author":"Janssen","year":"2004","journal-title":"Eur J Endocrinol"},{"key":"B79","doi-asserted-by":"publisher","first-page":"531969","DOI":"10.1155\/2014\/531969","article-title":"Symptoms and signs associated with postpartum thyroiditis","volume":"2014","author":"Groer","year":"2014","journal-title":"J Thyroid Res"},{"key":"B80","doi-asserted-by":"publisher","first-page":"2494","DOI":"10.1210\/jcem.86.6.7540","article-title":"Evidence of fetal microchimerism in Hashimoto\u2019s thyroiditis","volume":"86","author":"Klintschar","year":"2001","journal-title":"J Clin Endocrinol Metab"},{"key":"B81","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1007\/BF03401283","article-title":"An overview of the pathogenesis of thyroid autoimmunity","volume":"12","author":"Cogni","year":"2013","journal-title":"Hormones"},{"key":"B82","doi-asserted-by":"publisher","first-page":"150","DOI":"10.5603\/ep.2014.0021","article-title":"The role of the immune system and cytokines involved in the pathogenesis of autoimmune thyroid disease (AITD)","volume":"65","author":"Mikos","year":"2014","journal-title":"Endokrynol Pol"},{"key":"B83","doi-asserted-by":"publisher","first-page":"702","DOI":"10.1055\/s-0035-1548832","article-title":"The pathogenesis of Hashimoto\u2019s thyroiditis: further developments in our understanding","volume":"47","author":"Ajjan","year":"2015","journal-title":"Horm Metab Res"},{"key":"B84","doi-asserted-by":"publisher","first-page":"979167","DOI":"10.1155\/2015\/979167","article-title":"Immune disorders in Hashimoto\u2019s thyroiditis: what do we know so far?","volume":"2015","author":"Pyzik","year":"2015","journal-title":"J Immunol Res"},{"key":"B85","doi-asserted-by":"publisher","first-page":"3661","DOI":"10.1210\/jc.2011-1568","article-title":"Innate immune activation and thyroid autoimmunity","volume":"96","author":"Kawashima","year":"2011","journal-title":"J Clin Endocrinol Metab"},{"key":"B86","doi-asserted-by":"publisher","first-page":"397","DOI":"10.1046\/j.1365-2265.2004.01978.x","article-title":"On the pathogenesis of autoimmune thyroid disease: a unifying hypothesis","volume":"60","author":"Fountoulakis","year":"2004","journal-title":"Clin Endocrinol"},{"key":"B87","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1186\/1824-7288-39-8","article-title":"Hashimoto\u2019s thyroiditis in childhood: presentation modes and evolution over time","volume":"39","author":"De Luca","year":"2013","journal-title":"Ital J Pediatr"},{"key":"B88","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1007\/BF03401282","article-title":"Hashimoto\u2019s thyroiditis: history and future outlook","volume":"12","author":"Hiromatsu","year":"2013","journal-title":"Hormones"},{"key":"B89","doi-asserted-by":"publisher","first-page":"231","DOI":"10.1159\/000452623","article-title":"Immunoglobulin G4-related thyroid diseases","volume":"5","author":"Kottahachchi","year":"2016","journal-title":"Eur Thyroid J"},{"key":"B90","doi-asserted-by":"publisher","first-page":"1309","DOI":"10.1210\/jc.2009-1794","article-title":"Distinct clinical, serological, and sonographic characteristics of Hashimoto\u2019s thyroiditis based with and without IgG4-positive plasma cells","volume":"95","author":"Li","year":"2010","journal-title":"J Clin Endocrinol Metab"},{"key":"B91","doi-asserted-by":"publisher","first-page":"160004","DOI":"10.1530\/edm-16-0004","article-title":"A novel immunopathological association of IgG4-RD and vasculitis with Hashimoto\u2019s thyroiditis","volume":"2016","author":"Minamino","year":"2016","journal-title":"Endocrinol Diabetes Metab Case Rep"},{"key":"B92","doi-asserted-by":"publisher","first-page":"317","DOI":"10.1089\/105072503321669776","article-title":"Ord-Hashimoto\u2019s disease: renaming a common disorder \u2013 again","volume":"13","author":"Davies","year":"2003","journal-title":"Thyroid"},{"key":"B93","doi-asserted-by":"publisher","first-page":"833","DOI":"10.1210\/jc.2008-1370","article-title":"Thyroid volume in hypothyroidism due to autoimmune disease follows a unimodal distribution: evidence against primary thyroid atrophy