{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T05:41:10Z","timestamp":1770270070913,"version":"3.49.0"},"reference-count":20,"publisher":"Frontiers Media SA","content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Immunol."],"DOI":"10.3389\/fimmu.2018.00634","type":"journal-article","created":{"date-parts":[[2018,4,4]],"date-time":"2018-04-04T04:27:50Z","timestamp":1522816070000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":18,"title":["Semaphorin3A: A Potential Therapeutic Tool for Lupus Nephritis"],"prefix":"10.3389","volume":"9","author":[{"given":"Jacob","family":"Bejar","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ofra","family":"Kessler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adi D.","family":"Sabag","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edmond","family":"Sabo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ofer Ben","family":"Itzhak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gera","family":"Neufeld","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zahava","family":"Vadasz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2018,4,4]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"865","DOI":"10.1007\/s00296-017-3682-9","article-title":"Belimumab use, clinical outcomes and glucocorticoid reduction in patients with systemic lupus erythematosus receiving belimumab in clinical practice settings: results from the OBSErve Canada study","volume":"37","author":"Touma","year":"2017","journal-title":"Rheumatol Int"},{"key":"B2","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1007\/s12016-013-8360-4","article-title":"Semaphorins: their dual role in regulating immune-mediated diseases","volume":"47","author":"Vadasz","year":"2014","journal-title":"Clin Rev Allergy Immunol"},{"key":"B3","doi-asserted-by":"publisher","first-page":"1323","DOI":"10.1189\/jlb.2A1114-534R","article-title":"Class 3 semaphorins induce F-actin reorganization in human dendritic cells: role in cell migration","volume":"100","author":"Curreli","year":"2016","journal-title":"J Leukoc Biol"},{"key":"B4","doi-asserted-by":"publisher","first-page":"3321","DOI":"10.1182\/blood-2005-06-2445","article-title":"Semaphorin3A is expressed by tumor cells and alters T-cell signal transduction and function","volume":"107","author":"Catalano","year":"2006","journal-title":"Blood"},{"key":"B5","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1159\/000360477","article-title":"The role of B regulatory cells and semaphorin3A in atopic diseases","volume":"163","author":"Vadasz","year":"2014","journal-title":"Int Arch Allergy Immunol"},{"key":"B6","doi-asserted-by":"publisher","first-page":"1266","DOI":"10.1177\/0961203312456753","article-title":"Semaphorin3A \u2013 a marker for disease activity and a potential putative disease-modifying treatment in systemic lupus erythematosus","volume":"21","author":"Vadasz","year":"2012","journal-title":"Lupus"},{"key":"B7","doi-asserted-by":"publisher","first-page":"R146","DOI":"10.1186\/ar3881","article-title":"semaphorin3A is a marker for disease activity and a potential immunoregulator in systemic lupus erythematosus","volume":"14","author":"Vadasz","year":"2012","journal-title":"Arthritis Res Ther"},{"key":"B8","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1080\/08916930601118890","article-title":"Down-regulation of CD72 and increased surface IgG on B cells in patients with lupus nephritis","volume":"40","author":"Nakano","year":"2007","journal-title":"Autoimmunity"},{"key":"B9","doi-asserted-by":"publisher","first-page":"767","DOI":"10.1016\/j.semarthrit.2013.11.010","article-title":"A regulatory role for CD72 expression on B cells in systemic lupus erythematosus","volume":"43","author":"Vadasz","year":"2014","journal-title":"Semin Arthritis Rheum"},{"key":"B10","doi-asserted-by":"publisher","first-page":"1466","DOI":"10.1177\/0961203311417034","article-title":"The involvement of immune semaphorins and neuropilin-1 in lupus nephritis","volume":"20","author":"Vadasz","year":"2011","journal-title":"Lupus"},{"key":"B11","doi-asserted-by":"publisher","first-page":"26294","DOI":"10.1074\/jbc.M609711200","article-title":"Semaphorin-3A and semaphorin-3F work together to repel endothelial cells and to inhibit their survival by induction of apoptosis","volume":"282","author":"Guttmann-Raviv","year":"2007","journal-title":"J Biol Chem"},{"key":"B12","doi-asserted-by":"publisher","first-page":"675","DOI":"10.1038\/sj.gt.3302210","article-title":"Hydroporation as the mechanism of hydrodynamic delivery","volume":"11","author":"Zhang","year":"2004","journal-title":"Gene Ther"},{"key":"B13","first-page":"364","article-title":"Effects of sema3A derived from tumor cells on functions of dendritic cells","volume":"39","author":"Zhou","year":"2010","journal-title":"Zhejiang Da Xue Bao Yi Xue Ban"},{"key":"B14","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1016\/j.humimm.2009.01.026","article-title":"Expression and function of semaphoring 3A and its receptors in human monocyte-derived macrophages","volume":"70","author":"Ji","year":"2009","journal-title":"Hum Immunol"},{"key":"B15","doi-asserted-by":"publisher","first-page":"1782","DOI":"10.1002\/eji.200535601","article-title":"Immuno-suppressive role of semaphotin-3A on T cell proliferation is mediated by inhibition of actin cytoskeleton reorganization","volume":"36","author":"Lepelletier","year":"2006","journal-title":"Eur J Immunol"},{"key":"B16","doi-asserted-by":"publisher","first-page":"6373","DOI":"10.4049\/jimmunol.0903527","article-title":"The neuroimmune semaphorin3A reduces inflammation and progression of experimental autoimmune arthritis","volume":"185","author":"Catalano","year":"2010","journal-title":"J Immunol"},{"key":"B17","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1186\/1471-2474-14-40","article-title":"Decreased semaphorin3A expression correlates with disease activity and histological features of rheumatoid arthritis","volume":"14","author":"Takagawa","year":"2013","journal-title":"BMC Musculoskelet Disord"},{"key":"B18","doi-asserted-by":"publisher","first-page":"842","DOI":"10.1111\/j.1365-2133.2007.08410.x","article-title":"Decreased production of semaphorin3A in the lesional skin of atopic dermatitis","volume":"158","author":"Tominaga","year":"2008","journal-title":"Br J Dermatol"},{"key":"B19","doi-asserted-by":"publisher","first-page":"521","DOI":"10.2340\/00015555-1350","article-title":"Decreased expression of semaphorin3A, a neurite-collapsing factor, is associated with itch in psoriatic skin","volume":"92","author":"Kou","year":"2012","journal-title":"Acta Derm Venereol"},{"key":"B20","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1111\/1346-8138.12317","article-title":"Itch and nerve fibers with special reference to atopic dermatitis: therapeutic implications","volume":"41","author":"Tominaga","year":"2014","journal-title":"J Dermatol"}],"container-title":["Frontiers in Immunology"],"original-title":[],"link":[{"URL":"http:\/\/journal.frontiersin.org\/article\/10.3389\/fimmu.2018.00634\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,4,5]],"date-time":"2018-04-05T22:14:28Z","timestamp":1522966468000},"score":1,"resource":{"primary":{"URL":"http:\/\/journal.frontiersin.org\/article\/10.3389\/fimmu.2018.00634\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,4,4]]},"references-count":20,"alternative-id":["10.3389\/fimmu.2018.00634"],"URL":"https:\/\/doi.org\/10.3389\/fimmu.2018.00634","relation":{},"ISSN":["1664-3224"],"issn-type":[{"value":"1664-3224","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,4,4]]},"article-number":"634"}}