and autoimmune thyroiditis being distinct diseases","volume":"94","author":"Carle","year":"2009","journal-title":"J Clin Endocrinol Metab"},{"key":"B94","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1007\/978-1-60327-285-8_42","article-title":"V. Endocrine and reproductive autoimmune diseases. Atrophic thyroiditis","volume-title":"Diagnostic Criteria in Autoimmune Diseases","author":"Jara","year":"2008"},{"key":"B95","doi-asserted-by":"publisher","first-page":"675703","DOI":"10.4061\/2011\/675703","article-title":"Autoimmune thyroid diseases in children","volume":"2011","author":"Cappa","year":"2010","journal-title":"J Thyroid Res"},{"key":"B96","doi-asserted-by":"publisher","first-page":"988","DOI":"10.4158\/ep12280.gl","article-title":"Clinical practice guidelines for hypothyroidism in adults: cosponsored by the American Association of Clinical Endocrinologists and the American Thyroid Association","volume":"18","author":"Garber","year":"2012","journal-title":"Endocr Pract"},{"key":"B97","doi-asserted-by":"publisher","first-page":"1236","DOI":"10.1056\/NEJM200010263431707","article-title":"Graves\u2019 disease","volume":"343","author":"Weetman","year":"2000","journal-title":"N Engl J Med"},{"key":"B98","doi-asserted-by":"publisher","first-page":"1051","DOI":"10.1210\/jcem-73-5-1051","article-title":"Inverse relation between iodine intake and thyroid blood flow: color Doppler flow imaging in euthyroid humans","volume":"73","author":"Arntzenius","year":"1991","journal-title":"J Clin Endocrinol Metab"},{"key":"B99","doi-asserted-by":"publisher","first-page":"864907","DOI":"10.1155\/2012\/864907","article-title":"Autoimmune thyroid disease in rheumatoid arthritis: a global perspective","volume":"2012","author":"Cardenas Roldan","year":"2012","journal-title":"Arthritis"},{"key":"B100","doi-asserted-by":"publisher","first-page":"168","DOI":"10.1080\/08916930802428114","article-title":"Rheumatoid arthritis and anti-thyroid antibodies","volume":"42","author":"Yavasoglu","year":"2009","journal-title":"Autoimmunity"},{"key":"B101","doi-asserted-by":"crossref","first-page":"39","DOI":"10.20452\/pamw.600","article-title":"Prevalence of thyroid diseases and antithyroid antibodies in women with rheumatoid arthritis","volume":"119","author":"Przygodzka","year":"2009","journal-title":"Pol Arch Med Wewn"},{"key":"B102","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1007\/978-0-387-09841-8_12","article-title":"Part V diabetes syndromes. Type 1 diabetes mellitus: epidemiology, genetics, pathogenesis, and clinical manifestations","volume-title":"Principles of Diabetes Mellitus","author":"Ali","year":"2010"},{"key":"B103","first-page":"31","article-title":"Thyroid function and anti-thyroid antibodies in Iranian patients with type 1 diabetes mellitus: influences of age and sex","volume":"7","author":"Sharifi","year":"2008","journal-title":"Iran J Allergy Asthma Immunol"},{"key":"B104","doi-asserted-by":"publisher","first-page":"849615","DOI":"10.1155\/2015\/849615","article-title":"Effect of advanced glycation end products on human thyroglobulin\u2019s antigenicity as identified by the use of sera from patients with Hashimoto\u2019s thyroiditis and gestational diabetes mellitus","volume":"2015","author":"Hatzioannou","year":"2015","journal-title":"Int J Endocrinol"},{"key":"B105","doi-asserted-by":"publisher","first-page":"184","DOI":"10.3121\/cmr.2007.738","article-title":"Celiac disease and autoimmune thyroid disease","volume":"5","author":"Ch\u2019ng","year":"2007","journal-title":"Clin Med Res"},{"key":"B106","doi-asserted-by":"publisher","first-page":"276575","DOI":"10.1155\/2015\/276575","article-title":"Antithyroid antibodies and thyroid function in pediatric patients with celiac disease","volume":"2015","author":"Kalyoncu","year":"2015","journal-title":"Int J Endocrinol"},{"key":"B107","first-page":"CLS1","article-title":"Study of thyroid auto-antibodies in patients with bronchial asthma and allergic rhinitis","volume":"5","author":"El-Aziz","year":"2010","journal-title":"Thyroid Sci"},{"key":"B108","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1016\/j.ejcdt.2015.08.018","article-title":"Association between anti-thyroid peroxidase antibody and asthma in women","volume":"11","author":"Fekri","year":"2012","journal-title":"Iran J Allergy Asthma Immunol"},{"key":"B109","first-page":"54","article-title":"Graves disease associated with chronic idiopathic urticaria: 2 case reports","volume":"19","author":"Bansal","year":"2009","journal-title":"J Investig Allergol Clin Immunol"},{"key":"B110","doi-asserted-by":"publisher","first-page":"861","DOI":"10.1007\/BF03346432","article-title":"Prevalence of interrelated autoantibodies in thyroid diseases and autoimmune disorders","volume":"31","author":"Nakamura","year":"2008","journal-title":"J Endocrinol Invest"},{"key":"B111","doi-asserted-by":"crossref","first-page":"394","DOI":"10.20452\/pamw.1829","article-title":"Relationship between rheumatoid arthritis activity and antithyroid antibodies","volume":"123","author":"Koszarny","year":"2013","journal-title":"Pol Arch Med Wewn"},{"key":"B112","doi-asserted-by":"publisher","first-page":"220","DOI":"10.1196\/annals.1375.034","article-title":"TSH receptor antibodies in subjects with type 1 diabetes mellitus","volume":"1079","author":"Unnikrishnan","year":"2006","journal-title":"Ann N Y Acad Sci"},{"key":"B113","doi-asserted-by":"publisher","first-page":"691","DOI":"10.1007\/s40618-014-0097-2","article-title":"Extrathyroidal manifestations of Graves\u2019 disease: a 2014 update","volume":"37","author":"Bartalena","year":"2014","journal-title":"J Endocrinol Invest"},{"key":"B114","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1097\/wno.0000000000000132","article-title":"The pathophysiology of thyroid eye disease","volume":"34","author":"Shan","year":"2014","journal-title":"J Neuroophthalmol"},{"key":"B115","doi-asserted-by":"publisher","first-page":"1194","DOI":"10.1210\/jcem.85.3.6433","article-title":"Cytokine profiles in eye muscle tissue and orbital fat tissue from patients with thyroid-associated ophthalmopathy","volume":"85","author":"Hiromatsu","year":"2000","journal-title":"J Clin Endocrinol Metab"},{"key":"B116","doi-asserted-by":"publisher","first-page":"2123","DOI":"10.1210\/jc.2009-2470","article-title":"A novel thyroid stimulating immunoglobulin bioassay is a functional indicator of activity and severity of Graves\u2019 orbitopathy","volume":"95","author":"Lytton","year":"2010","journal-title":"J Clin Endocrinol Metab"},{"key":"B117","doi-asserted-by":"publisher","first-page":"213","DOI":"10.3341\/kjo.2015.29.4.213","article-title":"Clinical association of thyroid stimulating hormone receptor antibody levels with disease severity in the chronic inactive stage of Graves\u2019 orbitopathy","volume":"29","author":"Woo","year":"2015","journal-title":"Korean J Ophthalmol"},{"key":"B118","doi-asserted-by":"publisher","first-page":"460","DOI":"10.4103\/2230-8210.95714","article-title":"Dermopathy of Graves\u2019 disease: clinico-pathological correlation","volume":"16","author":"Reddy","year":"2012","journal-title":"Indian J Endocrinol Metab"},{"key":"B119","doi-asserted-by":"publisher","first-page":"e981078","DOI":"10.4161\/19381980.2014.981078","article-title":"Thyroid dermopathy \u2013 a diagnostic clue of hidden hyperthyroidism","volume":"6","author":"Dhali","year":"2014","journal-title":"Dermatoendocrinol"},{"key":"B120","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1586\/eem.12.3","article-title":"Hashimoto\u2019s thyroiditis in patients with normal thyroid-stimulating hormone levels","volume":"7","author":"Promberger","year":"2012","journal-title":"Expert Rev Endocrinol Metab"},{"key":"B121","doi-asserted-by":"publisher","first-page":"585","DOI":"10.1007\/BF00900946","article-title":"Encephalopathy associated with Hashimoto thyroiditis: diagnosis and treatment","volume":"243","author":"Kothbauer-Margreiter","year":"1996","journal-title":"J Neurol"},{"key":"B122","volume-title":"CSF-Standards","year":"2014"},{"key":"B123","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1016\/j.bbi.2014.03.008","article-title":"Cognitive and affective dysfunctions in autoimmune thyroiditis","volume":"41","author":"Leyhe","year":"2014","journal-title":"Brain Behav Immun"},{"key":"B124","doi-asserted-by":"publisher","first-page":"600","DOI":"10.1111\/cen.12471","article-title":"Vestibular disorders in euthyroid patients with Hashimoto\u2019s thyroiditis: role of thyroid autoimmunity","volume":"81","author":"Chiarella","year":"2014","journal-title":"Clin Endocrinol"},{"key":"B125","doi-asserted-by":"publisher","first-page":"2358","DOI":"10.1210\/jc.2016-1049","article-title":"Subclinical hypothyroidism and thyroid autoimmunity are not associated with fecundity, pregnancy loss or live birth","volume":"101","author":"Plowden","year":"2016","journal-title":"J Clin Endocrinol Metab"},{"key":"B126","doi-asserted-by":"publisher","first-page":"775","DOI":"10.1093\/humupd\/dmw034","article-title":"The impact of thyroid autoimmunity on IVF\/ICSI outcome: a systematic review and meta-analysis","volume":"22","author":"Busnelli","year":"2016","journal-title":"Hum Reprod"},{"key":"B127","doi-asserted-by":"publisher","first-page":"e84647","DOI":"10.1371\/journal.pone.0084647","article-title":"Anti-TPO antibodies diffusion through the placental barrier during pregnancy","volume":"9","author":"Seror","year":"2014","journal-title":"PLoS One"},{"key":"B128","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1210\/jc.2016-2942","article-title":"Thyroid autoimmunity impairs the thyroidal response to hCG: two population-based prospective cohort studies","volume":"102","author":"Korevaar","year":"2016","journal-title":"J Clin Endocrinol Metab"},{"key":"B129","doi-asserted-by":"publisher","first-page":"1161","DOI":"10.1210\/jc.2009-1991","article-title":"Thyroid autoantibodies are associated with a reduced prevalence of frailty in community-dwelling older women","volume":"95","author":"Wang","year":"2010","journal-title":"J Clin Endocrinol Metab"},{"key":"B130","doi-asserted-by":"publisher","first-page":"474","DOI":"10.1210\/jc.2012-2978","article-title":"Clinical review: Hashimoto\u2019s thyroiditis and papillary thyroid carcinoma: is there a correlation?","volume":"98","author":"Jankovic","year":"2013","journal-title":"J Clin Endocrinol Metab"},{"key":"B131","doi-asserted-by":"publisher","first-page":"4499","DOI":"10.1158\/1078-0432.CCR-13-0095","article-title":"Phase I trial of a new schedule of romidepsin in patients with advanced cancers","volume":"19","author":"Amiri-Kordestani","year":"2013","journal-title":"Clin Cancer Res"},{"key":"B132","first-page":"1607","article-title":"High incidence of synchronous or metachronous breast cancer in patients with malignant and benign thyroid tumor or tumor-like disorders","volume":"29","author":"Nio","year":"2009","journal-title":"Anticancer Res"},{"key":"B133","doi-asserted-by":"publisher","first-page":"e0122958","DOI":"10.1371\/journal.pone.0122958","article-title":"Association of thyroid diseases with primary extra-thyroidal malignancies in women: results of a cross-sectional study of 6,386 patients","volume":"10","author":"Prinzi","year":"2015","journal-title":"PLoS One"},{"key":"B134","doi-asserted-by":"publisher","first-page":"879","DOI":"10.1089\/thy.2012.0568","article-title":"Cancer risk in patients with Graves\u2019 disease: a nationwide cohort study","volume":"23","author":"Chen","year":"2013","journal-title":"Thyroid"},{"key":"B135","doi-asserted-by":"publisher","first-page":"1397","DOI":"10.1038\/sj.bjc.6605624","article-title":"Cancer risk in patients hospitalised for Graves\u2019 disease: a population-based cohort study in Sweden","volume":"102","author":"Shu","year":"2010","journal-title":"Br J Cancer"},{"key":"B136","doi-asserted-by":"publisher","first-page":"349","DOI":"10.3275\/7141","article-title":"High prevalence of breast cancer in patients with benign thyroid diseases","volume":"34","author":"Muller","year":"2011","journal-title":"J Endocrinol Invest"},{"key":"B137","doi-asserted-by":"publisher","first-page":"553","DOI":"10.1016\/0277-5379(87)90319-1","article-title":"Thyroid function in patients with breast cancer","volume":"23","author":"Rasmusson","year":"1987","journal-title":"Eur J Cancer Clin Oncol"},{"key":"B138","doi-asserted-by":"publisher","first-page":"990","DOI":"10.1210\/jcem.81.3.8772562","article-title":"Relationship between breast cancer and thyroid disease: relevance of autoimmune thyroid disorders in breast malignancy","volume":"81","author":"Giani","year":"1996","journal-title":"J Clin Endocrinol Metab"},{"key":"B139","doi-asserted-by":"publisher","first-page":"R110","DOI":"10.1186\/bcr609","article-title":"Breast cancer in association with thyroid disorders","volume":"5","author":"Turken","year":"2003","journal-title":"Breast Cancer Res"},{"key":"B140","doi-asserted-by":"publisher","first-page":"35","DOI":"10.14310\/horm.2002.1152","article-title":"Lack of association between Hashimoto thyroiditis and breast cancer: a quantitative research synthesis","volume":"1","author":"Sarlis","year":"2002","journal-title":"Hormones"},{"key":"B141","doi-asserted-by":"publisher","first-page":"16","DOI":"10.4158\/ep14445.or","article-title":"Study of the prevalence of autoimmune thyroid disease in women with breast cancer","volume":"22","author":"Freitas","year":"2016","journal-title":"Endocr Pract"},{"key":"B142","first-page":"124","article-title":"Thyroid disorders in women with breast cancer","volume":"25","author":"Hajtmanova","year":"2012","journal-title":"Klin Onkol"},{"key":"B143","doi-asserted-by":"publisher","first-page":"114","DOI":"10.4158\/ep151035.co","article-title":"Commentary on \u2018study of the prevalence of autoimmune thyroid disease in women with breast cancer\u2019","volume":"22","author":"Sisti","year":"2016","journal-title":"Endocr Pract"},{"key":"B144","doi-asserted-by":"publisher","first-page":"1093","DOI":"10.1007\/s10552-015-0602-8","article-title":"Prospectively measured thyroid hormones and thyroid peroxidase antibodies in relation to risk of different breast cancer subgroups: a Malmo Diet and Cancer Study","volume":"26","author":"Brandt","year":"2015","journal-title":"Cancer Causes Control"},{"key":"B145","doi-asserted-by":"publisher","first-page":"2126","DOI":"10.1002\/ijc.27470","article-title":"Prospectively measured thyroid hormones and thyroid peroxidase antibodies in relation to breast cancer risk","volume":"131","author":"Tosovic","year":"2012","journal-title":"Int J Cancer"},{"key":"B146","doi-asserted-by":"publisher","first-page":"R33","DOI":"10.1186\/bcr2587","article-title":"Prospectively measured triiodothyronine levels are positively associated with breast cancer risk in postmenopausal women","volume":"12","author":"Tosovic","year":"2010","journal-title":"Breast Cancer Res"},{"key":"B147","doi-asserted-by":"publisher","first-page":"483","DOI":"10.1530\/eje-12-0564","article-title":"Triiodothyronine levels in relation to mortality from breast cancer and all causes: a population-based prospective cohort study","volume":"168","author":"Tosovic","year":"2013","journal-title":"Eur J Endocrinol"},{"key":"B148","doi-asserted-by":"publisher","first-page":"648670","DOI":"10.1155\/2015\/648670","article-title":"High thyroglobulin antibody levels increase the risk of differentiated thyroid carcinoma","volume":"2015","author":"Qin","year":"2015","journal-title":"Dis Markers"},{"key":"B149","doi-asserted-by":"publisher","first-page":"683","DOI":"10.1007\/s10549-014-2893-y","article-title":"Prevalence of breast cancer in thyroid diseases: results of a cross-sectional study of 3,921 patients","volume":"144","author":"Prinzi","year":"2014","journal-title":"Breast Cancer Res Treat"},{"key":"B150","doi-asserted-by":"publisher","first-page":"2711","DOI":"10.1210\/jcem.83.8.5049","article-title":"Serum thyroid peroxidase autoantibodies, thyroid volume, and outcome in breast carcinoma","volume":"83","author":"Smyth","year":"1998","journal-title":"J Clin Endocrinol Metab"},{"key":"B151","doi-asserted-by":"publisher","first-page":"260","DOI":"10.1210\/jcem-56-2-260","article-title":"The determination of thyroid volume by ultrasound and its relationship to body weight, age, and sex in normal subjects","volume":"56","author":"Hegedus","year":"1983","journal-title":"J Clin Endocrinol Metab"},{"key":"B152","first-page":"287","article-title":"Ultrasonographic measurement of the thyroid volume","volume":"28","author":"Ivanac","year":"2004","journal-title":"Coll Antropol"},{"key":"B153","doi-asserted-by":"crossref","first-page":"125","DOI":"10.29333\/ejgm\/82838","article-title":"Determination of thyroid volume and its relation with isthmus thickness","volume":"7","author":"\u015eeker","year":"2010","journal-title":"Eur J Gen Med"},{"key":"B154","doi-asserted-by":"publisher","first-page":"1169","DOI":"10.1007\/s10549-012-2019-3","article-title":"Benign thyroid disease is associated with breast cancer: a meta-analysis","volume":"133","author":"Hardefeldt","year":"2012","journal-title":"Breast Cancer Res Treat"},{"key":"B155","first-page":"1713","article-title":"Thyroid function in breast cancer patients","volume":"30","author":"Ditsch","year":"2010","journal-title":"Anticancer Res"},{"key":"B156","doi-asserted-by":"publisher","first-page":"1972","DOI":"10.1172\/JCI26031","article-title":"Thyrotropin receptor-associated diseases: from adenomata to Graves disease","volume":"115","author":"Davies","year":"2005","journal-title":"J Clin Invest"},{"key":"B157","doi-asserted-by":"publisher","first-page":"34","DOI":"10.12691\/ajms-2-2-2","article-title":"Effect of anti-thyroperoxidase on thyroid gland and breast tissue: a comprehensive review","volume":"2","author":"Kandi","year":"2014","journal-title":"Am J Med Stud"},{"key":"B158","doi-asserted-by":"publisher","first-page":"645","DOI":"10.1530\/eje.1.02108","article-title":"Thyroid autoimmunity in patients with malignant and benign breast diseases before surgery","volume":"154","author":"Giustarini","year":"2006","journal-title":"Eur J Endocrinol"},{"key":"B159","first-page":"425","article-title":"Breast cancer in association with thyroid disorders","volume":"14","author":"Michalaki","year":"2009","journal-title":"J BUON"},{"key":"B160","doi-asserted-by":"publisher","first-page":"6643","DOI":"10.7314\/APJCP.2014.15.16.6643","article-title":"Relationship between breast cancer and levels of serum thyroid hormones and antibodies: a meta-analysis","volume":"15","author":"Shi","year":"2014","journal-title":"Asian Pac J Cancer Prev"},{"key":"B161","first-page":"53","article-title":"Current management of inflammatory bowel disease and colorectal cancer","volume":"4","author":"Mattar","year":"2011","journal-title":"Gastrointest Cancer Res"},{"key":"B162","first-page":"96","article-title":"Thyroid peroxidase as an autoantigen in autoimmune thyroid disease: update 1994","volume-title":"Endocrine Review Monographs 3. Clinical and Molecular Aspects of Diseases of the Thyroid","author":"Rapoport","year":"1994"},{"key":"B163","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1046\/j.1365-3083.1997.d01-90.x","article-title":"Antibody reactivity against thyroid peroxidase and myeloperoxidase in autoimmune thyroiditis and systemic vasculitis","volume":"46","author":"Haapala","year":"1997","journal-title":"Scand J Immunol"},{"key":"B164","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1097\/00000441-200102000-00001","article-title":"Absence of cross-reactivity to myeloperoxidase of anti-thyroid microsomal antibodies in patients with autoimmune thyroid diseases","volume":"321","author":"Freire","year":"2001","journal-title":"Am J Med Sci"},{"key":"B165","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1007\/s10911-005-5401-5","article-title":"Is iodine a gatekeeper of the integrity of the mammary gland?","volume":"10","author":"Aceves","year":"2005","journal-title":"J Mammary Gland Biol Neoplasia"},{"key":"B166","doi-asserted-by":"publisher","first-page":"851","DOI":"10.1089\/thy.2007.0122","article-title":"Uptake and gene expression with antitumoral doses of iodine in thyroid and mammary gland: evidence that chronic administration has no harmful effects","volume":"17","author":"Anguiano","year":"2007","journal-title":"Thyroid"},{"key":"B167","doi-asserted-by":"publisher","first-page":"19762","DOI":"10.1074\/jbc.M600746200","article-title":"Molecular iodine induces caspase-independent apoptosis in human breast carcinoma cells involving the mitochondria-mediated pathway","volume":"281","author":"Shrivastava","year":"2006","journal-title":"J Biol Chem"},{"key":"B168","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1186\/1756-6614-6-8","article-title":"TSH receptor antibodies have predictive value for breast cancer \u2013 retrospective analysis","volume":"6","author":"Szychta","year":"2013","journal-title":"Thyroid Res"},{"key":"B169","doi-asserted-by":"publisher","first-page":"1253","DOI":"10.1089\/thy.2005.15.1253","article-title":"Hypothyroidism might be related to breast cancer in post-menopausal women","volume":"15","author":"Kuijpens","year":"2005","journal-title":"Thyroid"},{"key":"B170","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1136\/bmj","article-title":"Thyroid and other autoantibodies in British and Japanese women: an epidemiological study of breast cancer","volume":"1","author":"Mittra","year":"1976","journal-title":"Br Med J"},{"key":"B171","doi-asserted-by":"publisher","first-page":"734","DOI":"10.1007\/bf03350810","article-title":"Favorable predictive value of thyroid autoimmunity in high aggressive breast cancer","volume":"30","author":"Fiore","year":"2007","journal-title":"J Endocrinol Invest"},{"key":"B172","first-page":"1603","article-title":"Thyroid autoimmunity occurs more frequently in women with breast cancer compared to women with colorectal cancer and controls but it has no impact on relapse-free and overall survival","volume":"18","author":"Jiskra","year":"2007","journal-title":"Oncol Rep"},{"key":"B173","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1016\/j.jsbmb.2007.12.008","article-title":"Effects of thyroid hormones on human breast cancer cell proliferation","volume":"109","author":"Hall","year":"2008","journal-title":"J Steroid Biochem Mol Biol"},{"key":"B174","doi-asserted-by":"publisher","first-page":"629","DOI":"10.3892\/mco.2015.521","article-title":"Antithyroid peroxidase antibody positivity is associated with lower incidence of metastasis in breast cancer","volume":"3","author":"Kemal","year":"2015","journal-title":"Mol Clin Oncol"},{"key":"B175","doi-asserted-by":"publisher","first-page":"709","DOI":"10.1515\/cclm.2011.819","article-title":"Anti-thyroid peroxidase antibodies are associated with the absence of distant metastases in patients with newly diagnosed breast cancer","volume":"50","author":"Farahati","year":"2012","journal-title":"Clin Chem Lab Med"},{"key":"B176","doi-asserted-by":"publisher","first-page":"67","DOI":"10.5152\/tjbh.2015.2462","article-title":"Autoimmune thyroid disease and breast cancer prognosis","volume":"11","author":"\u00d6zmen","year":"2015","journal-title":"J Breast Health"},{"key":"B177","doi-asserted-by":"publisher","first-page":"595092","DOI":"10.4061\/2011\/595092","article-title":"Autophagy: friend or foe in breast cancer development, progression, and treatment","volume":"2011","author":"Berardi","year":"2011","journal-title":"Int J Breast Cancer"},{"key":"B178","article-title":"Chapter 12: Differentiation therapy in thyroid carcinoma","volume-title":"Updates in the Understanding and Management of Thyroid Cancer","author":"Fr\u00f6hlich","year":"2015"}],"container-title":["Frontiers in Immunology"],"original-title":[],"link":[{"URL":"http:\/\/journal.frontiersin.org\/article\/10.3389\/fimmu.2017.00521\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,18]],"date-time":"2025-06-18T05:46:51Z","timestamp":1750225611000},"score":1,"resource":{"primary":{"URL":"http:\/\/journal.frontiersin.org\/article\/10.3389\/fimmu.2017.00521\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,5,9]]},"references-count":178,"alternative-id":["10.3389\/fimmu.2017.00521"],"URL":"https:\/\/doi.org\/10.3389\/fimmu.2017.00521","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.727650851.793541917","asserted-by":"object"}]},"ISSN":["1664-3224"],"issn-type":[{"value":"1664-3224","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,5,9]]},"article-number":"521"}}